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    Tamoxifen and Gynecomastia (srs)

    I'm considering take Tamoxifen to get rid of my slight case of gynecomastia.

    Has anyone seen good results from using it?

    *I'm a little worried after reading the side effects too. Do those mostly apply to people using it over a long period of time?

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    Originally Posted by DB791 View Post
    I'm considering take Tamoxifen to get rid of my slight case of gynecomastia.

    Has anyone seen good results from using it?

    *I'm a little worried after reading the side effects too. Do those mostly apply to people using it over a long period of time?
    You cycling bro? I'd say try letro first.
    It's consistency. It's like building a house. Everyday I'm putting a brick on my wall.

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    Originally Posted by Rattlehead18 View Post
    You cycling bro? I'd say try letro first.
    LOL. Just using it to get rid of the gyno.

    My brother used Tamoxifen and Letro, but said Letro didn't work for him.

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    tamoxifen doesnt remove pre-existing gyno.
    “Foolish and wretched is the man who builds his happiness on the frail and unstable affection of a woman.”

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    Registered User Jag3034's Avatar
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    Doubt it will do much to pre-existing gyno, letro would be better for that.
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    Originally Posted by Wisdom187 View Post
    tamoxifen doesnt remove pre-existing gyno.
    It did for my brother. His nipples are completely flat now.

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    Originally Posted by Wisdom187 View Post
    tamoxifen doesnt remove pre-existing gyno.
    o'rly?

    Metabolism. 1986 Aug;35(8):705-8.
    Treatment of gynecomastia with tamoxifen: a double-blind crossover study.

    Parker LN, Gray DR, Lai MK, Levin ER.
    Abstract

    Benign asymptomatic or painful enlargement of the male breast is a common problem, postulated to be due to an increased estrogen/testosterone ration or due to increased estrogenic or decreased androgenic stimulation via estrogen or androgen receptor interactions. Treatment at present consists of analgesic medication or surgery. However, treatment directed against the preponderance of estrogenic stimulation would seem to represent a more specific form of therapy. In the present double-blind crossover study, one-month courses of a placebo or the antiestrogen tamoxifen (10 mg given orally bid) were compared in random order. Seven of ten patients experienced a decrease in the size of their gynecomastia due to tamoxifen (P less than 0.005). Overall, the decrease for gynecomastia for the whole group was significant (P less than 0.01). There was no beneficial effect of placebo (P greater than 0.1). Additionally, all four patients with painful gynecomastia experienced symptomatic relief. There was no toxicity. The reduction of breast size was partial and may indicate the need for a longer course of therapy. A followup examination was performed in eight out of ten patients nine months to one year after discontinuing placebo and tamoxifen. There were no significant changes from the end of the initial study period except for one tamoxifen responder who developed a recurrence of breast tenderness after six months, and one nonresponder who demonstrated an increase in breast size and a new onset of tenderness after ten months. Therefore, antiestrogenic treatment with tamoxifen may represent a safe and effective mode of treatment for selected cases of cosmetically disturbing or painful gynecomastia.

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    letro is the strongest stuff you can use, he's bull****ting

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    Originally Posted by Wisdom187 View Post
    tamoxifen doesnt remove pre-existing gyno.
    was gonna say this. tamo and nolva could rid you of slight puffiness but once gyno has set in you have a slight chance of letro working then surgery is the only other option

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    Originally Posted by DB791 View Post
    LOL. Just using it to get rid of the gyno.

    My brother used Tamoxifen and Letro, but said Letro didn't work for him.
    letro was probably bunk. Real letro is pretty expensive. Having said that, the main problem with non-steroid AI's is rebound upon cessation of use. SERM's are better for gyno. Don't listen to the broscience in this thread.

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    Originally Posted by DB791 View Post
    It did for my brother. His nipples are completely flat now.
    he most likely didn't have gyno then. true gyno will cause the glands behind the nipple to get hard. you will notice the difference. before this happens there is a period of time where the nipple is just puffy. this can just be bodyfat but it could also be the beginning stages of gyno. letro, nolva, or tamo can fix this. once it's hard though it's surgery time.

  12. #12
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    Off topic. Does arimidex reduce gyno, or is it just a preventative thing?
    It's consistency. It's like building a house. Everyday I'm putting a brick on my wall.

