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Old 02-18-2005, 11:31 AM   #1
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liver studies..

anyone have any studies like this one???


Androgens and liver tumors: Fanconi's anemia and non-Fanconi's conditions.

Velazquez I, Alter BP.

Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland 20892, USA.

The association between anabolic androgenic steroids and liver tumors was first noted in patients with Fanconi's anemia (FA). The hypotheses which led to this review were as follows: (1) androgen-treated individuals who do not have FA are also at risk of liver tumors; (2) parenteral as well as oral androgens may be responsible for liver tumors; (3) FA patients develop liver tumors after smaller and briefer androgen exposure than non-FA individuals; (4) the risk of hepatic neoplasms may depend on the specific androgen. Medline and Web of Science were searched for all cases of liver tumors associated with androgens. Information from individual cases was entered into a spreadsheet and descriptive statistical analyses were performed. Thirty-six FA cases and 97 non-FA cases with both nonhematologic disorders and acquired aplastic anemia (non-FA AA) were identified. The most common androgens were oxymetholone, methyltestosterone, and danazol. Hepatocellular carcinomas (HCC) were more often associated with oxymetholone and methyltestosterone, while adenomas were associated with danazol. Tumors were reported in six patients who received only parenteral and not oral androgens. FA patients were younger than non-FA patients when androgen use was initiated, and the FA patients developed tumors at younger ages. Non-AA patients were treated with androgens for longer periods of time, compared with FA and non-FA AA patients. All patients on anabolic androgenic steroids are at risk of liver tumors, regardless of underlying diagnosis. The magnitude of the risk cannot be determined from currently available data, because the number of patients receiving androgens is unknown.
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Old 02-18-2005, 11:35 AM   #2
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I see a few problems here. One, they're talking about orals, yes? Of course that's no good for your liver. They don't mention the dosage or the length of the administration, but my guess is that we're talking a little longer than four weeks. I've read conflicting studies myself. Some were showing patients who were taking pretty nice dosages of anavar (I think) for over a year and didn't end up with ****ed up livers.
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Old 02-18-2005, 11:38 AM   #3
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Bottom line, its the same old same old. No conclusive evidence. They didn't even detail the trails like zach said, no dosages and no cycle lengths. I'm willing to bet these guys didn't take any liver support supplements either, or anti oxidents.
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Old 02-18-2005, 11:39 AM   #4
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i know what your saying,thats why im looking for other studies that more directly deal with other than orals,but this one wasnt just orals. this study sucked ..i need more but having trouble finding any.
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Old 02-18-2005, 02:08 PM   #5
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anabolics speed up the growth of pre-existing tumors in all parts of the body. not many studies make that distinction.
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Old 02-18-2005, 02:10 PM   #6
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Quote:
Originally Posted by ratmonkey
anabolics speed up the growth of pre-existing tumors in all parts of the body. not many studies make that distinction.
Shiat....
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Old 02-18-2005, 03:43 PM   #7
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don't worry guys. in like 10 years i'll prob be dead from tumors induced by steroid use. i plan on donating my liver and kidneys for aas research.
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