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    Arrow L-Huperzine vs ********(prescription only) for study purposes

    I have read L-Huperzine being compared to the prescription only ********, which many students use, illicitly, for concentration aid in studying for exams. Any experience with it? Is it comparable to ********? Any other legal, non-prescription nootropics or "smart drugs" that are comparable to ******** or worth purchasing?

    Any help or info would be greatly appreciated as finals are soon approaching and concentration levels are currently very low.

    Thanks
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    Originally Posted by tnick View Post
    I have read L-Huperzine being compared to the prescription only ********, which many students use, illicitly, for concentration aid in studying for exams. Any experience with it? Is it comparable to ********? Any other legal, non-prescription nootropics or "smart drugs" that are comparable to ******** or worth purchasing?

    Any help or info would be greatly appreciated as finals are soon approaching and concentration levels are currently very low.

    Thanks


    Huperzine Introduction

    A Chinese medicine with use dating back hundreds (if not thousands) of years, healers have used the moss Huperzia serrata as part of their medical armamentarium. The moss is found in northern areas of China and has been employed as a fever and inflammation remedy. While some research backs up the historical applications of this medicinal moss, modern science has uncovered far more uses for this plant. More specifically, an alkaloid extract of the moss, known as huperzine A, has impressive effects on conditions involving the brain.

    Huperzine A appears to work on areas of memory and can possibly benefit those with loss of short term memory; as well as in conditions of long term memory loss, such as Alzheimer�s disease. Other information relating to its usefulness in treating fevers and inflammation (historical uses) remain to be elucidated by modern research. However, given the wisdom of thousands of years of efficient usage, huperzine A may indeed be helpful for such conditions.



    Huperzine Food Sources

    Parts Used
    The extract of the moss, huperzine A, is classified as an alkaloid chemical. Huperzine A is derived from two different types of Chinese club moss, Huperzia serrata and Lycopodium selago. [1]

    Huperzine Uses
    Huperzine A directly affects the concentration of a particular neurotransmitter in the brain known as acetylcholine. [2, 3] This medicine works by stopping or slowing the enzyme (acetylcholinesterase, AChE) responsible for breaking down this neurotransmitter for a specified period of time; hence it is known as a reversible acetylcholinesterase inhibitor.


    Under normal conditions in the brain, acetylcholine is released and acts upon specific neurons. Once it has performed its function, the enzyme acetylcholinesterase comes along and �sweeps up� the remaining acetylcholine. Huperzine A effectively slows this action, leaving acetylcholine around for longer periods of time. Scientists believe this may be the reason why Huperzine A has positive effects on certain brain conditions.

    Huperzine A is thought to act on AChE for up to 3 hours, and may be more effective than certain pharmaceutical AChE inhibitors (i.e. tacrine, Cognex or donzepril, Aricept). [4, 5] In one particular study, huperzine A was shown to be 64 times more effective than one of these medications (tacrine), and to be better distributed in the brain than this drug. [1] In addition to working as well as commonly prescribed drugs, huperzine A can protect brain cells in certain conditions as well. For example, glutamate is an amino acid that can become toxic to brain cells when it reaches a certain concentration; huperzine A also protects against glutamate-induced neuronal damage. [4] Huperzine A is protective against another type of experimental neurotoxin, N-methyl-D-aspartate, or NMDA. [6, 7] Huperzine A is protective against certain seizure-inducing nerve agents as well. [8]

    Areas where huperzine A excels also includes improving memory function in healthy individuals. In one study, highlighting school children that complained of poor memory, huperzine supplementation was shown to improve memory after only four weeks of supplmentation. [9]

    In treatments of dementia, huperzine A supplementation has been shown to improve the memory, behavior, and cognitive function in people with Alzheimer�s disease, brain damage caused by strokes, and in the very elderly who suffer from senile-induced dementia. [10-12] In these studies, treatment times ranged from two to eight weeks of supplementation.

    Another interesting area of success with huperzine A is within the treatment of the disease myasthenia gravis (MG). MG is an autoimmune condition in which acetylcholine receptors in the muscles are attacked by the person�s own immune system. By administering huperzine A, muscle weakness was delayed in MG patients who received the medicine by intramuscular injection. [1] Compared to neostigmine, a commonly used drug for this condition, huperzine A had a longer duration of effect.


    Huperzine Dosages


    Taken orally, huperzine A is dosed from 50 micrograms to 200 micrograms, twice per day. Studies investigating its intramuscular use utilized 400 micrograms per day.


