What is 2-phenyl-di-benzyl-benzopyran-4-one? Is this the same thing as Androsterone? This is the main ingredient in my new bottle of LG T-911 that has a sticker saying "Updated Formula". bb.com says Androsterone is the main ingredient.
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06-14-2009, 04:55 PM #1
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06-29-2009, 08:01 PM #2
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06-29-2009, 09:58 PM #3
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This is the naming of some complex chemical, maybe using the Abstract Chemical Service, but definitely not using IUPAC. Whoever wrote this on the label is absolutely misleading and I won't trust this chemist. Maybe it's androsterone, but it would take someone with at least a BSc majoring (Honours) in chemistry to draw this and compare it to the known structure of androsterone.
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08-16-2009, 08:10 AM #4
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08-16-2009, 08:31 AM #5
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08-17-2009, 05:16 PM #6
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08-17-2009, 05:54 PM #7
It looks like a misprint, if you check LG Sciences website;
T-911 contains:
2-Phenyl-benzo(h)chromen-4-one
I don't have any advanced chemisty knowledge to help out any further, but it's a start.Ball-Worthy [bawl-wur-thee]
-adjective
1) Something so epic you would sacrifice a testicle to get your hands on it:
-nano's journal is ball-worthy;
http://forum.bodybuilding.com/showthread.php?t=117646471
-nano's guitar
http://forum.bodybuilding.com/showthread.php?t=124088321
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08-18-2009, 01:42 PM #8
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01-22-2010, 05:39 PM #9
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01-22-2010, 07:45 PM #10
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01-25-2010, 07:15 AM #11
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It is a 7,8-benz derivative.
On paper, it's about 10x stronger than the AI in our original formula. Some don't report the same psychological effects as the first version, but strength gains and performance seem to be on par if not better.Self-proclaimed Constitutional Conservative-Libertarian Hippie.
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01-25-2010, 07:54 AM #12
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01-25-2010, 12:53 PM #13
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01-25-2010, 12:54 PM #14
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01-25-2010, 12:56 PM #15
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01-26-2010, 07:05 AM #16
Not sure about human pharmacokinetic data on alpha-NF however, [Wang X, Morris ME. J Pharm Sci. 2008] indicated a rather low bioavailability in rodents and that pharmacological practicality for breast cancer resistance protein treatment was entirely dose-dependent.
~
Wherever progression lacks.... regress can be found in abundance.
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01-26-2010, 07:48 AM #17
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01-26-2010, 08:03 AM #18
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02-03-2010, 09:22 PM #19
Pharmacokinetics and bioavailability of the flavonoid 7,8-benzoflavone in rats
Xiaodong Wang, Marilyn E. Morris *
Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, 517 Hochstetter Hall, Amherst, New York 14260
email: Marilyn E. Morris (memorris@buffalo.edu)
*Correspondence to Marilyn E. Morris, Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, 517 Hochstetter Hall, Amherst, New York 14260. Telephone: 1-716-645-2842 ext 230; Fax: 1-716-645-3693.
Keywords
7,8-benzoflavone • BCRP • bioavailability • oral absorption • pharmacokinetics • ADME • drug interaction
Abstract
The flavonoid 7,8-benzoflavone was recently identified as one of the most potent inhibitors of breast cancer resistance protein (BCRP); however, little is known of the in vivo disposition of 7,8-benzoflavone. The objective of this study was to investigate the pharmacokinetics and bioavailability of 7,8-benzoflavone in rats. Three intravenous (5, 10, and 25 mg/kg) and three oral (12.5, 25, and 50 mg/kg) doses were administered to female Sprague-Dawley rats. Plasma samples were analyzed by high-performance liquid chromatography. Pharmacokinetic analysis was conducted by WinNonlin and ADAPT II. The dose-normalized plasma concentration versus time curves did not superimpose with each other, indicating the nonlinear pharmacokinetics of 7,8-benzoflavone. 7,8-benzoflavone exhibited a large volume of distribution (Vss 1.5 L/kg) and rapid oral absorption (tmax < 30 min). The bioavailability of 7,8-benzoflavone was low (0.61-13.2%) and dose-dependent. A pharmacokinetic model with dose-dependent bioavailability, linear absorption and nonlinear elimination best described the pharmacokinetic profiles of 7,8-benzoflavone. Using a 50 mg/kg oral dose of 7,8-benzoflavone, we could significantly increase the AUC for the BCRP substrate nitrofurantoin, demonstrating the potential for BCRP-mediated drug interactions. ? 2008 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 97:4546-4556, 2008Last edited by warugaki; 02-04-2010 at 12:21 PM.
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02-26-2010, 10:58 PM #20
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03-16-2010, 04:09 PM #21
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bump - Im not a science nerd - what does the descriptions above mean??
does it mean since its not bio-available its not going to work well? LG science guys any help here?
any information on this product would be helpful...
is it only for PCT ?
can you just use it as is?
do you have to cycle it?
thanks
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03-16-2010, 05:29 PM #22
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03-17-2010, 12:07 AM #23
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