Sign in this thread if you want bb.com to start carrying this product. Great product for on it's own for overall health, but would also stack very well with pretty much any of the popular fat burners talked about on here. Hopefully this thread gets some attention and the CSR's at bb.com catch on!
Check it out:
R(+)-Lipoic Acid 150 mg
Co-Enzyme Q10 100 mg
Rhodiola Rosea (min 3% rosavins, 1% salidroside) 150 mg
Benfotiamine 150 mg
Oxaloacetic acid (Benagene ?)100 mg
D-Uridine 50 mg
Gymnostemma Pentaphyllum Extract 100 mg
Acetyl-L-Carnitine 1500 mg
Sign!The Mitochondrial Theory of Aging
Mitochondria generate damaging free radicals, and inefficient mitochondria generate even more free radicals than efficient ones. This is because more fuel is required by each mitochondrion to produce the same amount of ATP, resulting in an increased ratio of free radicals-to-ATP production. To complicate matters further, mitochondrial DNA (mtDNA) differs from regular DNA in that mtDNA has no enzymatic defense against oxidative stressors. In-vivo studies have provided evidence for the Mitochondrial Theory of Aging so conclusive that one leading researcher summarized it this way: "It is generally accepted that oxidative mitochondrial decay is a major contributor to aging."
Maintaining the Power Plant - With Cocktails
As we have seen, the relative clarity of the mitochondria's role within human biochemistry is coupled with an inherent vulnerability that must be addressed if any attempt is to be made with regard to enhancing mitochondrial health. The efforts of researchers around the world have helped to create a plethora of complex nutraceutical formulations designed to enhance mitochondrial function and health from every conceivable perspective.
How It All Works
Enzyme Bypass: The theory here is to circumvent defects in the process of ATP production. ATP production involves a lipid-soluble carrier called ubiquinone. The supplemental form of ubiquinone is Co-Enzyme Q10 (Co-Q10), and studies have shown that it can expedite certain phases of ATP production by up to 200%.
NAD+ is another key coenzyme that is converted into its reduced form, NADH, during ATP production. An increased ratio of NAD+/NADH helps improve ATP production, and has also been linked to the activation of genes that have been associated with anti-aging effects. Oxaloacetic acid (benaGeneTM) has been shown to increase the ratio of NAD+/NADH. It also mimics the effects of a calorie-restricted diet, which has been shown to increase life-span in several mammal species.
Antioxidants: Conventional anti-oxidants such as vitamins C and E are certainly useful, but the ideal mitochondrial antioxidant appears to be R(+)-lipoic acid. Lipoic acid is metabolized to its active form, diHydrolipoic acid (DHLA) inside the mitochondrion itself. This process produces intense biological activity, including the regeneration and recycling of vitamins C and E and enhanced insulin sensitivity.
Alternative Energy: This tactic involves the maximal utilization of a source of ATP that does not require any mitochondrial participation, thus augmenting overall ATP production without burdening dysfunctional or aging mitochondria. The herb Rhodiola rosea has demonstrated a capacity to increase ATP production.
Reducing Lactate: Lactate is a by-product of anaerobic energy production that can build up in the muscles and cause muscle cramping. Lactate is formed from pyruvate, and if pyruvate can be directed into the mitochondria, and away from lactate production, it can instead be used for further energy production. This can be accomplished with vitamin B1 supplementation. This has been made even more appealing by the development of benfotiamine, which is nearly 5 times more bio-available than conventional thiamin.
Nucleotide Precursors: Nucleotides are the structural units of DNA and RNA - including mtDNA and mtRNA. As mitochondrial dysfunction is closely associated with the depletion of nucleotides, maintaining a healthy nucleotide pool is paramount. Uridine seems to be able to do this, and naturally-derived uridine supplements have been studied for their ability to improve mitochondrial function in patients with HIV.
Vasodilation: Vasodilation (the widening of the blood vessels) is linked to the mitochondria via the production of nitric oxide. The mitochondria are primary targets of nitric oxide, and even small amounts can regulate ATP synthesis. Gynostemma pentaphyllum is a powerful nitric oxide enhancer.
Fatty Acid Utilization: Acetyl-L-carnitine (ALCAR) is a source of L-carnitine, a key molecule involved in cellular energy production and that is essential for proper mitochondrial function. The most important function of L-carnitine is to help shuttle fatty acids into the mitochondria, where they are then used as fuel for energy production. Depleted L-carnitine levels have been associated with muscle and heart dysfunction.
AOR's Mitocharger provides an advanced and effective formula to help support the mitochondria and to counteract aging associated with mitochondrial deficiencies.
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Thread: Petition for Mito Charger by AOR
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09-06-2009, 07:47 PM #1
- Join Date: May 2007
- Location: Rochester, New York, United States
- Age: 37
- Posts: 8,410
- Rep Power: 18850
Petition for Mito Charger by AOR
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09-06-2009, 07:50 PM #2
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09-06-2009, 08:11 PM #3
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09-06-2009, 08:12 PM #4
In!
While we are at it lets add Curcumin 95, Pomegranate Ultra, hell just add the whole line . I talked with one of the reps a few weeks ago about adding more stuff but never heard anything back.http://forum.bodybuilding.com/showthread.php?p=128438981#post128438981
Re-comp/AEN log.
http://forum.bodybuilding.com/showthread.php?t=106579071
UNC's 3AD log!!
S.A.N. Fierce Log!!
http://forum.bodybuilding.com/showthread.php?p=394225001#post394225001
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09-07-2009, 07:48 AM #5
Thanks Chasin', great idea and fellow AOR fan here!
