Reply
Results 1 to 17 of 17
  1. #1
    Registered User philc21's Avatar
    Join Date: Jan 2006
    Age: 37
    Posts: 9
    Rep Power: 0
    philc21 has no reputation, good or bad yet. (0)
    philc21 is offline

    Any side effects from too much BCAA's

    Is there anything bad that can occur from taking too many BCAA's or will they just simple flush out when they are not used.
    Reply With Quote

  2. #2
    Godzilla JustinKim943's Avatar
    Join Date: Jan 2006
    Location: Gym
    Age: 35
    Posts: 539
    Rep Power: 288
    JustinKim943 will become famous soon enough. (+50) JustinKim943 will become famous soon enough. (+50) JustinKim943 will become famous soon enough. (+50) JustinKim943 will become famous soon enough. (+50) JustinKim943 will become famous soon enough. (+50) JustinKim943 will become famous soon enough. (+50) JustinKim943 will become famous soon enough. (+50) JustinKim943 will become famous soon enough. (+50) JustinKim943 will become famous soon enough. (+50) JustinKim943 will become famous soon enough. (+50) JustinKim943 will become famous soon enough. (+50)
    JustinKim943 is offline
    yes, it will make u freakishly HUGE.

    Haha, actually i'm not really sure if there are any bad sideaffects if u take it with alotta water. Someone back me up on this.
    Non-Rep Coalition? "Bias Free Since 2003"
    Reply With Quote

  3. #3
    Registered User young_squatter's Avatar
    Join Date: Sep 2005
    Age: 36
    Posts: 17,873
    Rep Power: 2981
    young_squatter is a glorious beacon of knowledge. (+2500) young_squatter is a glorious beacon of knowledge. (+2500) young_squatter is a glorious beacon of knowledge. (+2500) young_squatter is a glorious beacon of knowledge. (+2500) young_squatter is a glorious beacon of knowledge. (+2500) young_squatter is a glorious beacon of knowledge. (+2500) young_squatter is a glorious beacon of knowledge. (+2500) young_squatter is a glorious beacon of knowledge. (+2500) young_squatter is a glorious beacon of knowledge. (+2500) young_squatter is a glorious beacon of knowledge. (+2500) young_squatter is a glorious beacon of knowledge. (+2500)
    young_squatter is offline
    No.
    New 5/3/1 Strength Journal:
    http://forum.bodybuilding.com/showthread.php?t=152156313&p=1031620863#post1031620863
    Reply With Quote

  4. #4
    Registered User uknowmeman's Avatar
    Join Date: Jan 2005
    Posts: 275
    Rep Power: 244
    uknowmeman has no reputation, good or bad yet. (0) uknowmeman has no reputation, good or bad yet. (0) uknowmeman has no reputation, good or bad yet. (0) uknowmeman has no reputation, good or bad yet. (0) uknowmeman has no reputation, good or bad yet. (0) uknowmeman has no reputation, good or bad yet. (0) uknowmeman has no reputation, good or bad yet. (0) uknowmeman has no reputation, good or bad yet. (0) uknowmeman has no reputation, good or bad yet. (0) uknowmeman has no reputation, good or bad yet. (0) uknowmeman has no reputation, good or bad yet. (0)
    uknowmeman is offline
    Maybe an upset stomach? That's about the worst I could think of.
    Reply With Quote

  5. #5
    becoming godsized! bodybuilder45's Avatar
    Join Date: Jan 2005
    Location: Phoenix, Arizona, United States
    Age: 39
    Posts: 2,412
    Rep Power: 555
    bodybuilder45 has a spectacular aura about. (+250) bodybuilder45 has a spectacular aura about. (+250) bodybuilder45 has a spectacular aura about. (+250) bodybuilder45 has a spectacular aura about. (+250) bodybuilder45 has a spectacular aura about. (+250) bodybuilder45 has a spectacular aura about. (+250) bodybuilder45 has a spectacular aura about. (+250) bodybuilder45 has a spectacular aura about. (+250) bodybuilder45 has a spectacular aura about. (+250) bodybuilder45 has a spectacular aura about. (+250) bodybuilder45 has a spectacular aura about. (+250)
    bodybuilder45 is offline
    i thought i remember reading somewhere that creating a huge imbalance of BCAA's in comparison to other amino acids can cause depression. i think someone posted that on AM. however, i have never noticed this or seen others report this problem. i would consider BCAA's one of the safer supplements for sure.
    Reply With Quote

