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  1. #1
    Banned lemonadedildow's Avatar
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    Vitamin D3 oversupplementation... Heart problems?

    Okay, so I've read tons about how D3 is suppose to help with cancer, heart problems, etc... Sounded, too good to be true.. I ran into a study where rats given a lot of D3 actually had cardiac necrosis, and died... Pretty scary? I also found another study dealing with chicken broilers... Pretty much same thing happened, heart problems > death..

    Here is the study on Vitamin D3 on rats causing cardiac necrosis. They were given 100,000 IU, 3x a day, for only 3 days? I know rats metabolism works different, how much would this be equivalent to in a human? Any guess?
    http://www.sciencedirect.com/science...b&searchtype=a

    Here is full PDF
    http://www.google.com/url?sa=t&sourc...zgnD6w&cad=rja

    Here is the one on chicken broilers
    http://www.sciencedirect.com/science...c&searchtype=a

    Sorry for the long, stupid URL's ... Don't know how to shorten.


    Here is a google search for vitamin d3 being good for the heart
    http://www.google.com/#sclient=psy&h...2bf32b5c0e0691

    Scary? I was going to take 50,000 IU twice a week for so called "benefits", now I'm scared to touch this stuff...
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  2. #2
    SimplyShreddedTV Valenzuelatech's Avatar
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    300,000 IU is a ridiculously high dosage of cholecalciferol for human consumption, exponentially more so for a rodent given the difference in body mass.
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  3. #3
    Registered User _Smitty_'s Avatar
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    Originally Posted by Valenzuelatech View Post
    300,000 IU is a ridiculously high dosage of cholecalciferol for human consumption, exponentially more so for a rodent given the difference in body mass.
    ridiculous is an appropriate descriptor considering it's fat soluble and the unusable excess is stored.
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  4. #4
    Polski Bro mobikwa's Avatar
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    I ran a similar study, I supplemented 10,000 gallons of water per day for 3 days to 5 otherwise healthy individuals. They all did, indeed, died. There you have it folks, water will kill you.
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  5. #5
    BioX Nutrition Rep andrewwww's Avatar
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    Originally Posted by _Smitty_ View Post
    ridiculous is an appropriate descriptor considering it's fat soluble and the unusable excess is stored.
    im usually intaking 6000-8000iu per day is that safe?
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  6. #6
    Why so serious? Yates Row T's Avatar
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    Originally Posted by andrewwww View Post
    im usually intaking 6000-8000iu per day is that safe?
    more than likely that is just fine. ever had ur 25-OH drawn?


    I was supplementing with 8000iu/day and my 25-OH just came back LOWER. i was at 66, then dropped to 58 NOW 50.

    Makes no sense. Upped to 12000iu/5x/week
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  7. #7
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    This is over sharing, but I noticed that when I had too much vitamin d3, i had....bowel problems.
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  8. #8
    Are you Driven? Sldge's Avatar
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    Originally Posted by andrewwww View Post
    im usually intaking 6000-8000iu per day is that safe?
    Until you are out in the sun regularly that is definitely fine. 5000-10000 is going to be a good amount for most people.
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