    Huperzine Toxicities and Contraindications

    Huperzine Side effects:
    Some reported side effects of huperzine A supplementation include blurry vision, sweating, nausea, loss of appetite, muscle twitching, and insomnia. [13, 14]


    Conditions in which huperzine A may be contraindicated include pregnancy and lactation; no studies have been performed regarding its safety, however. Other conditions with potential reactions include; cardiovascular disease (huperzine can slow the heart rate), epilepsy (may worsen seizure disorders), ulcers (huperzine can enhance gastric juice secretion), asthma or chronic obstructive pulmonary disease (huperzine may increase lung secretions), and urinary tract obstructions (huperzine may increase secretions here as well).

    Note: Huperzine A, although derived from a plant, is a constituent that has undergone laboratory modification. Avoid confusing prescription names of huperzine A (Cerebra, selagine) with similar-sounding prescription drugs (e.g. Celebrex, Celexa, Cerebyx and selegiline). [15]

    General interactions (supplement, herb, food, lab):
    Huperzine A does not appear to interfere with any other supplements, herbs, foods, or lab tests.

    Huperzine Drug interactions:
    Because of the apparent inhibitory effect of huperzine A on AChE, using it with acetylcholinesterase inhibitor drugs may lead to additive effects. This includes the drugs; tacrine (Cognex), succinylcholine (Anectine, Quelicin), echothiophate (Phospholine Iodide, bethanechol (Urecholine), donepezil (Aricept), edrophonium (Enoln, Reversol, Tensilon), neostigmine (Prostigmin), physostigmine (Antilirium), and pyridostigmine (Mestinon, Regonol).

    Using huperzine A with anticholinergic drugs may decrease the effectiveness of huperzine A, as these drugs counter its effects on acetylcholine. Anticholinergic drugs include: scopolamine, atropine, biperiden (Akineton), benztropine (Cogentin), trihexyphenidyl (Artane), and procyclidine (Kemadrin).


    Using huperzine A with cholinergic drugs (these promote the activity of acetylcholine in the body) may lead to additive effects. These drugs include; bethanechol (Urecholine), donepezil (Aricept), echothiophate (Phospholine Iodide), edrophonium (Enoln, Reversol, Tensilon), neostigmine (Prostigmin), physostigmine (Antilirium), pyridostigmine (Mestinon, Regonol), succinylcholine (Anectine, Quelicin), and tacrine (Cognex).
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    Ive used a ton of Huperzine and ******** type stimulants enough to give you a comaprison. Its not even close. I love Hupa but it gives a completely different feel then something like ********. I would still use Hupa but would look for something else to enhance focus.
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    Originally Posted by VaughnTrue View Post
    Huperzine Introduction

    A Chinese medicine with use dating back hundreds (if not thousands) of years, healers have used the moss Huperzia serrata as part of their medical armamentarium. The moss is found in northern areas of China and has been employed as a fever and inflammation remedy. While some research backs up the historical applications of this medicinal moss, modern science has uncovered far more uses for this plant. More specifically, an alkaloid extract of the moss, known as huperzine A, has impressive effects on conditions involving the brain.

    Huperzine A appears to work on areas of memory and can possibly benefit those with loss of short term memory; as well as in conditions of long term memory loss, such as Alzheimer�s disease. Other information relating to its usefulness in treating fevers and inflammation (historical uses) remain to be elucidated by modern research. However, given the wisdom of thousands of years of efficient usage, huperzine A may indeed be helpful for such conditions.



    Huperzine Food Sources

    Parts Used
    The extract of the moss, huperzine A, is classified as an alkaloid chemical. Huperzine A is derived from two different types of Chinese club moss, Huperzia serrata and Lycopodium selago. [1]

    Huperzine Uses
    Huperzine A directly affects the concentration of a particular neurotransmitter in the brain known as acetylcholine. [2, 3] This medicine works by stopping or slowing the enzyme (acetylcholinesterase, AChE) responsible for breaking down this neurotransmitter for a specified period of time; hence it is known as a reversible acetylcholinesterase inhibitor.


    Under normal conditions in the brain, acetylcholine is released and acts upon specific neurons. Once it has performed its function, the enzyme acetylcholinesterase comes along and �sweeps up� the remaining acetylcholine. Huperzine A effectively slows this action, leaving acetylcholine around for longer periods of time. Scientists believe this may be the reason why Huperzine A has positive effects on certain brain conditions.