  6. #6
    The Next Jason Voorhees Da Main Man's Avatar
    Join Date: May 2005
    Location: Australia
    Age: 41
    Posts: 4,756
    Rep Power: 849
    Da Main Man is a jewel in the rough. (+500) Da Main Man is a jewel in the rough. (+500) Da Main Man is a jewel in the rough. (+500) Da Main Man is a jewel in the rough. (+500) Da Main Man is a jewel in the rough. (+500) Da Main Man is a jewel in the rough. (+500) Da Main Man is a jewel in the rough. (+500) Da Main Man is a jewel in the rough. (+500) Da Main Man is a jewel in the rough. (+500) Da Main Man is a jewel in the rough. (+500) Da Main Man is a jewel in the rough. (+500)
    Da Main Man is offline
    Originally Posted by bodybuilder45
    i thought i remember reading somewhere that creating a huge imbalance of BCAA's in comparison to other amino acids can cause depression. i think someone posted that on AM. however, i have never noticed this or seen others report this problem. i would consider BCAA's one of the safer supplements for sure.
    yeah i remember seeing that somewhere, phosphatebond may have mentioned an imbalance with phenylananine (sp?)
    Tell your Girlfriend i said thanks....
    Reply With Quote

  7. #7
    nom nom nom deserusan's Avatar
    Join Date: Mar 2004
    Location: New York, United States
    Age: 44
    Posts: 28,068
    Rep Power: 57861
    deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000)
    deserusan is offline
    Only if you have Maple Syrup Urine disease. No, I 'm not screwing around and it is a real disease

    "Maple syrup urine disease (MSUD) is an aminoacidopathy secondary to an enzyme defect in the catabolic pathway of the branched-chain amino acids leucine, isoleucine, and valine. Accumulation of these 3 amino acids and their corresponding keto acids leads to encephalopathy and progressive neurodegeneration in the infant who is not treated for MSUD. Early diagnosis and dietary intervention prevent complications and may allow for normal intellectual development. "

    http://www.emedicine.com/ped/topic1368.htm
    "I just use my muscles as a conversation piece, like someone walking a cheetah down 42nd Street." - Arnold Schwarzenegger

    Heretic....
    Reply With Quote

  8. #8
    Registered User Phosphate bond's Avatar
    Join Date: Aug 2005
    Age: 50
    Posts: 6,223
    Rep Power: 6251
    Phosphate bond is a name known to all. (+5000) Phosphate bond is a name known to all. (+5000) Phosphate bond is a name known to all. (+5000) Phosphate bond is a name known to all. (+5000) Phosphate bond is a name known to all. (+5000) Phosphate bond is a name known to all. (+5000) Phosphate bond is a name known to all. (+5000) Phosphate bond is a name known to all. (+5000) Phosphate bond is a name known to all. (+5000) Phosphate bond is a name known to all. (+5000) Phosphate bond is a name known to all. (+5000)
    Phosphate bond is offline
    Originally Posted by bodybuilder45
    i thought i remember reading somewhere that creating a huge imbalance of BCAA's in comparison to other amino acids can cause depression. i think someone posted that on AM. however, i have never noticed this or seen others report this problem. i would consider BCAA's one of the safer supplements for sure.
    That's right. It wasn't me that started the thread, but I've know that BCAA competes with other "aromatic" type aminos for entry into the brain. In the case of non-exercising folks this can lead to lowered amounts of dopamine, norepinephrine, serotonin, and histamine inside the brain.

    In the case of lowered dopamine this could lead to increased Prolactin release (which would lower testosterone among other things)

    Its just something to keep in mind when taking this stuff. If you are exercising heavily enough this won't happen and you may even get a little energy boost from correcting the deficiency.

    Still I never liked the idea of BCAAs for bulking too much. Mainly because BCAA build up is more likely in this scenario.
    Reply With Quote

  9. #9
    I pWnZ tHe WeIgHtS BigRagu's Avatar
    Join Date: Sep 2004
    Location: pHiLaDeLpHiA, pA
    Age: 42
    Posts: 1,875
    Rep Power: 351
    BigRagu will become famous soon enough. (+50) BigRagu will become famous soon enough. (+50) BigRagu will become famous soon enough. (+50) BigRagu will become famous soon enough. (+50) BigRagu will become famous soon enough. (+50) BigRagu will become famous soon enough. (+50) BigRagu will become famous soon enough. (+50) BigRagu will become famous soon enough. (+50) BigRagu will become famous soon enough. (+50) BigRagu will become famous soon enough. (+50) BigRagu will become famous soon enough. (+50)
    BigRagu is offline
    i still like to use bcaa when i first wake up and during/after a workout... i usually keep a water bottle with bcaa in it next to my bed incase i wake up i can savezzzzz my muscles........
    Reply With Quote