I noticed this a few months back on a site in the US, but being in Canada we can't get this because of the ALCAR... there is the new AOR pro line only available through health professionals and they have a very similar product ProChondria:
http://www.aorpro.ca/html/products.php?id=171
R(+)- Lipoic Acid 150mg
Co-Enzyme Q10 100mg
Rhodiola Rosea (min. 3% rosavins, 1% salidroside) 150mg
Benfotiamine 150mg
Oxaloacetic acid (BenageneTM) 100mg
D-Uridine 50mg Microbial Synthesis
Gynostemma Pentaphyllum Extract 100mg
Gamma butyrobetaine (GBB) 1500mg
Notice the Gamma butyrobetaine (GBB) in place or ALCAR as this is available in Canada and is used as a precursor for carnitine. I get everything in those products from various other products including a few AOR products, except for D-Uridine and Gynostemma Pentaphyllum Extract. So for companies not using carnitines in their Canadian versions, there is no reason really or just need to know about GBB. Don't feel bad though
I have read quite a bit on these ingredients and AOR definitely has done there research in formulating Mito Charger. They definitely don't just look at what other companies are doing and copy the ingredients and doses and call it their own. That's the thing, they understand the ingredients, the research and how it works.
It could very well be one of the best products one could look to buy for overall health, disease prevention and even mental and physical performance. The mitochondria is where it's at!! ie. health mito = healthy person.
This is pretty cool and could help some looking into this further: Associated weaknesses within mito and startegies to address them.
Strategy Theoretical Basis Example
1. Enzyme Bypass Provide energy beyond the site of
the enzyme defect: Succinate, Co-Enzyme Q10.
2. Anti-oxidants Reduce free radical damage to
cell structures: Vitamin E, C, Lipoic acid.
3. Alternative energy Use an anaerobic system not requiring mitochondria: Creatine Monohydrate exogenous ATP.
4. Reduce lactate Reduce acidosis, more energy into the mitochondria: Dichloroacetate, thiamine.
5. Strength exercise Improve strength, reduce number
of mutant mtDNA: Weights, isometrics.
6. Endurance exercise Improve endurance, reduce
cardiovascular risks: Jogging, cycling, walking.
7.Nucleotide precursors Prevent depletion of nucleotide
pool (for DNA synthesis): Triacetyluridine, d-ribose, d-uridine
8. Vasodilation Prevent vascular spasm in
MELAS stroke: L-arginine, gynostemma entaphyllum
Anyways, for those interested you can read much more here: http://www.aorpro.ca/html/products.php?id=171
AOR has lots of hidden gems that the world of bb.com has been invisible to for much too long. I'm optimistic informed members such as those in this thread can appreciate the AOR difference with innovative, non-prop. and efficacious formulas such as Mito Charger, Ortho Core, R+SR, Curecumin and much more. I just hope some less welll-intentioned companies here don't insult these products with their own copied and cheapened versions.
I somehow I can get my hands on some Mito Charger I'll be a very happy man.
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09-07-2009, 08:00 AM #6
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09-07-2009, 08:21 AM #7
- Join Date: Jun 2009
- Location: North Carolina, United States
- Posts: 32,237
- Rep Power: 302249
well R(+)-Lipoic Acid is a very powerful antioxidant
and Co-enzyme Q10 regulates the flow of oxygen in and out of the mitochondria the cells power plants.
Since i have high blood pressure i have been taking COQ-10 for years to protect my heart.
Those two ingredients alone is why i would love to see it on bb.com...i don't buy from anywhere elseKrispy Kreme Krew Forever.
Disclaimer: The above post is my personal opinion and does not represent the official position of any company or entity.
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09-07-2009, 08:24 AM #8
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09-07-2009, 08:46 AM #9
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09-07-2009, 08:48 AM #10
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09-07-2009, 12:44 PM #11
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09-07-2009, 04:32 PM #12
There are better (at least in terms of bioavailbility) forms of each though. However, it may contribute to a higher production cost though the lower dosing needed would offset to some manner. I'm a bit surprised at the number of ingredients sourced from China. While nothing inherently wrong with it, I thought they may have sourced from more reputable manufacturers like Geronova.
Benagene always interested me but with other alternatives to affect NAD+ levels and its relative expensive dissuaded me a bit--not to mention the malic acid proposals. I do wonder if they ever completed the trials on rats and the effect it had on lifespan.Yes, there is indeed a deeper component to it all.
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09-07-2009, 04:40 PM #13
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09-07-2009, 04:42 PM #14
They have no qualms hiding the fact that they (like every other company) source ingredients from China... obvious when they point this out on their own site!! I have also read their thoughts and discussions on such matters... they go out of their way to be forthright and honest. There are good, reputable sources from China, just as there are bad... AOR is known for their high standards and independently test their ingredients. If you can't trust AOR, you can't trust any company.
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09-07-2009, 04:43 PM #15
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09-08-2009, 05:39 PM #16
I did what I could, I just emailed Jeremy about it getting this and other AOR products.
http://forum.bodybuilding.com/showthread.php?p=128438981#post128438981
Re-comp/AEN log.
http://forum.bodybuilding.com/showthread.php?t=106579071
UNC's 3AD log!!
S.A.N. Fierce Log!!
http://forum.bodybuilding.com/showthread.php?p=394225001#post394225001
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09-08-2009, 05:49 PM #17
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09-08-2009, 05:57 PM #18
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09-08-2009, 06:18 PM #19
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09-08-2009, 06:35 PM #20
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09-08-2009, 06:37 PM #21
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09-08-2009, 06:38 PM #22
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09-08-2009, 06:39 PM #23
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09-08-2009, 06:50 PM #24
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09-08-2009, 06:51 PM #25
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09-08-2009, 09:19 PM #26
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09-08-2009, 09:30 PM #27
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09-08-2009, 09:30 PM #28
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09-08-2009, 09:34 PM #29
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09-08-2009, 10:01 PM #30
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