Vitamin B-Complex...(and Daily Vitamins)

[kerplunk]

Recently, I've been reading a lot on vitamins (Dinoiii's Material) and healthy supplementation and it appears to me that a b-complex would be useful dosing it through out the day with your 3 major meals. There are a lot of these b-complexes available and after looking at each one the only "good" one I found was the Life Extension Complete B-Complex - http://www.bodybuilding.com/store/le...ebcomplex.html

Now my only negative remark regarding this one is the form of b-12 it contains, as apparently Cyan most be converted to a form usable by the body. Are there better b-complexes?

Also who uses them? What other vitamins and multis do you take. Im looking for a new vitamin regimen and have come across Dr. Housers ACES and b-complex recommendations

(Found Here = http://blog.bodybuilding.com/dinoiii...in-mvi-debate/ )

I understand some of you take the cheap $10 multis, but post up the ingredient profile!

[kerplunk]

nobody?

[eldawg]

http://www.bodybuilding.com/store/country/co.html
http://www.bodybuilding.com/store/kal/coenzyme.html

If you want something with just B12:

http://www.bodybuilding.com/store/now/brainb12.html
http://www.bodybuilding.com/store/now/instant.html

[kerplunk]

http://www.bodybuilding.com/store/country/co.html
http://www.bodybuilding.com/store/kal/coenzyme.html

If you want something with just B12:

http://www.bodybuilding.com/store/now/brainb12.html
http://www.bodybuilding.com/store/now/instant.html

Thanks eldawg.

But theres a few reasons as to why I like the life extension compared to the others.

1) High dose of B5, which is good for the skin and acne
2) 3 Caps per day, one with each meal.


Now my question is, would the amount of B-12 in the life extension be sufficient?

[eldawg]

You could always grab the NOW Brain B12 (like $7 for 100 lozenges) and take one of those per day if you want more B12.

I agree that the LEF product is pretty good.

[sonicology]

But theres a few reasons as to why I like the life extension compared to the others.

I would also add that LEF are one of the very few supplement companies I actually trust.

[RavensFan2k3]

Thanks eldawg.

But theres a few reasons as to why I like the life extension compared to the others.

1) High dose of B5, which is good for the skin and acne
2) 3 Caps per day, one with each meal.


Now my question is, would the amount of B-12 in the life extension be sufficient?

The only thing I don't like about the one you posted is how the Vitamin B6 isnt in P5P form, while the others have that form.

[kerplunk]

The only thing I don't like about the one you posted is how the Vitamin B6 isnt in P5P form, while the others have that form.

what makes the P5P better?

[kerplunk]

You could always grab the NOW Brain B12 (like $7 for 100 lozenges) and take one of those per day if you want more B12.

I agree that the LEF product is pretty good.

Its not that I want more, I want to know if the Cyano in the LEF is enough.

[eldawg]

Will you be taking a multi at all?

[kerplunk]

Will you be taking a multi at all?

Thats what im trying to figure out, cause then i'd be afraid of ODing on B6.

[in10city]

what makes the P5P better?

Pyridoxal 5'-phosphate is the active coenzyme form. More or less analagous to methylcobalamin and 5-deoxyadenosyl cobalamin.

Thats what im trying to figure out, cause then i'd be afraid of ODing on B6.

I haven't seen anything regarding P5P being associated with toxicity.

I have only seen toxicity information related to the pyridoxine form and nothing below the intake of 200 mg pyridoxine daily, and a few cases between 200-500 mg. One hypothesis I've seen is that pyridoxine toxicity is caused by it exceeding the liver's ability to phosphorylate pyridoxine to P5P.

[Phosphate bond]

Recently, I've been reading a lot on vitamins (Dinoiii's Material) and healthy supplementation and it appears to me that a b-complex would be useful dosing it through out the day with your 3 major meals.

Now my only negative remark regarding this one is the form of b-12 it contains, as apparently Cyan most be converted to a form usable by the body. Are there better b-complexes?

It does make more sense to me to split up the B-complex with meals.

active B-12 in the body is either in adenosyl cobalamin form (to convert methylmalonic acid to succinyl COA) or methyl cobalamin to convert homocysteine back to methionine.

However, cyano cobalamin or hydroxy cobalamin should have no problem converting to either active form. This will just happen naturally as the body sees fit.

[kerplunk]

It does make more sense to me to split up the B-complex with meals.

active B-12 in the body is either in adenosyl cobalamin form (to convert methylmalonic acid to succinyl COA) or methyl cobalamin to convert homocysteine back to methionine.

However, cyano cobalamin or hydroxy cobalamin should have no problem converting to either active form. This will just happen naturally as the body sees fit.

Thank you PB. Thats exactly what I wanted to know.

[kerplunk]

Pyridoxal 5'-phosphate is the active coenzyme form. More or less analagous to methylcobalamin and 5-deoxyadenosyl cobalamin.



I haven't seen anything regarding P5P being associated with toxicity.

I have only seen toxicity information related to the pyridoxine form and nothing below the intake of 200 mg pyridoxine daily, and a few cases between 200-500 mg. One hypothesis I've seen is that pyridoxine toxicity is caused by it exceeding the liver's ability to phosphorylate pyridoxine to P5P.

Thank you in10city. Even though the form of B6 in this B-complex is Pyridoxine HCl it still looks like its the only way to go. 3 caps a day makes it easy with meal, great price, and perfect amounts of each vit.

[Cable Curling CincoUno]

cant get it on bb.com but look into some of AOR's products
I'm ordering the advanced b-complex and total E from the line to meet my B & E. I follow Dr. Houser's recommendations as well and as hes stated the only B-vit overdose potential lies in niacin but it takes upwards of 2gs daily to reach toxic levels.
he also recommends a multi-mineral

[Cable Curling CincoUno]

Thats what im trying to figure out, cause then i'd be afraid of ODing on B6.

eff multis

[kerplunk]

cant get it on bb.com but look into some of AOR's products
I'm ordering the advanced b-complex and total E from the line to meet my B & E. I follow Dr. Houser's recommendations as well and as hes stated the only B-vit overdose potential lies in niacin but it takes upwards of 2gs daily to reach toxic levels.

Yea but isnt niacin broken up into multiple parts, nicomide and niacinamide? I took supplemental nicomide for acne and along with my NOW Adam. Wouldnt you have to OD on one or the other or would it be ODing on the two combined?

Please someone correct me if im wrong. Learning is the best thing for me right now.

[Cable Curling CincoUno]

Yea but isnt niacin broken up into multiple parts, nicomide and niacinamide? I took supplemental nicomide for acne and along with my NOW Adam. Wouldnt you have to OD on one or the other or would it be ODing on the two combined?

Please someone correct me if im wrong. Learning is the best thing for me right now.

regardless is there anyway your approaching that total? thats a hell of a lot. I pop a bcomplex with most meals and I'm not worried

[kerplunk]

regardless is there anyway your approaching that total? thats a hell of a lot. I pop a bcomplex with most meals and I'm not worried

I think two nicomide tabs a day + a now adam 1.2ish grams. So yea, im not that close.

[kerplunk]

With meals im thinking the optimal dosing of pills for me will end up being. 1 B-complex, 2 Fish Oils, and 1 Vit C with breakfast and dinner (away from workout time).

[Cable Curling CincoUno]

Are you going to be taking E, A, selenium and some sort of muli-mineral as well?

[in10city]

I think two nicomide tabs a day + a now adam 1.2ish grams. So yea, im not that close.

When you start chronically taking 2 to 3+ grams a day of combined niacin, that's when hepatotoxicity will be a concern.

[Peter LeDrew]

cant get it on bb.com but look into some of AOR's products
I'm ordering the advanced b-complex and total E from the line to meet my B & E. I follow Dr. Houser's recommendations as well and as hes stated the only B-vit overdose potential lies in niacin but it takes upwards of 2gs daily to reach toxic levels.
he also recommends a multi-mineral

Yeah for the best in B's look no further than once again AOR.
http://www.aor.ca/int/products/advanced_b.php
http://www.aor.ca/int/related_research/advanced_b.php

I have read that B6 is possibly the one to most be careful with... avoiding doses much greater than 100-200mg long term.
http://en.wikipedia.org/wiki/Vitamin_B6
http://en.wikipedia.org/wiki/Pyridoxal_5%27-phosphate

[in10city]

It does make more sense to me to split up the B-complex with meals.

active B-12 in the body is either in adenosyl cobalamin form (to convert methylmalonic acid to succinyl COA) or methyl cobalamin to convert homocysteine back to methionine.

However, cyano cobalamin or hydroxy cobalamin should have no problem converting to either active form. This will just happen naturally as the body sees fit.

...

http://www.metadocs.com/pdf/pp_B6_B12.pdf

Methylcobalamin, while an effective oral form of B12, has not demonstrated superiority over cyanocobalamin and does not nearly have a similar breadth of research. Cyanocobalamin and methylcobalamin are generally considered clinically equivalent.

Methylcobalamin supporters state its superiority as it is the primary circulatory form and acts as a methyl donor. Adenosylcobalamin, however, accounts for 70% of cobalamin stored in the liver, the major storage site for B12, while methylcobalamin accounts for only 1% to 3%. It is also argued that cyanocobalamin is poorly converted into its active forms and releases cyanide into circulation, neither of these statements is supported by research.

[dinoiii]

I'd encourage further exploration of the methylcobalamin research personally.



D_

[RavensFan2k3]

Yea but isnt niacin broken up into multiple parts, nicomide and niacinamide? I took supplemental nicomide for acne and along with my NOW Adam. Wouldnt you have to OD on one or the other or would it be ODing on the two combined?

Please someone correct me if im wrong. Learning is the best thing for me right now.

hey are you feeling a lose of libido while on NOW ADAM?

[kerplunk]

Yeah for the best in B's look no further than once again AOR.
http://www.aor.ca/int/products/advanced_b.php
http://www.aor.ca/int/related_research/advanced_b.php

I have read that B6 is possibly the one to most be careful with... avoiding doses much greater than 100-200mg long term.
http://en.wikipedia.org/wiki/Vitamin_B6
http://en.wikipedia.org/wiki/Pyridoxal_5%27-phosphate

That does look real good, but I do not see anywhere selling it.

[kerplunk]

hey are you feeling a lose of libido while on NOW ADAM?

No, not at all. Im having no problems whatsoever.

[kerplunk]

Are you going to be taking E, A, selenium and some sort of muli-mineral as well?

Yes! I'll be posting that momentarily. I've found a product only with ACES at a great price.