***Official Nootropics Thread***

[xLGx]

What were you dosing it at, and alongside what else? What is the CILTEP stack, I am too lazy to google search. Prami is interesting stuff, had trouble dialing in the right dose

Recently, nothing. I'm currently cycling off a lot of supplements right now, stims and ALCAR included. I just had 750mg caps and would take it in the morning. I even tried 750mg in the morning and another 750mg later in the afternoon.

CILTEP is a theory that's relatively new in which the ultimate goal is to increase cAMP molecules in the brain with 3 simple ingredients. First is Forskolin, which we all know increases cAMP. Since PDE4 receptors block cAMP in our brains, a PDE4 inhibitor supplement is needed (Artichoke Extract). If we inhibit our PDE4 receptors and increase our cAMP, the idea is we will be more attentive, energetic and productive and our memory capabilities should increase. The last ingredient is the icing on the cake and is meant to be a dopamine increaser. There are a lot of ways you can go about increasing dopamine levels, but a lot of people have had success with L-phenylalanine. Standard dosing protocol is something like:

- 500mg Artichoke Extract
- Forskolin (I've seen ranges from 4mg-20mg)
- L-Phenylalanine (I've seen ranges from 500mg-1,000mg)

I've yet to try it but my ingredients are en route (extremely cheap as well). I'll report in here when I get a grasp of the effectiveness of this stack. For what it's worth, my good friend tried it yesterday and said it was the best nootropic stack he has ever tried [and he has tried it all].

[tmd17]

I'm going to start a CILTEP stack and possibly add Prami to it.

Wow, first time i've heard of this. Did a little reading on long term potentiation, makes a lot of sense to me. What's in the stack? Good call on the pram.

Edit: ^Wizard. Brb reading.

Double edit: Good stuff man, definitely interested. Keep us posted.

[Tomohawk92]

I take 10mg vinpocetine and 100mg phosphaditylserine in the same cup as 1g vitamin C, 4g potassium gluconate, creatine, BA and MSM. I then take my vitamin D, fish oil, zinc-copper and multi.

Is the vitC going to destroy everything before it gets used?

[itzDodge]

Recently, nothing. I'm currently cycling off a lot of supplements right now, stims and ALCAR included. I just had 750mg caps and would take it in the morning. I even tried 750mg in the morning and another 750mg later in the afternoon.

That's still a fairly conservative dose, I thoroughly enjoyed around 3g/daily. After a few months you go fill wizard mode

CILTEP is a theory that's relatively new in which the ultimate goal is to increase cAMP molecules in the brain with 3 simple ingredients. First is Forskolin, which we all know increases cAMP. Since PDE4 receptors block cAMP in our brains, a PDE4 inhibitor supplement is needed (Artichoke Extract). If we inhibit our PDE4 receptors and increase our cAMP, the idea is we will be more attentive, energetic and productive and our memory capabilities should increase. The last ingredient is the icing on the cake and is meant to be a dopamine increaser. There are a lot of ways you can go about increasing dopamine levels, but a lot of people have had success with L-phenylalanine. Standard dosing protocol is something like:

- 500mg Artichoke Extract
- Forskolin (I've seen ranges from 4mg-20mg)
- L-Phenylalanine (I've seen ranges from 500mg-1,000mg)

I've yet to try it but my ingredients are en route (extremely cheap as well). I'll report in here when I get a grasp of the effectiveness of this stack. For what it's worth, my good friend tried it yesterday and said it was the best nootropic stack he has ever tried [and he has tried it all].

I think this is making a lot of assumptions about neurochemistry but it's a nice idea. If anything I'd wager L-dopa a much better option for dopamine. Citicoline is also a nice option there and its multitude of effects on the brain are ballin but it is pricey sadly

I take 10mg vinpocetine and 100mg phosphaditylserine in the same cup as 1g vitamin C, 4g potassium gluconate, creatine, BA and MSM. I then take my vitamin D, fish oil, zinc-copper and multi.

Vinpocetine is a weak choice nootropic wise, did not get Andy's seal of approval=do not want lol

It is likely to cause more harm than good essentially as a potential to cause of headaches with little reward

[xLGx]

Double edit: Good stuff man, definitely interested. Keep us posted.

Will do.

