I'm studying for my Personal Training certificate, and I see this goddamn term used over and over again
what does it mean? I keep seeing terms like puryvate (sp?) = energy substrate deemed as end product of glycosis
I googled it and none of the answers made any sense
12-28-2009, 10:32 PM #1
What the hell does the word Substrate (ie energy substrate) Mean ?
12-28-2009, 10:34 PM #2
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12-28-2009, 10:47 PM #3
12-28-2009, 11:08 PM #4
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Pyruvate is a by-product of the gycolysis process, where one molecule of glucose produces 2 ATP. If you look at the definitions of pyruvate, you'll find it's the simplest alpha-keto acid. Cells can actually metabolize pyruvate (or use as energy) following a chemical enzymatic reaction. Excess pyruvate becomes lactic acid.
One definition of "substrate" I've found in biochemistry is: "a molecule upon which an enzyme acts. Enzymes catalyze chemical reactions involving the substrate(s). In the case of a single substrate, the substrate binds with the enzyme active site, and an enzyme-substrate complex is formed."
So basically, what your material is saying is that the simple acid, pyruvate, is a molecule on which an enzyme acts as a catalyst in the production of energy. At least that's what I think is being said and someone can correct me if I'm wrong. I've been going through the whole bionergetic continuum stuff myself just today.
Last edited by torn8o; 12-28-2009 at 11:11 PM.NASM CPT
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12-29-2009, 01:25 AM #5
Macronutrients are the three calorie containing nutrients (fats, proteins, and carbohydrates).
They are also the energy substrates that can be broken down in our cells to release their stored energy. Each of our cells contain chemical pathways that convert these substrates to energy that can be used by that cell and other cells of the body.
Glycolysis produces pyruvate (aka pyruvic acid). The fate of pyruvate will be determined by the rate of ATP utilization and the presence of oxygen. In fast glycolysis, pyruvate will be converted to lactic acid then to lactate which can then leave the cell. In slow glycolysis, pyruvate will be converted to acetyl CoA and enter the Krebs Cycle. You produce more ATP per glucose with slow glycolysis but the rate of ATP production is much slower.
12-29-2009, 11:05 AM #6
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12-29-2009, 11:34 AM #7
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12-29-2009, 12:00 PM #8
So happy I passed Organic Chem and Bio Chem. Never to go back, phew.http://sagefit.wordpress.com/
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