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  1. #1
    Registered User Faktum's Avatar
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    Forskolin for tanning?

    I've heard that Foroskolin might help with tanning, any experiences with that?
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    Registered User Babylon1023's Avatar
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    Now that sure would be interesting to know. Bumpage.
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    Originally Posted by Faktum View Post
    I've heard that Foroskolin might help with tanning, any experiences with that?
    only topical. but then you need a topical formulation, which certainly won't be that easy.
    ThermoLife scientific consultant
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  4. #4
    Registered User Faktum's Avatar
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    It's pretty new, but if you combine it with Reservatrol it's supposed it might work though..
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    Registered User jsVR-4's Avatar
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    Give it a shot and let us know.

    I remember reading tyrosine helped.
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    Banned Adrenolin's Avatar
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    Originally Posted by Faktum View Post
    It's pretty new, but if you combine it with Reservatrol it's supposed it might work though..
    but you would still need dmso or Penetrate (believe that is the name..) to get it absorbed topically
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  7. #7
    Banned Adrenolin's Avatar
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    Originally Posted by jsVR-4 View Post
    Give it a shot and let us know.

    I remember reading tyrosine helped.
    yes it does, tyrosine and copper applied topically will accelerate tanning.
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  8. #8
    Registered User Faktum's Avatar
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    What is topically lol? Copper is good for tanning by the way, same with betacaroten..
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  9. #9
    Evolutionary Muse dsade's Avatar
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    Originally Posted by ADREN0LIN View Post
    yes it does, tyrosine and copper applied topically will accelerate tanning.
    tyrosine converts to l-dopa, which then converts to melanin.

    Skip the middleman and just use Atomic Meltdown, which contains both.
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  10. #10
    _/\/\/\/\/\/~>>> ToshiroMifune's Avatar
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    In order ot metabolize into melanin, tyrosine needs to interact with:

    B9
    B3
    C
    S-AM
    cuprum

    ************************************************** ********
    By Rachael Myers Lowe, cancerpage.com

    (September 21, 2006) - Researchers in Boston have developed a cream that causes the skin to tan. So far, it?s only been tested on mice and Dr. David E. Fisher of the Dana Farber Cancer Institute cautions that tests on humans are still a couple of years away.

    The research is published in the September 21 issue of the journal Nature.

    "The goal of the study," Dr. Fisher told cancerpage.com, " was to understand mechanistically how ultraviolet (UV) radiation induces skin darkening, what we know as the tanning process."



    "We stumbled across a surprising discovery," he said.

    The UV radiation didn?t appear to be acting directly on the pigment cells - the melanocytes ? that darken the skin but rather acted indirectly by stimulating the production of a hormone that attaches to the pigment cells and begins a series of chemical changes that lead to skin tanning. In the fair-skinned mice this hormone couldn?t attach and the chemical chain-reaction was stopped in its tracks.

    The researchers then sought to bypass that step ? to stimulate the chemical chain-reaction further downstream. The first compound they tested - forskolin ? worked and it worked without the need for UV rays. The drug stimulated the same tanning pathway but started downstream from the blockage in fair-skinned mice.

    Unlike the sunless tanning lotions available on the market today that dye the skin the forskolin lotion stimulated the natural tanning process.

    "The drug that we?re using is not a coloring agent per se, rather it?s stimulating the melanocytes in a fashion exactly mimicking the very same pathway the tanning response would stimulate," Dr. Fisher said.

    PROTECTIVE AS WELL

    There was a benefit in the forskolin-induced tanning.

    "The darkening is very profound and functional in the sense that it protected against UV radiation," Dr. Fisher said.

    In tests designed to mimic an hour of noontime sun exposure in Florida, the forskolin-darkened mice were protected against sunburn and against the genetic damage that can lead to skin cancer. But human skin is not mouse skin. For one thing, it?s considerably thicker than mouse skin so the cream may not penetrate as well.

    This research is many years away from producing a cream for humans.

    "Forskolin is the first drug we attempted, but I don?t believe that it will necessarily be the best drug for humans. It?s almost never the case that the first one you try is the best one," Dr. Fisher said.

    Forskolin creams are not approved for sale in the United States although the homeopathic product is available in pill form. But Dr. Fisher warns there?s no reason to believe digested forskolin would have the same effect on the skin.

    "This is by no means an advertisement for people to go out and start putting this on their skins [?] When there are things that are biologically active and we don?t understand them I am not in favor of people experimenting," Dr. Fisher said.

    SOURCES:

    Nature September 21, 2006.
    Cancerpage.com telephone interview with Dr. David E. Fisher on September 19, 2006
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  11. #11
    Banned Adrenolin's Avatar
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    Originally Posted by dsade View Post
    tyrosine converts to l-dopa, which then converts to melanin.

    Skip the middleman and just use Atomic Meltdown, which contains both.
    Yes I know. I have used your products, and they work very well. I hear you are coming out with some new tanning/skin products soon..
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  12. #12
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    Originally Posted by Faktum View Post
    I've heard that Foroskolin might help with tanning, any experiences with that?
    STRICTLY from a "tanning instead of burning" perspective, it's LEGIT. Also pick up some Sesamin and Zinc.
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  13. #13
    brb I'm cutting Grouch714's Avatar
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    Originally Posted by pu12en12g View Post
    STRICTLY from a "tanning instead of burning" perspective, it's LEGIT. Also pick up some Sesamin and Zinc.
    What the...Strong bump there PT
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    Registered User shavani's Avatar
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    Originally Posted by Grouch714 View Post
    What the...Strong bump there PT
    I guess the key is penetrating the skin and hair follicles to make it work. Is there a less irritating alternative for dmso. Like melanotan, it would probably also affect the color of new hair growth if it's working?
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    Registered User shavani's Avatar
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    [QUOTE=ToshiroMifune;306480771]In order ot metabolize into melanin, tyrosine needs to interact with:

    B9
    B3
    C
    S-AM
    cuprum


    Never heard about this combo before, tried tyrosine without the s-am and cuprum, so maybe the combo will do it?????
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    my foreskin came pre-tanned
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