    Huperzine A is thought to act on AChE for up to 3 hours, and may be more effective than certain pharmaceutical AChE inhibitors (i.e. tacrine, Cognex or donzepril, Aricept). [4, 5] In one particular study, huperzine A was shown to be 64 times more effective than one of these medications (tacrine), and to be better distributed in the brain than this drug. [1] In addition to working as well as commonly prescribed drugs, huperzine A can protect brain cells in certain conditions as well. For example, glutamate is an amino acid that can become toxic to brain cells when it reaches a certain concentration; huperzine A also protects against glutamate-induced neuronal damage. [4] Huperzine A is protective against another type of experimental neurotoxin, N-methyl-D-aspartate, or NMDA. [6, 7] Huperzine A is protective against certain seizure-inducing nerve agents as well. [8]

    Areas where huperzine A excels also includes improving memory function in healthy individuals. In one study, highlighting school children that complained of poor memory, huperzine supplementation was shown to improve memory after only four weeks of supplmentation. [9]

    In treatments of dementia, huperzine A supplementation has been shown to improve the memory, behavior, and cognitive function in people with Alzheimer�s disease, brain damage caused by strokes, and in the very elderly who suffer from senile-induced dementia. [10-12] In these studies, treatment times ranged from two to eight weeks of supplementation.

    Another interesting area of success with huperzine A is within the treatment of the disease myasthenia gravis (MG). MG is an autoimmune condition in which acetylcholine receptors in the muscles are attacked by the person�s own immune system. By administering huperzine A, muscle weakness was delayed in MG patients who received the medicine by intramuscular injection. [1] Compared to neostigmine, a commonly used drug for this condition, huperzine A had a longer duration of effect.


    Huperzine Dosages


    Taken orally, huperzine A is dosed from 50 micrograms to 200 micrograms, twice per day. Studies investigating its intramuscular use utilized 400 micrograms per day.


    Huperzine Toxicities and Contraindications

    Huperzine Side effects:
    Some reported side effects of huperzine A supplementation include blurry vision, sweating, nausea, loss of appetite, muscle twitching, and insomnia. [13, 14]


    Conditions in which huperzine A may be contraindicated include pregnancy and lactation; no studies have been performed regarding its safety, however. Other conditions with potential reactions include; cardiovascular disease (huperzine can slow the heart rate), epilepsy (may worsen seizure disorders), ulcers (huperzine can enhance gastric juice secretion), asthma or chronic obstructive pulmonary disease (huperzine may increase lung secretions), and urinary tract obstructions (huperzine may increase secretions here as well).

    Note: Huperzine A, although derived from a plant, is a constituent that has undergone laboratory modification. Avoid confusing prescription names of huperzine A (Cerebra, selagine) with similar-sounding prescription drugs (e.g. Celebrex, Celexa, Cerebyx and selegiline). [15]

    General interactions (supplement, herb, food, lab):
    Huperzine A does not appear to interfere with any other supplements, herbs, foods, or lab tests.

    Huperzine Drug interactions:
    Because of the apparent inhibitory effect of huperzine A on AChE, using it with acetylcholinesterase inhibitor drugs may lead to additive effects. This includes the drugs; tacrine (Cognex), succinylcholine (Anectine, Quelicin), echothiophate (Phospholine Iodide, bethanechol (Urecholine), donepezil (Aricept), edrophonium (Enoln, Reversol, Tensilon), neostigmine (Prostigmin), physostigmine (Antilirium), and pyridostigmine (Mestinon, Regonol).

    Using huperzine A with anticholinergic drugs may decrease the effectiveness of huperzine A, as these drugs counter its effects on acetylcholine. Anticholinergic drugs include: scopolamine, atropine, biperiden (Akineton), benztropine (Cogentin), trihexyphenidyl (Artane), and procyclidine (Kemadrin).


    Using huperzine A with cholinergic drugs (these promote the activity of acetylcholine in the body) may lead to additive effects. These drugs include; bethanechol (Urecholine), donepezil (Aricept), echothiophate (Phospholine Iodide), edrophonium (Enoln, Reversol, Tensilon), neostigmine (Prostigmin), physostigmine (Antilirium), pyridostigmine (Mestinon, Regonol), succinylcholine (Anectine, Quelicin), and tacrine (Cognex).

    Thanks alot, great info.

    Originally Posted by Sldge View Post
    Ive used a ton of Huperzine and ******** type stimulants enough to give you a comaprison. Its not even close. I love Hupa but it gives a completely different feel then something like ********. I would still use Hupa but would look for something else to enhance focus.

