So the new USP Labs product VERSA-1 recently released the compound ingredients below.
Proprietary Blend 400 mg
N-[2-hydroxy-2(4-methoxyphenyl)ethyl]-3-phenyl-2-propenamide, Cytidine 5’-diphoscholine
As many people have already pointed out, the first compound listed is aegeline, which shows antihyperlipidemic, antihyperglycemic and antidyslipidemic properties in diabetic rat models. Also, it has been postulated to be a beta(3)-adrenergic receptor agonist as well. This is one of the ingredients in the new formulation of OEP, and certainly makes sense for inclusion in a weight loss formula and makes sense based on the results of leaning out that some users of VERSA-1 reported. However, it is the purported anabolic properties of OEP that I am more interested in. If you look at the third reference cited by USP Labs, they list Sharma et al., which is actually anacyclus pyrethrum. http://www.ncbi.nlm.nih.gov/pubmed/22473789
Following up on this, it seems more likely that this compound is responsible for the anabolic properties and lean mass gains reported by users in the test logs. Taken from the Sharma abstract:
Additionally, an earlier publication from 2010 from the same group (full study is available on pubmed here, http://www.ncbi.nlm.nih.gov/pubmed/20727332) demonstrated improved sexual behavior in male rats following an ethanol extract of anacyclus pyrethrum, but more interestingly, also demonstrated significant improvements in body weight and sexual organs (testes, prostate, seminal vesicles, and epididymides), similar to administration of testosterone. This led the authors to conclude that anacyclus had both anabolic and androgenic properties.Extract administration at all the doses produced significant increase in body weight, sperm count, motility, and viability along with serum testosterone, luteinizing hormone, and follicle-stimulating hormone concentrations... Our results suggest that the ethanol solution extract of the roots of A. pyrethrum has androgenic potential...
Now, while I'm not keen on the idea of an enlarged prostate, this does make this compound seem very interesting. But the question is then, is N-[2-hydroxy-2(4-methoxyphenyl)ethyl]-3-phenyl-2-propenamide found in anacyclus pyrethrum?
THEHUGE had experimented with anacyclus awhile back (http://forum.bodybuilding.com/showth...4866411&page=1), and I know that this is the ingredient in PES' Anabeta, which also generated a lot of buzz in the beginning, although I haven't heard much about it lately.
So I was curious to see what others thoughts were on this subject and whether anyone knows if aegeline is also found in extracts of anacyclus pyrethrum.