D aspartic acid (DAA) Test booster-the next big thing?

[musclephenom32]

Just read a 5 page article on DAA in the new Muscular development (March issue) saying this product was a great test booster yadda yadda. But at the end it says discountinue use at the first sign of Gyno?If its natural, why would it give you gyno?! And, are these products available yet? Is it a replacement for tribulus?

[Itadienekes]

Duh. This is why I hate the notion of "Natural" vs. "Non Natural" ... WTF does natural mean!? Is creatine natural? Is endogenous Test natural?

Anyway, if DAA really does drastically boost testosterone, then your body's estrogen levels will also rise and your manboobs might become prone to Gyno. It doesn't matter what is doing the testosterone boosting, whether it's a PH/DS/AAS or a 'natural' booster.

[homerunrbi]

Duh. This is why I hate the notion of "Natural" vs. "Non Natural" ... WTF does natural mean!? Is creatine natural? Is endogenous Test natural?

Anyway, if DAA really does drastically boost testosterone, then your body's estrogen levels will also rise and your manboobs might become prone to Gyno. It doesn't matter what is doing the testosterone boosting, whether it's a PH/DS/AAS or a 'natural' booster.

THISSSSSSSSSSSSS. With almost anything there is a positive and a negative. Think of it as if you jump you fall.

[sl4vik]

Already out by some Italian company, sold only in Europe.

[Mike83]

I read the article as well, it might be the next big thing.

[UNCnate]

Just read a 5 page article on DAA in the new Muscular development (March issue) saying this product was a great test booster yadda yadda. But at the end it says discountinue use at the first sign of Gyno?If its natural, why would it give you gyno?! And, are these products available yet? Is it a replacement for tribulus?

Anything that alters your hormonal balance can cause gyno. Doesnt matter if its from a natural source, or not.

[ElMariachi]

I'm honestly concerned about any potential negative interactions with these supplements. DAA shouldn't be too much of a concern but the fact that companies are putting in active doses of NMDA into supplements is disconcerting.


Even in small doses, studies have shown that NMDA can lead to migraine's and other related issues in those who are prone to them. I don't see the overall benefit of happily ingesting a neurotoxin just for some "gains, brah!"

[Achilles_1986]

Already out by some Italian company, sold only in Europe.

Anabolic Xtreme is using it as well. Check out their forum, its some sort of "booster" to their new Mass FX and Hyperdrol.

[Achilles_1986]

Almost 50% MORE Testosterone in Just Over 2 Weeks from the TST PowerCell alone?


The new Pro Series of Anabolic Xtreme products features an exclusive, limited edition "Power Upgrade Package" for users to supercharge their results. Knowing that naturally elevating testosterone is the absolute BEST and fastest way to build muscle, strength, power, and stamina, we wanted to offer users a means by which they could naturally produce even MORE testosterone for potentially faster, more immediate results. Our goal was told fold. 1) Keep it natural and non-steroidal, and 2) it must be incredibly potent. Needless to say, we had quite the challenge at hand, and we are always up for a good challenge!

So what did we come up with? Make sure you are sitting down.

Natural? Check.

Non-steroidal? Check.

Potent? You bet your @$$ it is!

The TST PowerCell is driven by an immense dose of D-Aspartic acid. D-Aspartic acid is a naturally occurring, endogenous amino acid that is found in nervous and endocrine tissues of the human body. It is suggested to play an important roll in the development of the nervous system, and may play a very important role in the quality of semen and sperm cell production.

So how does this apply to YOU, the iron crushing, have-no-limits, record setting athlete who is constantly redefining boundaries? While scientific research into this naturally occurring amino acid is relatively new, the limited human research suggests that D-aspartic acid may enhance luteinizing hormone and testosterone by 46% and 45.5% respectively, in only 13 days. That is a near 50% increase in your natural testosterone production in just over 2 WEEKS! In addition, animal studies indicate that D-Aspartic acid can naturally enhance levels of human growth hormone through the same mechanisms by which HGH is produced in humans.

So how does this naturally occurring amino acid work inside our bodies? Let's take a look!
Laying the Building Blocks for More Testosterone.

Evidence suggests that D-Aspartic acid increases cAMP in the testes, and cGMP in the pituitary. Both cAMP and cGMP act as secondary messengers. In the pituitary, cGMP influences luteinizing hormone production, and more cGMP is believed to lead to more LH. LH is important because it is the hormone that travels from the pituitary down to the leydig cells of the testes. Inside the leydig cells it signals testosterone production. Enter cAMP.

cAMP acts as a secondary messenger that increases StAR expression. StAR is a carrier protein that helps bring cholesterol, the building block of testosterone, into the testosterone manufacturing power plant of the leydig cells. Thus, more cAMP is believed to lead to more testosterone production, as is seen in the human trials performed on D-Aspartic acid.

