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    What is the rationale of glycerol intake for a bodybuilder

    This subject came up on another thread. Now i have not studied glycerol metabolism in great detail so i may be missing something here.

    But as far as i know glycerol is something that helps increase blood volume by creating an osmotic effect in the blood that draws fluids from intracellular stores. This is why it is useful for sporting events in which lowered blood volume due to dehydration is an issue.But for a bodybuilder you would think that drawing water out of muscle cells and into the blood is counterproductive to anabolism and strength.


    Now I could still be wrong, and there may be some strange uptake of glycerol into muscle cells. I know glycerol is taken up by fat cells to make triglycerides, and by the liver to be catabolized into stuff that enters into the glycolytic and gluconeogenisis pathways.

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    Perhaps one of the Controlled Labs reps could jump on this to provide the scientific benefit to a bodybuilder. I know I have used their GlycerGrow product in the past, but don't have the knowledge you're looking for. All I have is the anecdotal (it made me stronger, fuller) evidence... Interested in this thread as well...

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    Originally Posted by Patrick Arnold View Post
    This subject came up on another thread. Now i have not studied glycerol metabolism in great detail so i may be missing something here.

    But as far as i know glycerol is something that helps increase blood volume by creating an osmotic effect in the blood that draws fluids from intracellular stores. This is why it is useful for sporting events in which lowered blood volume due to dehydration is an issue.But for a bodybuilder you would think that drawing water out of muscle cells and into the blood is counterproductive to anabolism and strength.


    Now I could still be wrong, and there may be some strange uptake of glycerol into muscle cells. I know glycerol is taken up by fat cells to make triglycerides, and by the liver to be catabolized into stuff that enters into the glycolytic and gluconeogenisis pathways.
    I mean, you're Patrick Arnold, shouldn't you tell us?

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    Hmm...interesting...*subscribes*

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    Originally Posted by demonwareltd View Post
    Perhaps one of the Controlled Labs reps could jump on this to provide the scientific benefit to a bodybuilder. I know I have used their GlycerGrow product in the past, but don't have the knowledge you're looking for. All I have is the anecdotal (it made me stronger, fuller) evidence... Interested in this thread as well...
    Or Daniel, once he's unbanned.

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    Originally Posted by demonwareltd View Post
    All I have is the anecdotal (it made me stronger, fuller) evidence... Interested in this thread as well...
    x2....I've successfully used Glycergrow, and have plans to use it again.
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    i dirnk GMS and PowerPump 7(10g Glycerol) and its a good pump and hydration

    you guys should add some to Clear Shot, for pumps, and its water soluble and probably cheap

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    Originally Posted by steam View Post
    i dirnk GMS and PowerPump 7(10g Glycerol) and its a good pump and hydration

    you guys should add some to Clear Shot, for pumps, and its water soluble and probably cheap
    Thanks for the suggestion, but I don't think that was the point of this thread...

  9. #9
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    Originally Posted by MBSowards View Post
    Or Daniel, once he's unbanned.
    Is Dan really banned or did he just type that?

    I saw his green light on this morning...
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    Originally Posted by TheUnlikelyToad View Post
    Is Dan really banned or did he just type that?

    I saw his green light on this morning...
    you can log in, but can't post.
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    Originally Posted by TheUnlikelyToad View Post
    Is Dan really banned or did he just type that?

    I saw his green light on this morning...
    banned for this

    http://forum.bodybuilding.com/showth...hp?t=106853261

  12. #12
    Banned Patrick Arnold's Avatar
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    Originally Posted by steam View Post
    i dirnk GMS and PowerPump 7(10g Glycerol) and its a good pump and hydration
    i have a very sophisticated method of staying well hydrated during a workout

    its called the water fountain

    bodybuilders do not have to worry about hydration. Triathletes and marathon runners do.

    I can't see the rationale for a bodybuilder using glycerol, sorry.

    I know i know. check the logs

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    Originally Posted by Patrick Arnold View Post
    i have a very sophisticated method of staying well hydrated during a workout

    its called the water fountain
    Please continue about this "water fountain" you speak of.

    I have bought GMS, I actually have 2 tubs of it, but I do not use it anymore. It didn't really work for me, and it's considered a saturated fat. I know SizeON has GMS in it as well.
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    wow very interesting...

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    I use glycerine as part of my 'carbup' for competition and it aids in the 'shrinkwrapped' look. I have not used it as part of my regular training protocol thus far, though.
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    It was my understanding that glycerol could penetrate the membrane without active transport along its [conc] gradient. Although in retrospect, it does have a low membrane permeability coefficient.
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    Originally Posted by dvsness View Post
    I use glycerine as part of my 'carbup' for competition and it aids in the 'shrinkwrapped' look. I have not used it as part of my regular training protocol thus far, though.

    after reading more it appears that glycerol can be stored substantially in between muscle cells (interstitial space). Which may actually draw water from the blood into the space between muscle cellls. That may of been what helped you acheive the look

    But from a muscle building standpoint this might actually be detrimental. The glycerol outside of the cells would tend to draw water out of the muscle cells through osmosis. That is really want you do NOT want i would think.

