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  1. #31
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    Originally Posted by Dewey99 View Post
    The exact training protocol is in the process of being uploaded to the MuscleTech website. Each bottle of Clear Muscle will have a link to that protocol so people can see what the study participants did. I will post a link to the full protocol as soon as it is up.
    How about the nutrition logs each participant kept?

  2. #32
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    Originally Posted by SuperYou View Post
    How about the nutrition logs each participant kept?
    that is part of it as well
    "All that is necessary for the triumph of evil is that good men do nothing." (Edmund Burke)

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    Originally Posted by MVP42 View Post
    Will this be of any use for the average lifter or just people doing ridiculously taxing training like those in the study?
    It is more geared for taxing training and a bulking diet. A user still will benefit from a maintenance or cutting diet as well.

  4. #34
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    Originally Posted by emergency View Post
    the average lifter will see some results but nothing to the effect of doing hardcore training
    I'm assuming it will repair muscles faster/more effectively; therefore, you have to aggresively tear down your muscles to see the max effects (micro-tears due to training, etc)? Perhaps that same hardcore workout without MC wouldn't lead to the same progress because you would be overtraining your body?
    Last edited by jgd5796; 03-28-2014 at 01:11 PM.

  5. #35
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    Originally Posted by jgd5796 View Post
    I'm assuming it will repair muscles faster/more effectively; therefore, you have to aggresively tear down your muscles to see the max effects (micro-tears due to training, etc)? Perhaps that same hardcore workout without MC wouldn't lead to the same progress because you would be overtraining your body?
    This is partially correct. BetaTOR does greatly improve your recovery, but you don't necessarily have to be over-training to see results. Normal gym goers will see results from Clear Muscle as well, but those who train aggressively will get more out of it. The training regimen used in the study was very aggressive and that's how the subjects were able to make the gains they did in such a short time. The placebo group saw gains too, but way less than the BetaTOR group.
    RIP in Peace

  6. #36
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    its not a game changer guys its an INDUSTRY changer

    anyways, still very excited to see what it is.
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  7. #37
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    Originally Posted by Dewey99 View Post
    This is partially correct. BetaTOR does greatly improve your recovery, but you don't necessarily have to be over-training to see results. Normal gym goers will see results from Clear Muscle as well, but those who train aggressively will get more out of it. The training regimen used in the study was very aggressive and that's how the subjects were able to make the gains they did in such a short time. The placebo group saw gains too, but way less than the BetaTOR group.
    Yes there was a clear difference the two groups. Excited to pick this up.

  8. #38
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    I was just wondering, I read somewhere that 3 grams of the free acid form equates to 10 grams of the calcium bonded hmb ? would this lead to a similar response or there is a variable of bioavailability that could potentially lead to a difference ? Thanx in advance

  9. #39
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    Very excited for this one!

  10. #40
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    Originally Posted by rakan92 View Post
    I was just wondering, I read somewhere that 3 grams of the free acid form equates to 10 grams of the calcium bonded hmb ? would this lead to a similar response or there is a variable of bioavailability that could potentially lead to a difference ? Thanx in advance
    It is my understanding that mega-dosing HMB will never give you equal results to taking the HMB-FA. There are a couple reasons why this is true, but bioavailability is a large reason.
    RIP in Peace

  11. #41
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    Originally Posted by Dewey99 View Post
    It is my understanding that mega-dosing HMB will never give you equal results to taking the HMB-FA. There are a couple reasons why this is true, but bioavailability is a large reason.
    Leucine should do the same since its proven more effective?

  12. #42
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    Originally Posted by SuperYou View Post
    Leucine should do the same since its proven more effective?
    They don't work exactly the same way
    http://www.ncbi.nlm.nih.gov/pubmed/23551944
    Maintenance of skeletal muscle mass is contingent upon the dynamic equilibrium (fasted losses-fed gains) in protein turnover. Of all nutrients, the single amino acid leucine (Leu) possesses the most marked anabolic characteristics in acting as a trigger element for the initiation of protein synthesis. While the mechanisms by which Leu is 'sensed' have been the subject of great scrutiny, as a branched-chain amino acid, Leu can be catabolized within muscle, thus posing the possibility that metabolites of Leu could be involved in mediating the anabolic effect(s) of Leu. Our objective was to measure muscle protein anabolism in response to Leu and its metabolite HMB. Using [1,2-(13)C2]Leu and [(2)H5]phenylalanine tracers, and GC-MS/GC-C-IRMS we studied the effect of HMB or Leu alone on MPS (by tracer incorporation into myofibrils), and for HMB we also measured muscle proteolysis (by arteriovenous (A-V) dilution). Orally consumed 3.42 g free-acid (FA-HMB) HMB (providing 2.42 g of pure HMB) exhibited rapid bioavailability in plasma and muscle and, similarly to 3.42 g Leu, stimulated muscle protein synthesis (MPS; HMB +70% vs. Leu +110%). While HMB and Leu both increased anabolic signalling (mechanistic target of rapamycin; mTOR), this was more pronounced with Leu (i.e. p70S6K1 signalling 90 min vs. 30 min for HMB). HMB consumption also attenuated muscle protein breakdown (MPB; -57%) in an insulin-independent manner. We conclude that exogenous HMB induces acute muscle anabolism (increased MPS and reduced MPB) albeit perhaps via distinct, and/or additional mechanism(s) to Leu.