D-Aspartic acid may also increase human growth hormone output. When using D-Aspartic acid, animal studies reveal high concentrations of endogenous NMDA (N-methyl-d-aspartic acid) in the brain. D-Aspartic acid is converted into NMDA which enhances the release of Growth Hormone Release Hormone (GHRH) and Gonadotropin-releasing hormone (GnRH), also known as luteinizing-hormone releasing hormone (LHRH). GHRH does exactly what is sounds like, releasing growth hormone into the body. However, while human trials specifically measuring for this outcome are needed, it is certainly an interesting possibility to consider and welcome effect if D-Aspartic acid does increase concentrations of human growth hormone. The benefits of human growth hormone are certainly very advantageous to athletes and bodybuilders.

If you hold the belief that you can never have too much power, then the Pro Series Power Packs, developed by Anabolic Xtreme, are for you.

[Robboe]

I'm honestly concerned about any potential negative interactions with these supplements. DAA shouldn't be too much of a concern but the fact that companies are putting in active doses of NMDA into supplements is disconcerting.


Even in small doses, studies have shown that NMDA can lead to migraine's and other related issues in those who are prone to them. I don't see the overall benefit of happily ingesting a neurotoxin just for some "gains, brah!"

Yeah i'm not sure i'd be willing to mess around with NMDA.

[Macrobolic]

Saw the same article, and the human study posted really gives this ingredient some potential. Upregulating HPTA, increasing endogenous test, good stuff.

[chasinSKURT]

Anyway, if DAA really does drastically boost testosterone, then your body's estrogen levels will also rise and your manboobs might become prone to Gyno. It doesn't matter what is doing the testosterone boosting, whether it's a PH/DS/AAS or a 'natural' booster.

Increases in natural T levels will antagonize estrogens. It's virtually impossible to experience any symptoms of gynecomastia from natty T boosters

PH/DS's don't boost testosterone either.

[Itadienekes]

Increases in natural T levels will antagonize estrogens. It's virtually impossible to experience any symptoms of gynecomastia from natty T boosters

PH/DS's don't boost testosterone either.

No, PH/DS's won't. But what about pure injectable Testosterone? Increase in natural T levels from a booster should have the same effect as XXmg/week of Testosterone injections, and I sure as hell know that any Test injection increases aromatization and therefore estrogen levels, therefore increasing risk of gyno. Do I have something completely wrong?

[chasinSKURT]

No, PH/DS's won't. But what about pure injectable Testosterone? Increase in natural T levels from a booster should have the same effect as XXmg/week of Testosterone injections, and I sure as hell know that any Test injection increases aromatization and therefore estrogen levels, therefore increasing risk of gyno. Do I have something completely wrong?

testosterone depots and natty test boosters really cannot even be compared.

[Itadienekes]

testosterone depots and natty test boosters really cannot even be compared.

Again, AGREED. I'm even of the strong opinion that natty test booster really don't do anything but placebo. In any case, isn't the mechanism the same? Increase in testosterone leads to increased aromatization leads to increased estrogen leads to increased risk of gyno. Independently of where the testosterone is coming from or how big the increase in test is...

Just trying to understand, don't wanna be an ass.

[chasinSKURT]

Again, AGREED. I'm even of the strong opinion that natty test booster really don't do anything but placebo. In any case, isn't the mechanism the same? Increase in testosterone leads to increased aromatization leads to increased estrogen leads to increased risk of gyno. Independently of where the testosterone is coming from or how big the increase in test is...

Just trying to understand, don't wanna be an ass.

The increase in test from a natty test booster isn't gonna cause gyno, our bawlz just can't produce THAT much. Where as injectables aren't dependent on natural production, so your T levels are unlimited.

[bloodsimple1234]

The increase in test from a natty test booster isn't gonna cause gyno, our bawlz just can't produce THAT much. .

speak for yourself!

[MWarfare]

Yeah i'm not sure i'd be willing to mess around with NMDA.

I'm honestly concerned about any potential negative interactions with these supplements. DAA shouldn't be too much of a concern but the fact that companies are putting in active doses of NMDA into supplements is disconcerting.


Even in small doses, studies have shown that NMDA can lead to migraine's and other related issues in those who are prone to them. I don't see the overall benefit of happily ingesting a neurotoxin just for some "gains, brah!"

Hi there... hope this clears up some confusion....