  13. #13
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    I used to think I had gyno, but it turns out my body stored fat around the chest. Most people crying about gyno just have excess body fat on these forums.

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    Originally Posted by germanyt View Post
    he most likely didn't have gyno then. true gyno will cause the glands behind the nipple to get hard. you will notice the difference. before this happens there is a period of time where the nipple is just puffy. this can just be bodyfat but it could also be the beginning stages of gyno. letro, nolva, or tamo can fix this. once it's hard though it's surgery time.
    this.

    I doubt you have real gyno, just puffyness. Its merely your hormones trying to find a balance, until it begins to hurt, is evident at <8% bf or hardens its not a real concern. I was convinced I had gyno at 20 as well; I didn't just puffiness and some extra bodyfat going to the wrong place.

    edit: got ninjaed by the above me.

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    Originally Posted by aspire210 View Post
    this.

    I doubt you have real gyno, just puffyness. Its merely your hormones trying to find a balance, until it begins to hurt, is evident at <8% bf or hardens its not a real concern. I was convinced I had gyno at 20 as well; I didn't just puffiness and some extra bodyfat going to the wrong place.

    edit: got ninjaed by the above me.
    My nipples are pretty sensitive though.
    So do you think it could just condensed fat from your experiences?

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    Originally Posted by DB791 View Post
    My nipples are pretty sensitive though.
    So do you think it could just condensed fat from your experiences?
    SWIM (someone who isn't me) once used cell-tech and it caused nipples to be so sore it hurt to take their shirt on and off. Upon cessation of said cell-tech, it stopped. Point is, its not just sensitive, its down right pain. When I was 20 I stored more fat there, as time has gone on, I store less.

    Basically, you are making tons of testosterone right now. In a nutshell, more test = more estrogen, more estrogen = puffy nipples and storing more body fat there. Over time, your body will find a set point and it will go away. Unless it gets to the point of discharge/true pain I would ignore it. No point in messing with your endocrine system. Also, leave them alone. Constant touching will cause them to get irritated and may result in a weird clear discharge that is indicative of nothing, but will mess with your head.

  17. #17
    Pussy Liquor Wisdom187's Avatar
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    Originally Posted by aspire210 View Post
    o'rly?

    Metabolism. 1986 Aug;35(8):705-8.
    Treatment of gynecomastia with tamoxifen: a double-blind crossover study.

    Parker LN, Gray DR, Lai MK, Levin ER.
    Abstract

    Benign asymptomatic or painful enlargement of the male breast is a common problem, postulated to be due to an increased estrogen/testosterone ration or due to increased estrogenic or decreased androgenic stimulation via estrogen or androgen receptor interactions. Treatment at present consists of analgesic medication or surgery. However, treatment directed against the preponderance of estrogenic stimulation would seem to represent a more specific form of therapy. In the present double-blind crossover study, one-month courses of a placebo or the antiestrogen tamoxifen (10 mg given orally bid) were compared in random order. Seven of ten patients experienced a decrease in the size of their gynecomastia due to tamoxifen (P less than 0.005). Overall, the decrease for gynecomastia for the whole group was significant (P less than 0.01). There was no beneficial effect of placebo (P greater than 0.1). Additionally, all four patients with painful gynecomastia experienced symptomatic relief. There was no toxicity. The reduction of breast size was partial and may indicate the need for a longer course of therapy. A followup examination was performed in eight out of ten patients nine months to one year after discontinuing placebo and tamoxifen. There were no significant changes from the end of the initial study period except for one tamoxifen responder who developed a recurrence of breast tenderness after six months, and one nonresponder who demonstrated an increase in breast size and a new onset of tenderness after ten months. Therefore, antiestrogenic treatment with tamoxifen may represent a safe and effective mode of treatment for selected cases of cosmetically disturbing or painful gynecomastia.
    that has nothing to do with pre-existing hard lumps. those wont go away without surgery. Tamoxifen citrate is a catch-mid-gyno type thing and a preventative.

    its not going to make hard lumps in your tits disappear.
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    Originally Posted by Wisdom187 View Post
    that has nothing to do with pre-existing hard lumps. those wont go away without surgery. Tamoxifen citrate is a catch-mid-gyno type thing and a preventative.

    its not going to make hard lumps in your tits disappear.
    OP says "slight case of gyno."

