From Dirk (our product formulator)
Couple quick reads on how the Lit-Up formula negates any type of potential side effects from D-Aspartic Acid:
http://ceu-usa.com/courses/WC001/tes...tion_cycle.htm
http://hopes.stanford.edu/n3619/drug...ion/folic-acid
http://www.chronicfatiguetreatments....igue-syndrome/
This is why some people get depressed or anxious on regular DAA products- DAA activates the NMDA receptor, and NMDA activation, while ok in itself, is not good in excess. When homocysteine begins to build up (it is a by-product in the SAM-e cycle), it can actually cause additional excess activation in the NMDA receptor. This can lead to a lot of the sides you are hearing about from DAA, such as anxiety, depression, and night sweats. However, homocysteine has two routes of disposal- and this is the beauty of the formulation:
1. It can accumulate and be disposed of in the urine
2. It can be transformed (re-methylated) into methionine by folic acid, where it can re-enter the SAM-e cycle and be used again.
As you can see in the articles, Folate, TMG, and B-12, are all substrates that help to increase step 2- and this is why you will never see any DAA-related sides from Lit-Up- the product contains agents that re-methylate homocysteine, thus preventing any type of build-up in the tissues and keeping it from overloading the NMDA receptor....
Probably the best way to measure it is by how you feel- if you are anxious, depressed, and have trouble sleeping when you are taking DAA, you probably are getting some overstim on the NMDA receptor, and need some methylating agents to recycle the excess homocysteine. DAA plus methylating agents has a different "feel" to it- you feel up and energetic all the time, with a huge libido boost.....
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