N-Methyl-D-Aspartate is 100X's as potent as D-Aspartic Acid in stimulating hGH and Testosterone increases and is actually "ultimately responsible" for the hormone increase with D-Asp ingestion. D-Asp breaks down into n-Methyl-D-Aspartate via methyl transferace reaction called NMDA Synthetase. N-Methyl-D-Aspartate then stimulates the Hypothalamus-Pituitary and testis to produce hormones. So, if you take D-Aspartic Acid, it is the N-Methyl-D-Aspartic Acid, which gets there through conversion, that actually does the work.

Like anything, dosing is an important consideration. You can drink too much caffeine, take too many vitamins, actually drink too much water and it would be toxic...

Our company has performed the research and studies... the base ingredient in the formula is D-Aspartic acid with very small amounts of N-Methyl-D-Aspartate, which is proprietary... Dose only has to be VERY SMALL to elicit a HUGE synergistic effect with the D-Asp.

Some studies show 1000%+ increase in hGH in some mammals in only 1-2 hrs with only very small dose of N-Methyl-D-Aspartate. LH and Testosterone increases are also very impressive, without side effects. These studies where wtih dosages in the 2.5mg/kg ... Ours is much, much lower... in the miligram to microgram range per serving, not per kilogram... but yet still highly effective.

Here is a link that explains a lot of the answers to your potential questions here, Plus elaborates on this science in much greater depth. Plus, like 30 abstracts for substantiation.

On the link, there's a research paper and two pilot studies. Check em out.

musclewarfare (dot) com /rnd

I haven't posted enough times here to put an actual link... but the page and articles for reference are on the Muscle Warfare Website, in the R&D section.

Thanks

MWarfare

Muscle Warfare

[ElMariachi]

Hi there... hope this clears up some confusion....

N-Methyl-D-Aspartate is 100X's as potent as D-Aspartic Acid in stimulating hGH and Testosterone increases and is actually "ultimately responsible" for the hormone increase with D-Asp ingestion. D-Asp breaks down into n-Methyl-D-Aspartate via methyl transferace reaction called NMDA Synthetase. N-Methyl-D-Aspartate then stimulates the Hypothalamus-Pituitary and testis to produce hormones. So, if you take D-Aspartic Acid, it is the N-Methyl-D-Aspartic Acid, which gets there through conversion, that actually does the work.

Like anything, dosing is an important consideration. You can drink too much caffeine, take too many vitamins, actually drink too much water and it would be toxic...

Our company has performed the research and studies... the base ingredient in the formula is D-Aspartic acid with very small amounts of N-Methyl-D-Aspartate, which is proprietary... Dose only has to be VERY SMALL to elicit a HUGE synergistic effect with the D-Asp.

Please cite the studies and the research that your company has performed?



Edit-N/M..........if this is what passes for real studies with you guys, I think I know all I need to.

http://musclewarfare.com/rnd_s002.html
http://musclewarfare.com/rnd_s001.html

Some studies show 1000%+ increase in hGH in some mammals in only 1-2 hrs with only very small dose of N-Methyl-D-Aspartate. LH and Testosterone increases are also very impressive, without side effects. These studies where wtih dosages in the 2.5mg/kg ... Ours is much, much lower... in the miligram to microgram range per serving, not per kilogram... but yet still highly effective.

Yet there are no long-term studies of NMDA safety, not to mention that high NMDA intake has been linked with Alzheimer's and other such conditions. Too much of anything is never a good thing but when you have something that is a neurotoxin in the first place, why bother risking it?

[MWarfare]

Not to sound like I am scolding you ... because I'm not... but...

Why take vitamins at all if when you take too much it will be toxic?

Why drink water if when you drink too much it will be toxic?

Just like the prior two exapmles I just gave you... N-methyl-D-Aspartate "IS PRESENT IN YOUR BODY RIGHT NOW".... So calling it a neurotoxin is innaccurate... in high doses... similar to the amino acid Glutamate, it is considered excitotoxic... but, this typically occurs when they diasect Rats brains and administer it directly to brain tissue to test disruption of the ION channel in the liked name receptor. I'm sure that adding some vitamins and even pure water to the brains of mice in the same manner would be determined dangerous to brain and spinal nerves no? So, the correlation is not accurate.

Also... because your brain contains N-Methyl-D-Aspartate in it RIGHT NOW.... I wouldnt consider your brain toxic right?

So just to clarify, supplementing the correct dose fo D-Asparitic Acid and N-Methyl-D-Aspartic Acid can help promote a mild stimulation of this receptor to produce hormone spikes. The levels of these aminos typically rise with puberty and other times of hormonal change and body development anyway. So, the right amoiunt of supplementation is a natural process. Additionally, ALL of our beta testers loved the product with NO SIDE EFFECTS. Furthermore... the two pilot studies we point to above clearly show the dosing is much lower than one might think. Additionally, it was still highly effective.