Also, there is a study that Aniracetam effects are altered when LTP is induced:
http://www.ncbi.nlm.nih.gov/pubmed/9555053

This seems to be validated by users reporting negative interactions with stacking Aniracetam + CILTEP. This is one major reason why I've chosen the Pramiracetam route over the other racetams.

I think this is making a lot of assumptions about neurochemistry but it's a nice idea. If anything I'd wager L-dopa a much better option for dopamine. Citicoline is also a nice option there and its multitude of effects on the brain are ballin but it is pricey sadly

You're absolutely right. But it is a very interesting theory and worth a try at the very least.

Mucuna Pruriens have been used successfully in CILTEP. I'll probably dabble in both to see what is more effective.

[tmd17]

Here's a playlist of animation videos that explains long term potentiation, pretty interesting. Only like 3min long max.

Not sure how to embed a playlist:

http://www.youtube.com/watch?v=sTPa2...e=results_main

[DannySampsonite]

El Oh El.

Come on meow

[Synapsin]

Not that I am aware of. Steve was a pretty cool guy, and he sent me lots of stuff to play with. Those were the days

Oh you missed drama...And as for this thread...oh lawd.

[DannySampsonite]

This forum has a disturbing hard-on for aniracetam.

[cjwav34]

Currently dosing preworkout:
2g ALCAR
2g Choline Citrate
200mg caffeine
25mg ephedrine
200mcg Huperzine


Currently loving it, but I was curious if there was anything you all would recommend adding?

[aaronuconn]

Currently dosing preworkout:
2g ALCAR
2g Choline Citrate
200mg caffeine
25mg ephedrine
200mcg Huperzine


Currently loving it, but I was curious if there was anything you all would recommend adding?

That looks like a tremendous pre-workout stack. Energy and long lasting focus.

[itzDodge]

Currently dosing preworkout:
2g ALCAR
2g Choline Citrate
200mg caffeine
25mg ephedrine
200mcg Huperzine


Currently loving it, but I was curious if there was anything you all would recommend adding?

Could try playing around with theanine for focus and some bulk pump ingredients as well, like cit mal

[cjwav34]

Could try playing around with theanine for focus and some bulk pump ingredients as well, like cit mal

I mix it was 1g agmatine, and 488mg of potassium nitrate. I'm VERY happy with the pump/vascularity that gives me.

I will look into theanine. What kind of dosing should I play around with?

[itzDodge]

I mix it was 1g agmatine, and 488mg of potassium nitrate. I'm VERY happy with the pump/vascularity that gives me.

I will look into theanine. What kind of dosing should I play around with?

Gotcha, that should produce an awesome pump. Theanine dose between 100-200mg, should dull out the jitters of stimulants as well.

[cjwav34]

Gotcha, that should produce an awesome pump. Theanine dose between 100-200mg, should dull out the jitters of stimulants as well.

Will look into it for my next order.

[adrenalin18stud]

i've tried quite a few nootropics...

piracetam - exellent for memory and creativity and focus and but needs to be dosed higher than other racetams.
sulbutiamine - gave me a non-jittery focused energy boost and great mood lifter IMO the best alternative to dmaa that i've found so far, tastse horrible though.

L-theanine - i used this to come down off phenibut, is non addictive and has potent anti anxiety effects.
phenibut - great anxiety killer, mood lifter very simular to benzodiazepines.
picamilon - great for anti anxiety aswell, also gives me a great improvement in mood and focus.
Alcar - gives me energy and great focus and memory.
L-dopa - gives me great focus and lift in mood and energy
phenylethylamine - great focus at low doses and at high doses gives me a good euphoric buzz simular to ecxtacy.

this is what i've tried and loved them all, now i've had recent interest in aniracetam and pramiracetam at what dose is best to take these two and do they taste ok? should i cap them or is it ok to mix with juice or diet soda?(i did find bulk piracetam powder fine to be mixed with juice or pepsi)

thansks

[eatyourspinach]

Just wanted to thank everyone for the helpful insight I have received, thanks to the thread I decided to pick up some Prami with my latest purchase. Gotta order some more ALCAR any advice as if I should should pick up some Alpha GPC or Huperzine? I debating as to which one I know they are completely different things I just have a lot of choline citrate still but taking it at higher does kind of made me feel depressed where to lower dose of Alpha GPC was pleasant lol. Thanks again.

[xLGx]

El Oh El.

Come on meow

Any way to discredit this theory? Would PDE3 expression otherwise increase with rising cAMP levels while the PDE4 is inhibited?