    Also, nothing will make hard lumps disappear, not letro either. Surgery is only option at that point for complete removal, but studies have shown 50-80% reduction in diameter with tamox. Also, introducing letro into a endocrine system that is already slightly off without titration could lead to rebound issues.

    lulz mad I disproved your broscience?

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    puffy nipples; is that a symptom of gynecomastia?

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    Originally Posted by Wisdom187 View Post
    tamoxifen doesnt remove pre-existing gyno.
    this^

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    90% of people who think they have gyno are just in denial of their high body fat percentage.
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    Originally Posted by Wisdom187 View Post
    tamoxifen doesnt remove pre-existing gyno.
    Originally Posted by germanyt View Post
    was gonna say this. tamo and nolva could rid you of slight puffiness but once gyno has set in you have a slight chance of letro working then surgery is the only other option
    these

  23. #23
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    Originally Posted by aspire210 View Post
    OP says "slight case of gyno."

    Also, nothing will make hard lumps disappear, not letro either. Surgery is only option at that point for complete removal, but studies have shown 50-80% reduction in diameter with tamox. Also, introducing letro into a endocrine system that is already slightly off without titration could lead to rebound issues.

    lulz mad I disproved your broscience?
    what did you disprove? you agreed with me dumbass.
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  24. #24
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    Originally Posted by Wisdom187 View Post
    what did you disprove? you agreed with me dumbass.
    lulz my bad brahski, guy below u said letro removes it.

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    take letro, my friend has had a few cycles as iv said in other threads

    no gyno and gyno that was there (or small stored fat) is now gone

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    Originally Posted by aspire210 View Post

    I doubt you have real gyno.
    I see this crap all the time. Gyno, by definition, is literally "female-looking breasts". Gyno is purely subjective.... unlike cancer. Maybe people that can show me "real gyno" could also describe a "real vampire" to me.

    If a cheetoh somehow slipped under your chest, causing it to stick out, one person might say that is gyno.

    I think what most people refer to as "real gyno" is overdeveloped glandular breast tissue. All males have glandular breast tissues... but most males would not be considered to have gyno. Once this mass gets to a certain size, it changes the shape of the chest... usually making the nips stick out... some people might call this gyno.

    I think the most important thing before making a bro-diagnosis and recommending strong pharmaceuticals on BB.com is seeing whether or not the guy has symptoms of glandular growth. If he just prone to store adipose tissue on his chest, letro would be useless and could actually cause glandular growth if not administered correctly.

  27. #27
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    I would not recommend tamox for nandrolone induced gyno if that is the case. There is enough enough evidence to suggest the upregulation progesterone receptors with its use...not conducive for such compounds.

    If you can get Raloxifene then I would use that.
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    two questions:

    1) if the op takes letro won't that screw up his lipid profile?
    2) is it true that a side effect of using letro or nolva is blindness?
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    Originally Posted by panic91984 View Post
    I would not recommend tamox for nandrolone induced gyno if that is the case. There is enough enough evidence to suggest the upregulation progesterone receptors with its use...not conducive for such compounds.

    If you can get Raloxifene then I would use that.
    in the case of progesterone induced gyno, which by the way is pretty rare, something like RU-486 aka the abortion drug is a much better idea. Of course if hes using tren and its prolactin based, then maybe dostinex would be a better idea. Then again, he specifically said he doesn't use any form of cell-tech so these aren't even relevent.

    Originally Posted by metallideth View Post
    two questions:

    1) if the op takes letro won't that screw up his lipid profile?
    2) is it true that a side effect of using letro or nolva is blindness?
    1) depends on dosage of letro
    2) possible, but very, very unlikely at reasonable dosage.


    PS I wouldn't get medical advice on the misc. This is all free advice and likely worth as much.

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    Originally Posted by panic91984 View Post
    I would not recommend tamox for nandrolone induced gyno if that is the case. There is enough enough evidence to suggest the upregulation progesterone receptors with its use...not conducive for such compounds.

    If you can get Raloxifene then I would use that.
    who mentioned deca?

    im pretty sure op said he's not using anything.

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