    Any suggestions? Even if they are "theoretically supplement X would help but is prescription only" (other than ********)
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    Originally Posted by tnick View Post
    Thanks alot, great info.

    Any suggestions? Even if they are "theoretically supplement X would help but is prescription only" (other than ********)
    I know it sounds like a plug but a lot of other people have said the exact same thing without knowing how I felt about it at the time. Adrenalean sounds perfect for what you are talking about. If you do some searches youll see plenty of people talking about the great focus.
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    Talking Cut up whilst I study!!

    Originally Posted by Sldge View Post
    I know it sounds like a plug but a lot of other people have said the exact same thing without knowing how I felt about it at the time. Adrenalean sounds perfect for what you are talking about. If you do some searches youll see plenty of people talking about the great focus.

    So I can cut up and increase concentration at the same time!! I looked over the ingredients and I can see your point. Of the 710mg proprietary blend can you say how much L-Huperzine A there is in it. Or if you cannot, then can you say, assuming i want to consume around 400mcg of L-Huperzine A a day, whether or not it would be necessary to buy some additional L-Huperzine A?

    Also do you think I would need to supplement on this for a certain period of time before it begins effect?

    Any other options anyone?
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    bump for brains..........
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    ******** + starbucks = 10 page papers and A+ Exams!

    Trust me, I chemically engineered every good grade I got LOL
    keep it simple, keep it basic, keep it heavy
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    Originally Posted by dalvare1 View Post
    ******** + starbucks = 10 page papers and A+ Exams!

    Trust me, I chemically engineered every good grade I got LOL
    wtf.


    how come i'm the only college student in america who has never tried this stuff?



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    Originally Posted by dalvare1 View Post
    ******** + starbucks = 10 page papers and A+ Exams!

    Trust me, I chemically engineered every good grade I got LOL
    Couldnt agree with u more. But im over in the UK and its a little harder to get a hold of than I hear it is in the US. As far as I know cant be got online (research purposes off course). I found some but because its so close to exams they're going for 5pounds/pill thats 10bucks a go!!!
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    Originally Posted by VaughnTrue View Post
    wtf.


    how come i'm the only college student in america who has never tried this stuff?



    dammit man.
    hahaha, I had a TON of it. Just make friends with someone crazy..... errrrr ok ill stop there.......



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    Something without the buzz

    Try recommending provigil to your doctor. It does NOT have any of the speediness associated with amphetamines (such as adderal) but does help concentration and wakefullness.

    If you like the jitters then ask your doctor for Ritalin or Desoxyn (I'm assuming you have a real need for this stuff).
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    Vaughn did you see the inside joke there? Ahahahhaa thats too funny man.
    keep it simple, keep it basic, keep it heavy
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    Originally Posted by dalvare1 View Post
    Vaughn did you see the inside joke there? Ahahahhaa thats too funny man.
    lol yes, yes i caught it. jackass
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    To make me fret or make me frown
    I had strings, but now I'm free
    I got no strings on me
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  16. #16
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    Originally Posted by VaughnTrue View Post
    lol yes, yes i caught it. jackass
    OK good, just making sure
    keep it simple, keep it basic, keep it heavy
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    Are you Driven? Sldge's Avatar
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    Originally Posted by tnick View Post
    So I can cut up and increase concentration at the same time!! I looked over the ingredients and I can see your point. Of the 710mg proprietary blend can you say how much L-Huperzine A there is in it. Or if you cannot, then can you say, assuming i want to consume around 400mcg of L-Huperzine A a day, whether or not it would be necessary to buy some additional L-Huperzine A?

    Also do you think I would need to supplement on this for a certain period of time before it begins effect?
    I cant release the amount of HupA contained in Adrenalean but I dont think youll need anymore. You can feel the effect on the first or second dose but it really becomes apparent by the 3rd day in those not very sensitive.
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  18. #18
    Improve your Mind CognitiveNutrition's Avatar
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    Originally Posted by tnick View Post
    I have read L-Huperzine being compared to the prescription only ********, which many students use, illicitly, for concentration aid in studying for exams. Any experience with it? Is it comparable to ********? Any other legal, non-prescription nootropics or "smart drugs" that are comparable to ******** or worth purchasing?

    Any help or info would be greatly appreciated as finals are soon approaching and concentration levels are currently very low.

    Thanks
    L-Huperzine A is stronger for memory but far weaker for focus.

    Deprenyl is what you want to try.
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