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alpha-Glycerylphosphorylcholine administration increases the GH responses to GHRH of young and elderly subjects.
Authors
Ceda GP,*et al.*Show all
Journal
Horm Metab Res. 1992 Mar;24(3):119-21.
Affiliation
Chair of Gerontology and Geriatrics, University of Parma, Italy.
Abstract
Growth hormone (GH) secretion is decreased during aging in humans and in rodents. This decrease may be due to increased hypothalamic ****tostatin release, which is inhibited by cholinergic agonists, or to decreased secretion of GHRH. Alpha-glyceryl-phosphorylcholine (alpha-GFC) is a putative acetylcholine precursor used in the treatment of cognitive disorders in the elderly. In order to learn what effect alpha-GFC had on GH secretion, GH-release hormone (GHRH) was given to young and old human volunteers, with or without the addition of alpha-GFC. GH secretion was greater in the younger subjects than in the old individuals, and both groups had a greater GH response to the GHRH+alpha-GFC than to GHRH alone. The potentiating effect of alpha-GFC on GH secretion was more pronounced in the elderly subjects. These findings confirm the observation that aged individuals respond less well to GHRH than younger subjects, and provides further evidence that increased cholinergic tone enhances GH release.
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Thread: Alpha-Glycerylphosphorylcholine
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01-05-2013, 04:26 PM #1
Alpha-Glycerylphosphorylcholine
100% natural and proud of it! (No PH's,DS's,AAS, etc.)
From 135 lbs to 227 lbs (naturaly and with severe obstructive sleep apnea)
Even with poor sleep you can gain thanks to quality food and good workout plan
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01-05-2013, 04:30 PM #2
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01-05-2013, 04:33 PM #3
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01-05-2013, 04:33 PM #4
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01-05-2013, 04:36 PM #5
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01-05-2013, 04:38 PM #6
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01-05-2013, 04:42 PM #7
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01-05-2013, 04:48 PM #8
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01-05-2013, 04:51 PM #9
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01-05-2013, 04:52 PM #10
there is a more recent one and that only increased gh to 4 ng/ml. Pretty ghay. I could do 2 jumping jacks to hit that.
http://www.ncbi.nlm.nih.gov/pubmed/22673596
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01-05-2013, 04:53 PM #11
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01-05-2013, 04:54 PM #12
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01-05-2013, 05:02 PM #13
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