As far as siting the studies... I told you I have not posted here enough to list links in my posts... so please decipher the web url below for reference...

So, here is the other article on that page, which you failed to list that clearly talks about effective dosing and toxicity research and other points you make here....

There are over 30 published studies connected to this article... please read the entire report...

www (dot) musclewarfare (dot) com / rnd_nmda (dot) html

Please cite the studies and the research that your company has performed?



Edit-N/M..........if this is what passes for real studies with you guys, I think I know all I need to.

[









Yet there are no long-term studies of NMDA safety, not to mention that high NMDA intake has been linked with Alzheimer's and other such conditions. Too much of anything is never a good thing but when you have something that is a neurotoxin in the first place, why bother risking it?

[Patrick Arnold]

I have a US patent application for the use of d-aspartic acid to increase testosterone in humans. NMDA is included in there too. This application has been pending well before any of the latest research and well before the italian formula was out. Any companies should be aware of this, and the potential financial penalties for patent infringement

[iForce Dave]

I have a US patent application for the use of d-aspartic acid to increase testosterone in humans. NMDA is included in there too. This application has been pending well before any of the latest research and well before the italian formula was out. Any companies should be aware of this, and the potential financial penalties for patent infringement

mind - blown

[DR_P]

Not to sound like I am scolding you ... because I'm not... but...

Why take vitamins at all if when you take too much it will be toxic?

Why drink water if when you drink too much it will be toxic?

Just like the prior two exapmles I just gave you... N-methyl-D-Aspartate "IS PRESENT IN YOUR BODY RIGHT NOW".... So calling it a neurotoxin is innaccurate... in high doses... similar to the amino acid Glutamate, it is considered excitotoxic... but, this typically occurs when they diasect Rats brains and administer it directly to brain tissue to test disruption of the ION channel in the liked name receptor.

what you say is correct, but it lacks some necessary information in order to be useful:

1. by how much are regional extracellular brain levels of NMDA increased after a single dose of x mg of d-aspartic acid?

2. by how much is neuronal calcium influx increased after x mg of oral d-aspartic acid?

3. by how much is neuronal calcium influx increased after x mg of oral d-aspartic acid under conditions of fluctuating brain blood circulation (such as during training)?

4. levels of neuronal ROS markers after x mg of d-aspartic acid?

5. levels of apoptosis markers after x mg of d-aspartic acid?


I am sure that you agree that answers to these questions are of relevance when discussing the potential safety of oral exogenous administration of d-aspartic acid (let alone oral NMDA).

[Sldge]

Yeah i'm not sure i'd be willing to mess around with NMDA.

I have a US patent application for the use of d-aspartic acid to increase testosterone in humans. NMDA is included in there too. This application has been pending well before any of the latest research and well before the italian formula was out. Any companies should be aware of this, and the potential financial penalties for patent infringement

Arent their studies showing its effects on testosterone in rodents and monkey's going back to the early 90's?

[liftNfish]

In after PA

[musclephenom32]

I have a US patent application for the use of d-aspartic acid to increase testosterone in humans. NMDA is included in there too. This application has been pending well before any of the latest research and well before the italian formula was out. Any companies should be aware of this, and the potential financial penalties for patent infringement

Wow, you're on top of your game!
.

[musclephenom32]

Anabolic xtreme is coming out with a new product pro series power packs with DAA in it, looks very promising.
It's on their forums tstpowercell/along with mssfx the destroyer, a mass fx powerpack. Looking forward to trying it since I got good results from the original mass fx. I hope bb is going to carry it/ they said its already shipping to retailers. I'm picking up a couple boxes (:}

[UHCougar05]

I have a US patent application for the use of d-aspartic acid to increase testosterone in humans. NMDA is included in there too. This application has been pending well before any of the latest research and well before the italian formula was out. Any companies should be aware of this, and the potential financial penalties for patent infringement

Things are about to get spicy...

[Macrobolic]

I have a US patent application for the use of d-aspartic acid to increase testosterone in humans. NMDA is included in there too. This application has been pending well before any of the latest research and well before the italian formula was out. Any companies should be aware of this, and the potential financial penalties for patent infringement

[user1111]

Just read a 5 page article on DAA in the new Muscular development (March issue) saying this product was a great test booster yadda yadda. But at the end it says discountinue use at the first sign of Gyno?If its natural, why would it give you gyno?! And, are these products available yet? Is it a replacement for tribulus?

It also increases prolactin significantly....