[aaronuconn]

Just wanted to thank everyone for the helpful insight I have received, thanks to the thread I decided to pick up some Prami with my latest purchase. Gotta order some more ALCAR any advice as if I should should pick up some Alpha GPC or Huperzine? I debating as to which one I know they are completely different things I just have a lot of choline citrate still but taking it at higher does kind of made me feel depressed where to lower dose of Alpha GPC was pleasant lol. Thanks again.

If you already have the Choline Citrate, I would finish that up and go with Huperzine.

[gymrat53]

Will look into it for my next order.

where do you get potassium nitrate?

[cjwav34]

where do you get potassium nitrate?

[DannySampsonite]

Recently, nothing. I'm currently cycling off a lot of supplements right now, stims and ALCAR included. I just had 750mg caps and would take it in the morning. I even tried 750mg in the morning and another 750mg later in the afternoon.

CILTEP is a theory that's relatively new in which the ultimate goal is to increase cAMP molecules in the brain with 3 simple ingredients. First is Forskolin, which we all know increases cAMP. Since PDE4 receptors block cAMP in our brains, a PDE4 inhibitor supplement is needed (Artichoke Extract). If we inhibit our PDE4 receptors and increase our cAMP, the idea is we will be more attentive, energetic and productive and our memory capabilities should increase. The last ingredient is the icing on the cake and is meant to be a dopamine increaser. There are a lot of ways you can go about increasing dopamine levels, but a lot of people have had success with L-phenylalanine. Standard dosing protocol is something like:

- 500mg Artichoke Extract
- Forskolin (I've seen ranges from 4mg-20mg)
- L-Phenylalanine (I've seen ranges from 500mg-1,000mg)

I've yet to try it but my ingredients are en route (extremely cheap as well). I'll report in here when I get a grasp of the effectiveness of this stack. For what it's worth, my good friend tried it yesterday and said it was the best nootropic stack he has ever tried [and he has tried it all].

Phenylalanine is more upstream/regulated in dopamine production than both tyrosine and l-dopa. Why would you take phenylalanine?

Artichoke extract won't affect brain PDE4.

Regardless, the whole theory is dumbassery because one cannot accurately predict the cognitive effects of increasing cAMP, which is a molecule that is upstream to a whole host of different effectors depending on the brain region.

[Outside backer]

I have recently heard many good things about CILTEP

[gymrat53]

grazie

[cjwav34]

grazie

No problem.

195mg of potassium nitrate per 2 caps. On my second week, and just upped the dose to 5 caps. The vascularity I've seen has been the best I've ever had.

[gymrat53]

No problem.

195mg of potassium nitrate per 2 caps. On my second week, and just upped the dose to 5 caps. The vascularity I've seen has been the best I've ever had.

I like the sounds of that even though it reminds me of that awful wayne and drake song.

[aaronuconn]

I like the sounds of that even though it reminds me of that awful wayne and drake song.

Just Drake.

What's the upwards amount of Potassium Nitrate to consume before you run into some issues? (hypotension)

[ChrisLS8]

Around 750 to 1000 mg. Sometimes even as low as 500 mg

[xLGx]

Phenylalanine is more upstream/regulated in dopamine production than both tyrosine and l-dopa. Why would you take phenylalanine?

Artichoke extract won't affect brain PDE4.

Regardless, the whole theory is dumbassery because one cannot accurately predict the cognitive effects of increasing cAMP, which is a molecule that is upstream to a whole host of different effectors depending on the brain region.

Luteolin does, which is extracted from artichoke. It non-selectively inhibits PDE1-5.

L-Phenylalanine is just a conservative choice for someone just starting out on CILTEP since it's an amino acid that the body is already used to metabolizing to make dopamine. Should this not be enough for you, there are plenty of other supplements out there that can increase dopamine you can plug in as a replacement.

I have recently heard many good things about CILTEP

Same.

[gymrat53]

Just Drake.

What's the upwards amount of Potassium Nitrate to consume before you run into some issues? (hypotension)

I actually like Drake. Take Care is a good album, Thank Me Later, and his first mixtape as well. Old Wayne was good too he's a joke now though.

There is going to be a lot of interindividual variables to this. Start slowly and work up to see what you can handle, like cjwav said he is now on 5 which equates to 1250 of potassium nitrate