Big thanks to Steve from Cognitive Nutrition for sponsoring this log with Mito Charger from Advanced Orthomolecular Research. I also purchased some Cognitive Nutrition PEA 750mg to give some brief feedback on.
I also use numerous other AOR products including Ortho Core as my multi source, Ortho Mind for cognitive health, Advanced Whey, Greens n' Berries, Ortho Glucose II, Ortho Liver II, Advanced Biotics, Vitamin D3 Liquid and more... AOR has done a tremendous job on many of their newest formulations in the past year or two. As much as I have liked them in the past, they continue to strive to new heights.
This might be a hard product to 'Feel' or notice within weeks, but done right, long term I do believe these nutrients can assist in preventing disease and enhancing performance by improving the health of the cell. You should feel and notice a difference with time as improved mito functioning works its powers. I think anyone can appreciate the ingredients and dosings provided here and see the quality product for what it is. I would quickly take this product over 90% of anything out there if I were to pick from all the products to use in the supplement world. I hope to take 3-6 caps early on most days over the next month in this log, but this is def. a staple as I purchased another 6 bottles for myself and family. My dad and mom are in their 70's and doing just fine with my advice so far.
This log will likely be as much about providing info as it is simply providing workout/training feeback to any of the interested bb.com members. I hope to begin using my indoor bike training for cardio as I have a new love for endurance competition which will compete with my love for bodybuilding/strength training. I was hoping to do a very short bulk/strength gain in the next two months, but because I can't wait to begin using a bike trainer now, it may be very limited this year. Oh well, at least I will be healthy and get in great shape and stay fairly lean.
MITO CHARGER from AOR:
Serving Size: 6 Capsules
R(+)- Lipoic Acid 150 mg
Co-Enzyme Q10 100 mg
Rhodiola Rosea (min. 3% rosavins, 1% salidroside) 150 mg
Benfotiamine 150 mg
Oxaloacetic acid (Benagene) 100 mg
D-Uridine 50 mg
Gynostemma Pentaphyllum Extract 100 mg
Acetyl-L-Carnitine (ALCAR) 1500 mg
This is one of the products I have had on my most wanted list for close to a year now. If you learn more about disease, aging and performance enhancement, you'll soon discover that there is no way either can be addressed optimally without first providing healthy mitochondria.
Here is a little starting info From Wiki:
Mitochondria are sometimes described as "cellular power plants" because they generate most of the cell's supply of adenosine triphosphate (ATP), used as a source of the chemical energy. In addition to supplying cellular energy, mitochondria are involved in a range of other processes, such as signaling, cellular differentiation, cell death, as well as the control of the cell cycle and cell growth. Mitochondria have been implicated in several human diseases, including mitochondrial disorders and cardiac dysfunction, and may play a role in the aging process.
Here is AOR's writeup for their product ProChondria which is exactly the same as Mito Charger except Mito has ALCAR instead of the carnitine precursor GBB. ALCAR is preferable imo.
Maintains mitochondrial health
+ Mitochondrial Dysfunction
+ Enhances mitochondrial activity on six different levels
+ Ultimate Free Radical quencher
+ Important for virtually all diseases
The Importance of the Mitochondria
The cell is the basis of all life, and the mitochondrion is the power plant that keeps the cell
operating. A simple but effective metaphor for what is one of the most significant and complex biochemical relationships known to science. Without mitochondria, cells simply do not produce the energy needed for the human body to function or even survive. It comes as little surprise, that any state of mitochondrial dysfunction can be associated with a host of metabolic conditions, including metabolic syndrome, aging, obesity, kidney, liver and neurological diseases.
Mitochondria and ATP
Mitochondria are bacteria-sized organelles, and thousands are located inside the membrane of each cell. The primary function of the mitochondria is to convert organic materials (originating mainly from the food we eat) into energy in the form of ATP (adenosine triphosphate - the immediate fuel of life). The rate at which the mitochondria perform this function is called the Basal Metabolic Rate (BMR), and an increased BMR leads to increased insulin sensitivity, which in turn leads to the greatest safeguard against a host of metabolic disorders, including the increasingly present Metabolic Syndrome.
The Vicious Cycle
Ironically, the mitochondria's ability to produce ATP also results in the simultaneous production of other, unproductive metabolic by-products, particularly ROS (reactive oxygen species) free radicals.
The Mitochondrial Theory of Aging
The aforementioned 'vicious cycle' has become known as the Mitochondrial Theory of Aging. An inefficient mitochondrion generates more free radicals than an efficient one. This is because, as we age, more fuel (in the form of glucose, amino acids and fatty acids) is required for each mitochondrion to produce the same amount of ATP, resulting in an increased ratio of ROS-to-ATP production. To complicate matters further, mitochondrial DNA (mtDNA) differs from the DNA of the nucleus and other organelles in that mtDNA has no enzymatic defense against oxidative stressors, self-generated or not. In-vivo studies have provided evidence for the Mitochondrial Theory of Aging so conclusive that one leading researcher summarized it this way: "It is generally accepted that oxidative mitochondrial decay is a major contributor to aging."
Maintaining The Power Plant - With Cocktails
As we have seen, the relative clarity of the mitochondria's role within human biochemistry is coupled with an inherent vulnerability that must be addressed if any attempt is to be made with regard to enhancing mitochondrial health. The process of addressing the elusive prerequisites to mitochondrial health is so intricate that professional medical societies have been established exclusively for its study. These include the Mitochondrial Research Society (Buffalo, N.Y.), the Mitochondrial Physiology Network (Innsbruck, Austria), and the United Mitochondrial Disease Foundation (Pittsburgh, PA), among others. Their efforts have helped to create a plethora of complex nutraceutical formulations designed to enhance mitochondrial function and health from every conceivable perspective.
I also hope to post more on the Mitochondrial Theory of aging, Mitochondria Diseases and the interesting nutrient research done by the likes of Dr. Bruce Ames and others.
For a more in-depth reading from AOR on Mitochondria and anti-aging, check out their Advances Magazine Vol3 Issue3: