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  1. #1
    Registered User mike990's Avatar
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    Creatine increases DHT possibly. What are the effects of this?

    Should I be worried by this increase in DHT? I've looked through pubmed for effects of DHT.

    Increases aggression/antisocial behavior
    Improve sex life
    Causes reversible testicular atrophy
    Increase acne, body hair
    Hair loss
    Reduce estrogen
    Up-regulates the gene expression of hypocretin (also called orexin), pro-melanin-concentrating hormone, and protein kinase C delta.
    Increases hemoglobin

    There are 71 hormones in the human body. I'm not searching for the effects of DHT on these, as it would take hours.
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  2. #2
    ASSFUKKER6969 thefleshlight's Avatar
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    Talk about over-analysis.
    Even if you're right about a noticeable increase in DHT, I'm sure it won't affect you as much as, say pinning test and tren.
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  3. #3
    Registered User jms1281's Avatar
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    He went on pubmed... the only people that look things up on pubmed are psychosomatics and hypochondriacs. Creatine is naturally produced by the body captain einstein
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    Mike, it's possible that some people experience those side effects. I'm not an expert on the potential side effects, but maybe someone with knowledge about the creatine/DHT relationship will chime in.
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  5. #5
    Get Diesel Or Die Trying Younglifter16's Avatar
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    this study again? it was done on like a dozen guys, some showed a spike in DHT when the creatine was LOADED (20+ grams a day), and the DHT was stabalized when they went down to a normal dose (aka 3-5 grams a day). Nothing to see here.
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  6. #6
    Banned AENShill's Avatar
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    Originally Posted by Younglifter16 View Post
    this study again? it was done on like a dozen guys, some showed a spike in DHT when the creatine was LOADED (20+ grams a day), and the DHT was stabalized when they went down to a normal dose (aka 3-5 grams a day). Nothing to see here.
    Sometimes, it doesn't hurt to ask "why?" Wouldn't you like to know why loading creatine spikes DHT? I sure as hell would.
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  7. #7
    Get Diesel Or Die Trying Younglifter16's Avatar
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    Originally Posted by AENShill View Post
    Sometimes, it doesn't hurt to ask "why?" Wouldn't you like to know why loading creatine spikes DHT? I sure as hell would.
    nothing wrong with asking what a study means or entails, but we've had countless threads (some even in this sub section alone) about this study.
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  8. #8
    Banned AENShill's Avatar
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    Originally Posted by Younglifter16 View Post
    nothing wrong with asking what a study means or entails, but we've had countless threads (some even in this sub section alone) about this study.
    But in all those threads, the people just point out the methodology without addressing the "why." Sometimes, we need these irrelevant studies to understand relevant endpoints.
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  9. #9
    Registered User mike990's Avatar
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    Originally Posted by Younglifter16 View Post
    this study again? it was done on like a dozen guys, some showed a spike in DHT when the creatine was LOADED (20+ grams a day), and the DHT was stabalized when they went down to a normal dose (aka 3-5 grams a day). Nothing to see here.
    It wasn't stabilised, it went down from 56% to 40%. I accept that a 40% increase is not the 6-700% increase that a DHT injection causes.

    I still think it is reasonable to assume that some of these side effects should occur. I will take creatine regardless.
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  10. #10
    Registered User mike990's Avatar
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    The testicular atrophy doesn't happen, as creatine doesn't reduce testosterone.

    Also, it increases DHT:T ratio which makes you a homo - http://www.ncbi.nlm.nih.gov/pubmed/15677419

    DHT doesn't cause hair loss, 5-ar does.

    So whats left is

    Increase acne, body hair
    Increases aggression/antisocial behavior
    Improve sex life
    Reduce estrogen
    Up-regulates the gene expression of hypocretin (also called orexin), pro-melanin-concentrating hormone, and protein kinase C delta.
    Increases hemoglobin
    Homosexuality

    There are 71 hormones in the human body. I'm not searching for the effects of DHT on these, as it would take hours.
    Last edited by mike990; 12-10-2012 at 08:53 AM.
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  11. #11
    Registered User DR_P's Avatar
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    Cool

    Haha, some serious trolling in the supp science section.

    Originally Posted by mike990 View Post
    The testicular atrophy doesn't happen, as creatine doesn't reduce testosterone.

    Also, it increases DHT:T ratio which makes you a homo - http://www.ncbi.nlm.nih.gov/pubmed/15677419

    DHT doesn't cause hair loss, 5-ar does.

    So whats left is

    Increase acne, body hair
    Increases aggression/antisocial behavior
    Improve sex life
    Reduce estrogen
    Up-regulates the gene expression of hypocretin (also called orexin), pro-melanin-concentrating hormone, and protein kinase C delta.
    Increases hemoglobin
    Homosexuality

    There are 71 hormones in the human body. I'm not searching for the effects of DHT on these, as it would take hours.
    ThermoLife scientific consultant
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  12. #12
    Banned citrullination's Avatar
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    Originally Posted by DR_P View Post
    Haha, some serious trolling in the supp science section.
    The best part is how increasing DHT makes you a homo.
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  13. #13
    Registered User DR_P's Avatar
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    IMHO, it might not be totally off that hormonal imbalances during brain *development* (=during embryonal, fetal and infant stages) could somehow be involved in setting the course for future sexual orientation. However, proposing that a shot of DHT in male ADULTS would change someone's sexual orientation is utter nonsense. The paper that the OP referenced only talks about correlations and not about causality. Actually, most of the OTC prohormones sold in the past recent years have been based on DHT derivatives. If OP's theory was right, everyone who had been taking superdrol etc. should have turned gay.


    Originally Posted by citrullination View Post
    The best part is how increasing DHT makes you a homo.
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  14. #14
    Registered User mike990's Avatar
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    So whats left is

    Increase acne, body hair
    Increases aggression/antisocial behavior
    Improve sex life
    Reduce estrogen
    Up-regulates the gene expression of hypocretin (also called orexin), pro-melanin-concentrating hormone, and protein kinase C delta.
    Increases hemoglobin

    There are 71 hormones in the human body. I'm not searching for the effects of DHT on these, as it would take hours.
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  15. #15
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    Originally Posted by DR_P View Post
    IMHO, it might not be totally off that hormonal imbalances during brain *development* (=during embryonal, fetal and infant stages) could somehow be involved in setting the course for future sexual orientation. However, proposing that a shot of DHT in male ADULTS would change someone's sexual orientation is utter nonsense. The paper that the OP referenced only talks about correlations and not about causality. Actually, most of the OTC prohormones sold in the past recent years have been based on DHT derivatives. If OP's theory was right, everyone who had been taking superdrol etc. should have turned gay.
    I agree, though even the development theory has correlations that do and don't match up. It's certainly a complex beast.
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