  13. #43
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    So for the samples, how many servings to gouge effects? do i have to be on the verge of rhabdo to benefit from it?

  14. #44
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    Originally Posted by Marshall28 View Post
    Yes there was a clear difference the two groups. Excited to pick this up.
    I see what you did there. :P
    Aspiring powerlifter.
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  15. #45
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    Originally Posted by DASBUNKER View Post
    So for the samples, how many servings to gouge effects? do i have to be on the verge of rhabdo to benefit from it?
    Since this is isn't a supplement that you will feel working, I would say 4 weeks would be a good amount of time to see results. Participants in the study (the HMB-FA group) gained an average of 6 lbs. of lean mass in the first four weeks. The training program ramped up as they went, so the first four weeks were not that crazy by normal training standards.

    We won't have samples of Clear Muscle, but will offer bottles for a logging promotion and to some of our field testers. The loggers are slated to get a 12 week supply of product.
    RIP in Peace

  16. #46
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    IMO this product will be most beneficial during periods of over reaching or perhaps also in caloric deficits

  17. #47
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    Originally Posted by itzDodge View Post
    They don't work exactly the same way
    ]
    Who said the same?

  18. #48
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    Originally Posted by itzDodge View Post
    They don't work exactly the same way
    http://www.ncbi.nlm.nih.gov/pubmed/23551944
    http://www.ncbi.nlm.nih.gov/pubmed/23551944

  19. #49
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    Originally Posted by itzDodge View Post
    IMO this product will be most beneficial during periods of over reaching or perhaps also in caloric deficits
    Use on a deficit is potentially appealing, but most people won't be happy spending that much money just to maintain muscle on a cut. I personally would, because you could cut your calories back pretty hard and still maintain lean mass as opposed to the normal cutting cycle where you either have to cut really slow or accept that you will lose hard-earned muscle along with fat if you cut quickly.
    RIP in Peace

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    Originally Posted by Dewey99 View Post
    Since this is isn't a supplement that you will feel working, I would say 4 weeks would be a good amount of time to see results. Participants in the study (the HMB-FA group) gained an average of 6 lbs. of lean mass in the first four weeks. The training program ramped up as they went, so the first four weeks were not that crazy by normal training standards.

    We won't have samples of Clear Muscle, but will offer bottles for a logging promotion and to some of our field testers. The loggers are slated to get a 12 week supply of product.
    Thanks for the answer.

    Originally Posted by SuperYou View Post
    http://www.ncbi.nlm.nih.gov/pubmed/24302558

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    Originally Posted by Dewey99 View Post
    Use on a deficit is potentially appealing, but most people won't be happy spending that much money just to maintain muscle on a cut. I personally would, because you could cut your calories back pretty hard and still maintain lean mass as opposed to the normal cutting cycle where you either have to cut really slow or accept that you will lose hard-earned muscle along with fat if you cut quickly.
    Could be particularly beneficial once you're in the single digits of BF% where losing fat without losing too much muscle becomes a lot more challenging.

  22. #52
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    Originally Posted by itzDodge View Post
    Could be particularly beneficial once you're in the single digits of BF% where losing fat without losing too much muscle becomes a lot more challenging.
    I would think this is where the appeal would lie for women also. Most women aren't looking to add substantial mass, but could benefit from using it on a cut.
    RIP in Peace

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    In the UK atm for my masters program. Will Clear Muscle be available on the Europe bb.com store at the same time as the US one?

  24. #54
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    Originally Posted by newtothelift View Post
    In the UK atm for my masters program. Will Clear Muscle be available on the Europe bb.com store at the same time as the US one?
    I would say yes but that is really a guess and not something we discussed the other day.
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  25. #55
    Registered User raydeezy's Avatar
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    pretty excited to see how effective this product will be when cutting

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    Originally Posted by Dewey99 View Post
    I would think this is where the appeal would lie for women also. Most women aren't looking to add substantial mass, but could benefit from using it on a cut.
    I completely agree Dewey. I myself am super excited to run clear muscle. So much excitement!
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    Originally Posted by itzDodge View Post
    They don't work exactly the same way
    http://www.ncbi.nlm.nih.gov/pubmed/23551944
    On the net, it appears to be as effective as leucine (anabolism + anti-catabolism), but leucine's effects persist longer

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    Originally Posted by raydeezy View Post
    pretty excited to see how effective this product will be when cutting
    I wonder if this could be the supplement that makes the bodybuilding myth of gaining muscle while losing fat a reality?

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    Originally Posted by itzDodge View Post
    IMO this product will be most beneficial during periods of over reaching or perhaps also in caloric deficits
    This product is best used during periods of overreaching and a bulking diet. It does have its benefits when in a caloric deficit though.

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    Originally Posted by Dewey99 View Post
    Use on a deficit is potentially appealing, but most people won't be happy spending that much money just to maintain muscle on a cut. I personally would, because you could cut your calories back pretty hard and still maintain lean mass as opposed to the normal cutting cycle where you either have to cut really slow or accept that you will lose hard-earned muscle along with fat if you cut quickly.
    Detouring a little from the main topic, if you are going to lose a lot of muscle on a cut, that's most probably a really ill-planned cut :P
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