  10. #10
    Bodyguard! excalibur's Avatar
    Join Date: May 2003
    Location: Close to a Princess!
    Age: 48
    Posts: 350
    Rep Power: 290
    excalibur is on a distinguished road. (+10) excalibur is on a distinguished road. (+10) excalibur is on a distinguished road. (+10) excalibur is on a distinguished road. (+10) excalibur is on a distinguished road. (+10) excalibur is on a distinguished road. (+10) excalibur is on a distinguished road. (+10) excalibur is on a distinguished road. (+10) excalibur is on a distinguished road. (+10) excalibur is on a distinguished road. (+10) excalibur is on a distinguished road. (+10)
    excalibur is offline
    Originally Posted by Phosphate bond
    That's right. It wasn't me that started the thread,

    Still I never liked the idea of BCAAs for bulking too much. Mainly because BCAA build up is more likely in this scenario.
    can you tell more about the bcaa build up? what does that mean?
    Reply With Quote

  11. #11
    nom nom nom deserusan's Avatar
    Join Date: Mar 2004
    Location: New York, United States
    Age: 44
    Posts: 28,068
    Rep Power: 57861
    deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000)
    deserusan is offline
    J. Nutr. 135:1531S-1538S, June 2005
    Brain Amino Acid Requirements and Toxicity: The Example of Leucine

    Glutamic acid is an important excitatory neurotransmitter of the brain. Two key goals of brain amino acid handling are to maintain a very low intrasynaptic concentration of glutamic acid and also to provide the system with precursors from which to synthesize glutamate. The intrasynaptic glutamate level must be kept low to maximize the signal-to-noise ratio upon the release of glutamate from nerve terminals and to minimize the risk of excitotoxicity consequent to excessive glutamatergic stimulation of susceptible neurons. The brain must also provide neurons with a constant supply of glutamate, which both neurons and glia robustly oxidize. The branched-chain amino acids (BCAAs), particularly leucine, play an important role in this regard. Leucine enters the brain from the blood more rapidly than any other amino acid. Astrocytes, which are in close approximation to brain capillaries, probably are the initial site of metabolism of leucine. A mitochondrial branched-chain aminotransferase is very active in these cells. Indeed, from 30 to 50% of all -amino groups of brain glutamate and glutamine are derived from leucine alone. Astrocytes release the cognate ketoacid [-ketoisocaproate (KIC)] to neurons, which have a cytosolic branched-chain aminotransferase that reaminates the KIC to leucine, in the process consuming glutamate and providing a mechanism for the "buffering" of glutamate if concentrations become excessive. In maple syrup urine disease, or a congenital deficiency of branched-chain ketoacid dehydrogenase, the brain concentration of KIC and other branched-chain ketoacids can increase 10- to 20-fold. This leads to a depletion of glutamate and a consequent reduction in the concentration of brain glutamine, aspartate, alanine, and other amino acids. The result is a compromise of energy metabolism because of a failure of the malate–aspartate shuttle and a diminished rate of protein synthesis.
    Further reading if anyone wants to know BCAA effect on the brain.
    "I just use my muscles as a conversation piece, like someone walking a cheetah down 42nd Street." - Arnold Schwarzenegger

    Heretic....
    Reply With Quote

  12. #12
    Registered User Buff_Daddy's Avatar
    Join Date: Sep 2001
    Location: australia
    Age: 39
    Posts: 3,765
    Rep Power: 5276
    Buff_Daddy is a glorious beacon of knowledge. (+2500) Buff_Daddy is a glorious beacon of knowledge. (+2500) Buff_Daddy is a glorious beacon of knowledge. (+2500) Buff_Daddy is a glorious beacon of knowledge. (+2500) Buff_Daddy is a glorious beacon of knowledge. (+2500) Buff_Daddy is a glorious beacon of knowledge. (+2500) Buff_Daddy is a glorious beacon of knowledge. (+2500) Buff_Daddy is a glorious beacon of knowledge. (+2500) Buff_Daddy is a glorious beacon of knowledge. (+2500) Buff_Daddy is a glorious beacon of knowledge. (+2500) Buff_Daddy is a glorious beacon of knowledge. (+2500)
    Buff_Daddy is offline
    Sorry to bump an old thread but this was the most recent relating to this issue.... I just have a question/issue if anyone can answer this... I know there isnt alot of strong research or evidence about this phenomenon but...

    If mega dosing bcaas can theoretically lead to imbalanaces in aa ratios responsible for mood function (ie decreased tryptophan), then could supplementing with whey (which contains tryptophan) counter this?

