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  1. #1
    Registered User XMarineRunner's Avatar
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    Exclamation Use of L-Arginine without getting Cold Sores

    Hello all,

    I have searched and searched for an answer to this question, but have been unable to find one that is satisfactory:

    I have used Arginine in one form or another as a pre-workout supplement many times. I love it. Currently my favorite pre-workout supp is NO-Explode. However, it never fails... I use the supplement with Arginine and within a couple of days I have cold sores.

    Now, we all know that Arginine is required for replication of the HSV, therefore causing the cold sore. However, what we don't know (or rather what I don't know) is how to reap the benefits of the amino while mitigating the negative side effects.

    My thought here has to do with timing. I would like to know the timing required to pull off the following:

    1. Blood must be relatively low on lysine to allow for arginine to enter bloodstream.
    2. Take Arginine Supplement and allow it to enter bloodstream for working out and remain in bloodstream for an optimal time period.
    3. Take lysine supplement within an appropriate time period to shift the balance back in favor of the lysine to prevent getting a cold sore.
    4. Rinse / repeat

    Does anyone have any knowledge on this front or perhaps know of another way to get similar results without the Arginine?
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  2. #2
    Registered User mark0s's Avatar
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    Had to bump this thread..

    I was wondering the same question. I bought some product with arginine in it and love how it works, but it is causing me to break out in cold sores.

    I am aware that lysine is great for extinguishing the sores, but will the lysine I take counteract the arginine?

    If i take the prework out stuff before my workout, then take my protein after my workout with extra lysine, will that help?

    any help would be great, especially if anyone has tried anything like this.

    thanks.
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  3. #3
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    Valtrex might help

    valtrex.com/coldsores/cold_spread.html
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  4. #4
    Registered User Dan2riv2's Avatar
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    Lysine (might be spelled wrong) works for cold sores. My wife and I get them and have been using this for years. You can buy the lip balm or you can buy pill form. The pill is what I use and she uses the lip balm becuase she said it works better. We havent gotten cold sores for sometime now. hope this helps!!!

    No it wontcounter anything you take. I have been taking supps for years and nothing seemed not to work.
    Last edited by Dan2riv2; 02-28-2010 at 08:09 PM. Reason: forgot to add
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  5. #5
    10 30 10 shadar's Avatar
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    Just as an aside, L-Arg is crap for pre-workout performance and/or gains. But then the OP also likes No Xplode a lot... so I guess liking L-Arg as well makes sense, heh.
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  6. #6
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    lysine!! i bought bulk lysine (1,000g) and i have a few grams a day. problem solved! i add it to my protein shakes.
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  7. #7
    Registered User bmallen1's Avatar
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    Originally Posted by XMarineRunner View Post
    Hello all,

    I have searched and searched for an answer to this question, but have been unable to find one that is satisfactory:
    I've searched for an answer to this same question. I'm currently taking Muscle Pharm Assault which has an L-Arginine blend. I'm on my second container and I've definitely experienced what you're going through. I'm looking into finding an alternative preworkout supplement that doesn't have or at least doesn't have as much arginine. I also recently started taking an anti viral medication and it helped the initial cold sore i had go away but then a week after healing I start to get another. It sucks.

    But, for when you do have one, use Abreeva, use alcohol or peroxide with a q-tip, take lysine orally. Avoid chocolate, nuts, wheat products, oatmeal, soda, or other things containing high amounts of arginine. Also look into anti-viral medication if you can tolerate having the bottle visible in your medicine cabinet. It's such a stigmatizing thing for such a common a problem.
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  8. #8
    Registered User Zanderini's Avatar
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    why not just skip out on the arginine?
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  9. #9
    Registered User bmallen1's Avatar
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    Originally Posted by Zanderini View Post
    why not just skip out on the arginine?
    A lot of pre workout supplements contain it. As well as protein supplements. It's hard to avoid. But I'm currently looking into alternatives.
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  10. #10
    Registered User theproctologist's Avatar
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    never had this problem when I was taking bulk arginine
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  11. #11
    Registered User Zanderini's Avatar
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    Originally Posted by bmallen1 View Post
    A lot of pre workout supplements contain it. As well as protein supplements. It's hard to avoid. But I'm currently looking into alternatives.
    Protein only has arginine in the protein not added. Go with. Psu,vengeance,or others without arginine
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  12. #12
    Registered User bmallen1's Avatar
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    Originally Posted by theproctologist View Post
    never had this problem when I was taking bulk arginine
    Apparently I have an arginine sensitivity because I'm getting a cold sore 1-2 times per month. luckily they barely stick around a week with the way that i treat them but still getting them none the less.
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  13. #13
    Registered User theproctologist's Avatar
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    that's pretty weird, I've used it in bulk and in various PWOs and never experienced that. Do you know what causes that?
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  14. #14
    Registered User bmallen1's Avatar
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    Originally Posted by theproctologist View Post
    that's pretty weird, I've used it in bulk and in various PWOs and never experienced that. Do you know what causes that?
    No I don't know the cause exactly, I've just read numerous articles that say arginine promotes cold sore outbreaks and that lysine can help reduce and/or control outbreaks.

    I am working out pretty hard though, and putting my body through a lot of stress; maybe that has something to do with it.

    I'm going to try a different PWO though, maybe body forge or vengeance or who knows. I just know a PWO supplement can make or break my workout. It helps out considerably after a long day's work in the office.
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  15. #15
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    You have the herp.
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    If you workout in the morning, take your lysine with dinner. If you work out at night, take it with breakfast. Easy.
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  17. #17
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    Originally Posted by XMarineRunner View Post
    I have used Arginine in one form or another as a pre-workout supplement many times.... I love it.
    I too love the placebo-mediated effects from arginine-based supplements as well.
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  18. #18
    Mr Prawo Jazdy ElMariachi's Avatar
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    Arginine is basically useless as far as working out/building muscle goes. If you're prone to cold sores, there's really no way of taking in arginine and making yourself immune to cold sore appearance. You can try mega-dosing L-Lysine as some others have suggested but that is a crapshoot at best. There's plenty of preworkout products made without l-arginine that can help you get the pre-workout boost you're looking for and not subject you to a crazy looking growth on your face for like a week.
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