Best Liver Support

[Buckobucko]

What is the Best liver support you have tried?

[koard31]

Guinness makes my liver happy.

[jamestyk]

What is the Best liver support you have tried?

Liv.52

[2ripp3dup]

liv 52 or liver longer

[Loffs919]

vodka...straight vodka

[JohnSmeton]

If you are asking because you want to do hormones I recommended you wait until you are at least mid twenties, get your diet, training and recovery in order though sleep, power naps and supplementation.

You have all the test in the world running though your veins right now take advantage of it. If you use hormones you can mess that up for life where they'll be suppressed and never reach your optimal levels. That is why I say at least wait until mid twenties and even then that is a big choice.

with that said, my best liver support supplement is cycle support

[COUNTRYMIKE]

"Liver Fix" from MYOGENIX is awesome, I really like this product alot.

[MustangManGT]

I just started Nature' Science Milk Thistle, got it off this site, they a special buy 1 get 1 free right now. Can't tell you about it yet since I just started it yesterday, but its gotten pretty good reviews.

[Amino89]

Single ingredient: NAC
Designer product: Cycle Support (orange) or Life Support.

[NO HYPE]

What is the Best liver support

You want a 3-step solution for a clinically effective hepatopatoprotective combo?

NAC/SAMe/Na-RALA

[huge908]

NAC, get some milk thistle, and than some SAMe. those three are the ones I can recommend. Or jsut Liv52.

[Surive123]

"Liver Fix" from MYOGENIX is awesome, I really like this product alot.

Glad you like it!

[liv2pb]

every three months i do an organic total body cleanse by RenewLife
its over 30 days so its not harsh on the system

[youngt]

liver longer

[androo_k]

By far the best liver support. Over 200 clinical peer reviewed studies backing it up. Hell even helps with hangovers LOL Does everything Milk Thistle dose and more and has no contraindications with drugs.

[NO HYPE]

...

[NO HYPE]

By far the best liver support.

Not true, and the 200 studies you referenced do not conclude that either. While being a truly beneficial hepatoprotectant.... Liv-52 is not going to elicit protection anywhere near the degree that NAC and/or SAMe can.

EDIT: I should rightfully add TUDCA, Na-RALA and PPC to the list as well.

You want a 5-step solution for a clinically proven/effective hepatopatoprotective combo?

--> NAC/SAMe/TUDCA/Na-RALA/Polyenephosphatidylcholine

[2high2die]

Liver Juice /thread

[cmagdy119]

For years steroid users have been taking Milk Thistle (Silybum marianum, which contains the polyphenolic flavonoid silymarin and the active component silibinin) to protect their livers from potentially hepatoxic oral steroids. In the Anabolics series of books, William Llewellyn talks about using this stuff as a liver protector. Well, he’s wrong…yeah, it’ll protect your liver, but it’s also going to reduce the effectiveness of the entire cycle, by reducing androgen receptor transactivation and also by inhibiting the IGF-I signaling pathway.
Less androgen receptor activity + less IGF-1 = less muscle and strength.


MuscleTech uses milk thistle in some of their products as does Universal (it’s in their Animal Pack and some others), as does Muscle Pharm and MHP (included it in a product designed to boost testosterone). Anabolic Innovations includes Milk Thistle in a product called “Cycle Support“- so clearly this stuff is being marketed heavily towards steroid users. Llewellyn even includes it in his “Liver Stabil” product….but users will pretty quickly find out that it’s making them gain less muscle and strength.
In any case, I’ve never been a fan of this kind of thing, i.e. taking one thing to stop side effects from another…robbing Peter to pay Paul, or Ringo or whatever…. To my way of thinking, if your dose is too high, it’s too high, and adding another chemical into the mix (herbal or not), is not the solution. Sure, you can take a ton of steroids with liver protectors and anti-estrogens and all kinds of other stuff…but why wouldn’t you just cut the dose down and not take all the other crap?
Effects of SM and SB on whole cell AR levels (a), transcription activity of the AR promoter (b) and ligand-binding activity of the AR (c). The upper panel in (a) shows a representative western blot analysis of total AR protein levels in LNCaP cells and Ponceau S staining, representing protein loading. The lower panel in (a) is a densitometric analysis of total AR protein levels from three independent experiments.

