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  1. #1
    Registered User Pictoron's Avatar
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    Creatine Kre-Alkalyn: Pros and Cons?

    Basically just want to know the positives and negatives about Kre-Alkalyn compared to the other kinds of creatine? (Monohydrate mainly).
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  2. #2
    Team MuscleTech Rep mmafighterskiba's Avatar
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    Theres research on kre alkalyn, the biggest selling point is no bloat.

    Honestly the research on mono is more convincing in my opinion and its been around forever. Plus you cant beat the price of bulk monohydrate
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  3. #3
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  4. #4
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    Originally Posted by Pictoron View Post
    Basically just want to know the positives and negatives about Kre-Alkalyn compared to the other kinds of creatine? (Monohydrate mainly).
    I've used it and didnt mind. easy to take pills... but I think I still just prefer to go with micronized monohydrate powder. cheaper and just as effective, IMO
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  5. #5
    Echo In Eternity J-Rod's Avatar
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    Originally Posted by Pictoron View Post
    Basically just want to know the positives and negatives about Kre-Alkalyn compared to the other kinds of creatine? (Monohydrate mainly).
    Here is my copy and pasta of a summary on a study comparing Kre-Alkalyn to Creatine Monohydrate:

    J Int Soc Sports Nutr. 2012 Sep 13;9(1):43. doi: 10.1186/1550-2783-9-43.
    A buffered form of creatine does not promote greater changes in muscle creatine content, body composition, or training adaptations than creatine monohydrate.
    Jagim AR, Oliver JM, Sanchez A, Galvan E, Fluckey J, Riechman S, Greenwood M, Kelly K, Meininger C, Rasmussen C, Kreider RB.
    Source
    Department of Health and Kinesiology, Exercise and Sport Nutrition Laboratory, Texas A&M University, College Station, TX 77843-4243, USA. rkreider@hlkn.tamu.edu.
    Abstract

    BACKGROUND:

    Creatine monohydrate (CrM) has been consistently reported to increase muscle creatine content and improve high-intensity exercise capacity. However, a number of different forms of creatine have been purported to be more efficacious than CrM. The purpose of this study was to determine if a buffered creatine monohydrate (KA) that has been purported to promote greater creatine retention and training adaptations with fewer side effects at lower doses is more efficacious than CrM supplementation in resistance-trained individuals.

    METHODS:

    In a double-blind manner, 36 resistance-trained participants (20.2 ± 2 years, 181 ± 7 cm, 82.1 ± 12 kg, and 14.7 ± 5% body fat) were randomly assigned to supplement their diet with CrM (Creapure® AlzChem AG, Trostberg, Germany) at normal loading (4 x 5 g/d for 7-days) and maintenance (5 g/d for 21-days) doses; KA (Kre-Alkalyn®, All American Pharmaceutical, Billings, MT, USA) at manufacturer's recommended doses (KA-L, 1.5 g/d for 28-days); or, KA with equivalent loading (4 x 5 g/d for 7-days) and maintenance (5 g/d) doses of CrM (KA-H). Participants were asked to maintain their current training programs and record all workouts. Muscle biopsies from the vastus lateralis, fasting blood samples, body weight, DEXA determined body composition, and Wingate Anaerobic Capacity (WAC) tests were performed at 0, 7, and 28-days while 1RM strength tests were performed at 0 and 28-days. Data were analyzed by a repeated measures multivariate analysis of variance (MANOVA) and are presented as mean ± SD changes from baseline after 7 and 28-days, respectively.

    RESULTS:

    Muscle free creatine content obtained in a subgroup of 25 participants increased in all groups over time (1.4 ± 20.7 and 11.9 ± 24.0 mmol/kg DW, p = 0.03) after 7 and 28-days, respectively, with no significant differences among groups (KA-L -7.9 ± 22.3, 4.7 ± 27.0; KA-H 1.0 ± 12.8, 9.1 ± 23.2; CrM 11.3 ± 23.9, 22.3 ± 21.0 mmol/kg DW, p = 0.46). However, while no overall group differences were observed (p = 0.14), pairwise comparison between the KA-L and CrM groups revealed that changes in muscle creatine content tended to be greater in the CrM group (KA-L -1.1 ± 4.3, CrM 11.2 ± 4.3 mmol/kg DW, p = 0.053 [mean ± SEM]). Although some significant time effects were observed, no significant group x time interactions (p > 0.05) were observed in changes in body mass, fat free mass, fat mass, percent body fat, or total body water; bench press and leg press 1RM strength; WAC mean power, peak power, or total work; serum blood lipids, markers of catabolism and bone status, and serum electrolyte status; or, whole blood makers of lymphocytes and red cells. Serum creatinine levels increased in all groups (p < 0.001) with higher doses of creatine promoting greater increases in serum creatinine (p = 0.03) but the increases observed (0.1 - 0.2 mg/dl) were well within normal values for active individuals (i.e., <1.28 ± 0.2 mg/dl). Serum LDL was decreased to a greater degree following ingesting loading doses in the CrM group but returned to baseline during the maintenance phase. No side effects were reported.

