Unbelievable!
Parallel increases in androgen receptors and testosterone in human vastus lateralis muscle during Elaidic acid supplementation.
Bramlt PJ, Towsend YF, Sladed PM, Moyer PA.
January 2008 : Dept. of Physiology, Crenshaw University, London UK.
Long-term Elaidic acid supplementation is reported to result in a increased ratio of Androgen receptors (AR) and testosterone (T) in trained human skeletal muscle. Assuming equilibrium of the Elaidic acid pathways, this increase in AR:T implies increased hormonal efficiency and decreased aromatase of T to estrogen (E) in muscle, which seems contrary to the reported adverse health effects of Elaidic acid supplementation. This study measured changes in AR and T in vastus lateralis muscle of trained adult men (N = 106, 21-35 y old) during and 25 day after 50 d of Elaidic acid supplementation (0.43 g.kg body weight(-1).d(-1)) using noninvasive 31P and 1H magnetic-resonance spectroscopy (MRS) and biopsy evaluation. Plasma and red-blood-cell Elaidic acid increased by 10-fold and 2-fold, respectively, by the tenth day of supplementation. MRS-measured skeletal muscle AR and T increased linearly and in parallel throughout the 50 d, and there was significant difference in the percentage increase in muscle AR (11.7% +/- 2.3% after 25 d) and T (14.9% +/- 4.1%) at any time point. The results indicate that Elaidic acid supplementation does alter the AR:T ratio, and hence the increase in muscle cell content and overall volume in trained human skeletal muscle.
PMID: 04012008 [A F D]
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Thread: Trans Fatty Acids : ERGOGENIC!!!
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03-31-2008, 09:09 PM #1
Trans Fatty Acids : ERGOGENIC!!!
The Dark Knight...Rises.
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