We know that estrogen is necessary for optimal growth, so why would we mega-dose on steroids, but then take an anti-estrogen with them? Our gains will effectively be reduced in a similar way to simply taking a lower dose – which would obviously cost less (the savings from lowering the dose + not buying the anti-estrogen). Using a lower (non-side effect causing) dose seems to make more sense (or using non-aromatizing androgens). So why would we take a ton of (potentially toxic) oral steroids with a liver protector? What if I could make the case that taking a liver protector (*in this case, Milk Thistle) will actually cause your entire cycle to be less effective?
I’ve been doing some research into Milk Thistle recently, because it’s the most commonly used liver protector for steroid users. It’s sold at GNC, Vitamin Shoppe, etc…and it not only works to protect the liver, it’s also pretty cheap. For years, mediocre supplement designers have been slamming this stuff into any formula that could be liver toxic, and then forgetting about it. It’s a no-brainer (literally). People just cram the stuff in their supplements without doing any real research.
The problem with Milk Thistle is that it inhibits certain functions within your androgen receptors, thereby making the steroids (androgens) you’re taking less effective – this is why it has been studied as a possible chemoprotective agent for androgen dependent cancers. The active component in Milk Thistle effectively reduces nuclear androgen receptor levels (click for the full study), and down-regulates several androgen-regulated genes primarily by inhibiting the transactivation activity of the AR, and can also inhibit nuclear localization of the androgen receptor. Admittedly this study only looks at certain site-specific androgen receptor cells, in certain situations, but I see no reason in the available data to think these effects wouldn’t be the case elsewhere.
I’ve also looked at several related studies, and I think that this stuff simply isn’t the best choice for liver protection. I’m not saying “don’t ever protect your liver with a supplement” – I’m saying find something other than Milk Thistle, ok? And lower the f*cking dose, or don’t use orals (like me) if you think you’re going to damage your liver. With the available information on Milk Thistle, why continue using the stuff? Certainly we know there are other things that protect the liver, and if we have reliable evidence that strongly suggests against Milk Thistle being ideal, then we shouldn’t be using it. Again, I’m not saying “don’t ever use anything to protect your liver” – I’m just arguing against this one product because I think it’s less than ideal for steroid users.
In fact, there is additional information available that strongly suggests that Milk Thistle will also have an inhibitory effect on the insulin-like growth factor I receptor-mediated signaling pathway. All in all, there seems to be a reasonable expectation that this stuff is anti-anabolic. Lowering IGF-1 is important for treating cancer, which makes Milk Thistle a promising compound in that field.
Uncle Chop-Chop

Nobody is right all of the time, and I’ve probably thought this stuff was a good idea in the past, and even recommended it (like Llewellyn and a lot of other people), but the truth is that Milk Thistle looks like an extremely bad idea for use on a cycle – at least if you want your cycle to be as effective as possible. I know that these studies aren’t perfect (i.e. they don’t examine healthy, weight training individuals, using steroids, etc…), but I’m still reasonably confidant that Milk Thistle will inhibit your gains from a cycle, and that’s the bottom line. I don’t know how much. Maybe a little. Maybe a lot. Either way there’s better choices out there, and no, I don’t sell a liver-support product, and no I don’t have a vested interest in bashing Milk Thistle…nor am I saying not to protect your liver (because if your liver gets destroyed, you’ll die). I’m just saying that this shouldn’t be your first choice (or any choice, really).

http://www.anthonyroberts.co.za/2010...gen-receptors/

[NO HYPE]

Liver Juice /thread

lol.

[w_llewellyn]

Milk Thistle is an excellent liver support ingredient, well tested with a very long history of use. Bodybuilders specifically have been using it and prescription silymarin products for a pretty long time now. I've never seen any indication they will interfere with, let alone substantially hinder, muscle gains. Sometimes you can read too far into clinical studies - place too much emphasis on what may be minor reactions or effects.

Liv-52 is a great product, and Essentiale Forte is good also. Both are inexpensive. I formulated Liver Stabil to be somewhat of a cross between these two, along with milk thistle and additional glutathione support ingredients. So long as you are taking something though, you probably won't go wrong. Serious liver toxicity is admittedly rare, but I still think there is value to supporting liver health. This organ has a central role in virtually all metabolic processes.

I can, however, see arguments that you can get away without using these supplements if they aren't in the budget.

[cmagdy119]

Milk Thistle is an excellent liver support ingredient, well tested with a very long history of use. Bodybuilders specifically have been using it and prescription silymarin products for a pretty long time now. I've never seen any indication they will interfere with, let alone substantially hinder, muscle gains. Sometimes you can read too far into clinical studies - place too much emphasis on what may be minor reactions or effects.

Liv-52 is a great product, and Essentiale Forte is good also. Both are inexpensive. I formulated Liver Stabil to be somewhat of a cross between these two, along with milk thistle and additional glutathione support ingredients. So long as you are taking something though, you probably won't go wrong. Serious liver toxicity is admittedly rare, but I still think there is value to supporting liver health. This organ has a central role in virtually all metabolic processes.

I can, however, see arguments that you can get away without using these supplements if they aren't in the budget.

I'm actually taking milk thistle, just came accross that post so i shared with you guys, maybe there was extra info on it.

[javier011]

every three months i do an organic total body cleanse by RenewLife
its over 30 days so its not harsh on the system

Hello,
can you tell me what is the progress with this, any side effect, any harm?
I am starting the 40's, and have taken many things when younger, now I have some problems with my health, I dont really know exactly, but I think I need to detoxify really.
Do you recommend me this 'Organic Total Body Cleanse' ??

thank you!