    Could be this glycerol pump is a "false Pump", and actually counterproductive

    hey, don't shoot the messenger....

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    Banned Patrick Arnold's Avatar
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    Originally Posted by triathelete04 View Post
    It was my understanding that glycerol could penetrate the membrane without active transport along its [conc] gradient. Although in retrospect, it does have a low membrane permeability coefficient.

    cell membranes are lipophilic. glycerol is lipophobic. i can't see it diffusing into the cells to any significant degree. And one thing i read indicated that most muscle glycerol is interstitial

  19. #19
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    Originally Posted by SCDiesel23 View Post
    Please continue about this "water fountain" you speak of.
    My gym has one


    Back on topic: I have never used glycerol before but I am interested in what comes out of this thread.
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  20. #20
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    Originally Posted by Xc View Post

    Back on topic: I have never used glycerol before but I am interested in what comes out of this thread.
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    I've tried NX Labs's Plasmavol which has a bit of glycerol and to put it bluntly, I felt like **** while taking it. I was constantly drinking water and at the end of the workout was feeling thirsty still and bloated. So much for being hydrated. Not sure if this was due to the glycerol, the creatine or the mannitol tho. I know mannitol is a diuretic so it could've been that but I ripped through 3 liters of water in a half hour and was dying, that was insane. It's not under bb.com's store either so I assume it wasn't recieved so well after all.
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    Originally Posted by Patrick Arnold View Post
    I know i know. check the logs, bro!
    fixed.

    c'mon PA, you know the drill!
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  23. #23
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    An excerpt from this ARTICLE which doesn't neccesarily talk alot about glycerol, but I noticed this...


    At baseline, interstitial glycerol was strikingly higher (P < 0.0001) in muscle (3710 microM) and adipose tissue (2760 microM) compared with plasma (87 microM), whereas interstitial glucose (muscle 3.3, fat 3.6 mM) was lower (P < 0.01) than plasma levels (4.8 mM).

    I'll inspect more of it and might post some more If i find anything
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    Originally Posted by Patrick Arnold View Post
    cell membranes are lipophilic. glycerol is lipophobic. i can't see it diffusing into the cells to any significant degree. And one thing i read indicated that most muscle glycerol is interstitial
    Glycerol-conducting membrane channel perhaps?
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  26. #26
    cutting Handsome Maxout's Avatar
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    The product you brought up on the bottom of page 1 got discontinued too. Hmm...

    http://www.bodybuilding.com/store/nx/plasma.html

    ???
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  27. #27
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    i don't know much

    but... would it help get more of the supplements you are taking into the muscle... just a little input, i've never used a product like this before...


    quoted on cl glycergrow page...

    In laymen's terms, taking glycerol in supplemental form quickly improves hydration and the absorption of other supplements that are taken with it. The end result is faster delivery of nutrients when and where you need them the most and the prolonged "pump effect" during your workouts.

    i know this is broscience, but it sounds like its a good thing






    i should probably delete this, the stuff you guys are talking about is wayyy beyond me... i'm the finance/accountant type
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  28. #28
    Banned Patrick Arnold's Avatar
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    Originally Posted by benjamin0 View Post
    An excerpt from this ARTICLE which doesn't neccesarily talk alot about glycerol, but I noticed this...





    interstitial is the key word

  29. #29
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    Originally Posted by Feny View Post
    but... would it help get more of the supplements you are taking into the muscle... just a little input, i've never used a product like this before...


    quoted on cl glycergrow page...

    In laymen's terms, taking glycerol in supplemental form quickly improves hydration and the absorption of other supplements that are taken with it. The end result is faster delivery of nutrients when and where you need them the most and the prolonged "pump effect" during your workouts.

    i know this is broscience, but it sounds like its a good thing

    broscience is always good!! sells alot more supplements than real science ever did

  30. #30
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    Originally Posted by Feny View Post
    but... would it help get more of the supplements you are taking into the muscle... just a little input, i've never used a product like this before...


    quoted on cl glycergrow page...

    In laymen's terms, taking glycerol in supplemental form quickly improves hydration and the absorption of other supplements that are taken with it. The end result is faster delivery of nutrients when and where you need them the most and the prolonged "pump effect" during your workouts.

    i know this is broscience, but it sounds like its a good thing
    x2 i also read that it increases the absortion of nutrients, this is why you need to take advantage after your workout and have a good pwo meal when you are still all pump up.

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