Beta Alanine Possible Neurotoxin?

[DASBUNKER]

http://suppversity.blogspot.mx/2013/...otoxin-or.html

What do you think? could the cardio-neuro hazards realistically be an issue given normal dosing protocols? There's been some talk around here about the BA-Taurine relation but i haven't seen much conclusive data. Perhaps that's why some proteins now contain taurine, companies be looking out for us

[mtpaquette]

I ate Jack in the Box for breakfast. After taking a scoop of Fierce Dom pre I've felt disgusting and can't function enough to read that. This makes me sad.

[DASBUNKER]

Bold statement coming from a competing rep. ^^

[mtpaquette]

Bold statement coming from a competing rep. ^^

I've learned my lesson... don't eat Jack in the Box. The gf said the same thing.

[HY314]

cliffs?

[DASBUNKER]

cliffs?

BA may deplete taurine in the body and inhibit it's uptake, hinder antioxidant mechanism and lead to irregular kinase enzymes activities in the brain.

[poison]

I ate Jack in the Box for breakfast. After taking a scoop of Fierce Dom pre I've felt disgusting and can't function enough to read that. This makes me sad.

If you had asked us, we never would have recommended the JiB/FD stack.

[PinchTheBear]

"lmao" -my comprehensive analysis of this topic

[PerfectCreature]

By the looks of it, you would have a take a LOT of Beta Alanine, and have it digest immediately for it to become toxic.
It mentioned in the side notes that slow digesting of the BA, is not all the toxic.

The lab rats took .3 of their body weight, which if you calculate it out, is a sizable amount. Most pr-workouts have you taking below that amount even at the max dosages.

Not to mention the grammar and citation errors, and improper format of the referencing....

[DASBUNKER]

"lmao" -my comprehensive analysis of this topic

By the looks of it, you would have a take a LOT of Beta Alanine, and have it digest immediately for it to become toxic.
It mentioned in the side notes that slow digesting of the BA, is not all the toxic.

The lab rats took .3 of their body weight, which if you calculate it out, is a sizable amount. Most pr-workouts have you taking below that amount even at the max dosages.

Not to mention the grammar and citation errors, and improper format of the referencing....

so what you're saying is.. 3-5g/day no need to load?

[rbmorrison]

Not to mention the grammar and citation errors, and improper format of the referencing....

He is from Germany.

[Mr.Cooper69]

By the looks of it, you would have a take a LOT of Beta Alanine, and have it digest immediately for it to become toxic.
It mentioned in the side notes that slow digesting of the BA, is not all the toxic.

The lab rats took .3 of their body weight, which if you calculate it out, is a sizable amount. Most pr-workouts have you taking below that amount even at the max dosages.

Not to mention the grammar and citation errors, and improper format of the referencing....

You're quite incorrect in this analysis lol.



Buuuuut...the author of suppversity makes some quality articles. They tend to be a tad alarmist with respect to certain topics (beta-alanine, fish oil, TTA, etc). Bias is intrinsic to anyone's work and I don't blame him, but given how much else we know about b-alanine, take what he said with a grain of salt.

He is correct in saying that it's best to:

A. Take BA with meals
B. Split it up throughout the day

[DASBUNKER]

He is correct in saying that it's best to:

A. Take BA with meals
B. Split it up throughout the day

Interdasting i saw you comment something regarding the histidine in that aspect.. since several pres have it, i guess that will force most of us to take one of the doses on an empty stomach.

[Mr.Cooper69]

Interdasting i saw you comment something regarding the histidine in that aspect.. since several pres have it, i guess that will force most of us to take one of the doses on an empty stomach.

Yeah, definitely suboptimal, especially preworkout.

[powercage]

BA may deplete taurine in the body and inhibit it's uptake, hinder antioxidant mechanism and lead to irregular kinase enzymes activities in the brain.

Not relevant with the way people are dosing for bodybuilding

[DASBUNKER]

Yeah, definitely suboptimal, especially preworkout.

Mainly because of histidine or is there any other detrimental factor to it?

Not relevant with the way people are dosing for bodybuilding

[Mr.Cooper69]

Mainly because of histidine or is there any other detrimental factor to it?

Histamine release is detrimental and may even hinder breathing by decreasing available airway volume in the trachea.

[DASBUNKER]

Histamine release is detrimental and may even hinder breathing by decreasing available airway volume in the trachea.

I see.. i may have noticed something slightly like that when taking BA.. (no hypo)

Thanks will try it with food whenever possible.

[ISurfNudeBrah]

Yeah, definitely suboptimal, especially preworkout.

We talking histidine or histamine... Ive got bulk b-alanine caps with histidine is this bad

[Mr.Cooper69]

We talking histidine or histamine... Ive got bulk b-alanine caps with histidine is this bad

Histamine, which is a neurotransmitter centrally and implicated in allergic reactions peripherally

[eriquee]

They talking histamine, BA and histine should be fine, there is no reason to take histine though you get plenty from foods.

[ISurfNudeBrah]

Histamine, which is a neurotransmitter centrally and implicated in allergic reactions peripherally

Si senor I am aware of that, I was just confused by DASBUNKER's post below... thanks coop

Interdasting i saw you comment something regarding the histidine in that aspect.. since several pres have it, i guess that will force most of us to take one of the doses on an empty stomach.

They talking histamine, BA and histine should be fine, there is no reason to take histine though you get plenty from foods.

Right. Histidine.

edit: Coop any reason why my BA caps contain histidine though?.. It is Sci-fit brand so who knows..

[DASBUNKER]

It is Sci-fit brand so who knows..

lol

my bad on the confusion

[Mr.Cooper69]

Si senor I am aware of that, I was just confused by DASBUNKER's post below... thanks coop





Right. Histidine.

edit: Coop any reason why my BA caps contain histidine though?.. It is Sci-fit brand so who knows..

b-Alanine needs histidine to produce carnosine (end goal). In the human body, beta-alanine is the limiting substrate, so histidine won't really help or hurt you. Some data shows histidine may be beneficial at higher doses though