    CONCLUSIONS:

    Neither manufacturers recommended doses of KA (1.5 g/d) or KA with equivalent loading (20 g/d for 7-days) and maintenance doses (5 g/d for 21-days) of CrM promoted greater changes in muscle creatine content, body composition, strength, or anaerobic capacity than CrM (20 g/d for 7-days, 5 g/d for 21-days). There was no evidence that supplementing the diet with a buffered form of creatine resulted in fewer side effects than CrM. These findings do not support claims that consuming a buffered form of creatine is a more efficacious and/or safer form of creatine to consume than creatine monohydrate.
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  6. #6
    Registered User snorkelman's Avatar
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    Kre-Alkalyn is inferior to monohydrate, especially when dosed at Kre-Alkalyn’s label recommendations.


    Here is a post from Lyle Mcdonald regarding his thoughts on Kre-Alkalyn:


    Here is a tweet from Layne Norton on Kre-Alkalyn:
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  7. #7
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    Pros: It's as good as creatine mono and Tums. Because that's what it is.

    Cons: Costs twice as much as a tub of creatine mono and a bottle of Tums.
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  8. #8
    Top Secret Nutrition Rep demonwareltd's Avatar
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    Originally Posted by BlueRev View Post
    I like it because i can get it as pills and makes it much easier to make sure i get my 3-5g per day.
    This is my rationale as well. As far as efficacy, I have used both and I saw little to no difference in strength or body weight (indicating) intra-muscular water remained unchanged. Check out the price for the large bottle of gelcaps in the bb.com store. Quite affordable IMO...

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  9. #9
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    1.) I like pill form 2.) AAEFX kre alk has caffeine
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  10. #10
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    Originally Posted by COZ999 View Post
    1.) I like pill form 2.) AAEFX kre alk has caffeine
    lol wut?
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  11. #11
    Echo In Eternity J-Rod's Avatar
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    Originally Posted by COZ999 View Post
    1.) I like pill form 2.) AAEFX kre alk has caffeine
    People do not read copy and past, but here is a copy and pasta of the conclusion of a good study:

    CONCLUSIONS:

    Neither manufacturers recommended doses of KA (1.5 g/d) or KA with equivalent loading (20 g/d for 7-days) and maintenance doses (5 g/d for 21-days) of CrM promoted greater changes in muscle creatine content, body composition, strength, or anaerobic capacity than CrM (20 g/d for 7-days, 5 g/d for 21-days). There was no evidence that supplementing the diet with a buffered form of creatine resulted in fewer side effects than CrM. These findings do not support claims that consuming a buffered form of creatine is a more efficacious and/or safer form of creatine to consume than creatine monohydrate.
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  12. #12
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    Originally Posted by COZ999 View Post
    1.) I like pill form 2.) AAEFX kre alk has caffeine
    The Flex Wheeler Signature version does, not the standard fare. Do you even product knowledge?
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  13. #13
    Registered User De__eB's Avatar
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    Pros: None

    Cons: 10x as expensive, significantly increased degradation to creatinine, significantly lower intramuscular PCR concentrations
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  14. #14
    ISOFLEX'D xStevenx's Avatar
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    Waste of freaking money.

    Get a tub of Allmax Creapure. $20 for a 200 Day supply and you are all set!

    http://www.bodybuilding.com/store/all/creatine.html

    Want the "benefits" of kre, then add in some baking soda. That is all that they do, but just charge a lot for it
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  15. #15
    Polski Bro mobikwa's Avatar
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    Originally Posted by De__eB View Post
    Pros: None

    Cons: 10x as expensive, significantly increased degradation to creatinine, significantly lower intramuscular PCR concentrations
    LOL wut?

    How does Kre Alk (Creatine mono + antacid) degrade into creatinine faster than creatine mono?
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  16. #16
    Registered User De__eB's Avatar
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    Originally Posted by mobikwa View Post
    LOL wut?

    How does Kre Alk (Creatine mono + antacid) degrade into creatinine faster than creatine mono?
    The study demonstrates it, the reason is:

    Creatine degradation is at its highest at ~3-4 pH.

    The empty pH of the stomach is 1-2 pH.

    Kre-alkalyne buffers its solution up to somewhere just above 7. But with a miniscule amount of said buffering ingredient.

    As a result this buffering is rapidly neutralized, bringing the pH of the stomach back down and through the peak degradation range of 3-4.

    As a result, the total degradation of kre-alkalyn ends up being higher than just taking plain creatine monohydrate.
    Last edited by De__eB; 04-02-2013 at 09:49 PM.
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    Originally Posted by Terrimonas View Post
    The Flex Wheeler Signature version does, not the standard fare. Do you even product knowledge?
    kre alk pro
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