    Or does it need to be in free form?

    Im just concerned since I am seeking anti depressant therapy at the moment.

    Thanx
    "Knowing is not enough; we must apply. Willing is not enough; we must do."
    - Bruce Lee

    "My studying mimics my training. Brief, intense and infrequent.."
    - Big Red
    Reply With Quote

  13. #13
    nom nom nom deserusan's Avatar
    Join Date: Mar 2004
    Location: New York, United States
    Age: 44
    Posts: 28,068
    Rep Power: 57861
    deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000) deserusan has much to be proud of. One of the best! (+20000)
    deserusan is offline
    Originally Posted by Buff_Daddy
    Sorry to bump an old thread but this was the most recent relating to this issue.... I just have a question/issue if anyone can answer this... I know there isnt alot of strong research or evidence about this phenomenon but...

    If mega dosing bcaas can theoretically lead to imbalanaces in aa ratios responsible for mood function (ie decreased tryptophan), then could supplementing with whey (which contains tryptophan) counter this?

    Or does it need to be in free form?

    Im just concerned since I am seeking anti depressant therapy at the moment.

    Thanx
    Yes..........if you are getting enough whole protein sources with a full AA profile including a full EAA profile (including tryptophan which all EAA supplements lack) than you should be ok.
    "I just use my muscles as a conversation piece, like someone walking a cheetah down 42nd Street." - Arnold Schwarzenegger

    Heretic....
    Reply With Quote

  14. #14
    Registered User jmd8806's Avatar
    Join Date: Mar 2011
    Age: 36
    Posts: 1
    Rep Power: 0
    jmd8806 has a little shameless behaviour in the past. (-10) jmd8806 has a little shameless behaviour in the past. (-10) jmd8806 has a little shameless behaviour in the past. (-10) jmd8806 has a little shameless behaviour in the past. (-10)
    jmd8806 is offline
    they give me gas like no other, that plus protein equals some pretty lethal farts... Sorry bout em'
    Reply With Quote

  15. #15
    Mr. Fluff cumminslifter's Avatar
    Join Date: Sep 2011
    Location: United States
    Posts: 33,551
    Rep Power: 68619
    cumminslifter has much to be proud of. One of the best! (+20000) cumminslifter has much to be proud of. One of the best! (+20000) cumminslifter has much to be proud of. One of the best! (+20000) cumminslifter has much to be proud of. One of the best! (+20000) cumminslifter has much to be proud of. One of the best! (+20000) cumminslifter has much to be proud of. One of the best! (+20000) cumminslifter has much to be proud of. One of the best! (+20000) cumminslifter has much to be proud of. One of the best! (+20000) cumminslifter has much to be proud of. One of the best! (+20000) cumminslifter has much to be proud of. One of the best! (+20000) cumminslifter has much to be proud of. One of the best! (+20000)
    cumminslifter is offline
    Originally Posted by jmd8806 View Post
    they give me gas like no other, that plus protein equals some pretty lethal farts... Sorry bout em'
    nice bump to post content
    BA in Nutrition Science
    online coaching
    1836 meet total
    Reply With Quote

  16. #16
    lowest scum of the boards PicoSlim's Avatar
    Join Date: Apr 2011
    Location: Hungary
    Age: 77
    Posts: 42
    Rep Power: 0
    PicoSlim is not very well liked. (-100) PicoSlim is not very well liked. (-100) PicoSlim is not very well liked. (-100) PicoSlim is not very well liked. (-100) PicoSlim is not very well liked. (-100) PicoSlim is not very well liked. (-100) PicoSlim is not very well liked. (-100) PicoSlim is not very well liked. (-100) PicoSlim is not very well liked. (-100) PicoSlim is not very well liked. (-100) PicoSlim is not very well liked. (-100)
    PicoSlim is offline
    Originally Posted by cumminslifter View Post
    nice bump to post content
    ...waited 2 years to get in just the right fart joke. It was a huge win.
    Reply With Quote

  17. #17
    Registered User NikateenFiend's Avatar
    Join Date: Apr 2013
    Age: 40
    Posts: 13
    Rep Power: 0
    NikateenFiend has a little shameless behaviour in the past. (-10) NikateenFiend has a little shameless behaviour in the past. (-10) NikateenFiend has a little shameless behaviour in the past. (-10)
    NikateenFiend is offline

    Talking

    Originally Posted by PicoSlim View Post
    ...waited 2 years to get in just the right fart joke. It was a huge win.
    Lmfao that's great
    Reply With Quote

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts