GTE (Green Tomato Extract)

BULLandTERRIER · 09-22-2009, 02:08 PM

In order to determine the effects of [GTE] compound administration on muscle growth and strength in human, the following study was conducted.

SUBJECTS AND METHODS
28 healthy adult males ages 30-55 who were enrolled in a weight-training program to build muscle mass were invited to participate in a study. All subjects were nonsmokers, on no medications, and in good health. Each subject had been enrolled in a weight-training program for at least one year. 14 subjects received the active compound and 14 subjects received a placebo pill identical in appearance. Both groups of subjects took one pill a day by mouth for six weeks. Weight training consisted of a three times per week exercise routine for six weeks.

MEASUREMENTS

A number of anatomic and functional measurements were obtained on each subject prior to starting and at the completion of the study. These measurements included height (as measured with a calibrated Health O Meter statiometer), weight (on a balance beam scale wearing light clothes and no shoes), body mass index (body mass index = weight (kg)/height (m)2), waist circumference (measured at the level of the umbilicus), biceps measurement (the circumference of the dominant biceps muscle measured at the middle of the muscle belly of the flexed muscle quadriceps measurement (circumference of the dominant thigh measured 4" above the kneecap while the subject is standing in a relaxed posture) body composition, and skin fold measurement. (31,32,33,34) All measurements were performed in duplicate. Upper body strength was measured by asking each subject to do 10 repetitions on a bench press or an incline barbell at the maximum possible weight at which they are able to complete the 10 reps. Lower body strength was measured by asking the subject to perform 10 repetitions a the maximum possible weight on a leg press or leg extensions machine. Both baseline and final pressed weights were recorded for upper and lower body strength. Compliance was determined by subtracting the number of capsules returned by the subject at the final visit from the number of capsules dispensed at the outset of the study.

RESULTS

After six weeks, the subjects who took the Endothil core compound had a significant (p<0.05) increase in both upper and lower body strength as well as in circumference of the biceps muscle. Specifically, the amount of weight bench pressed increased by 10 lbs. in subjects receiving the active compound compared to an increase of 5 lbs. in subjects receiving placebo. The amount of weight leg pressed increased 70 lbs. versus 20 lbs. in placebo treated subjects. The biceps circumference increased by 0.45 cm (1 inch) while subjects receiving placebo showed no increase in biceps circumference. There were no significant changes between the two groups in quadriceps circumference, % body fat, % lean body mass, weight, or body mass index.

SUMMARY

These findings confirm the hypothesis that the active compound in Endothil, in conjunction with exercise, produces a significantly greater increase in both upper and lower body strength and in biceps circumference than exercise alone. Based upon the observations from laboratory experiments, for the compound to have maximum effect it needs to be incorporated into an exercise routine. The exercise routine will have the most effect if it results in muscle metabolic changes that will provide a stimulus for new blood vessel growth. By augmenting exercise-induced new blood vessel growth, the active compound in Endothil synergizes with the metabolic effects of exercise to increase muscle size and strength.