What Does SizeOn V2 offer that all the other suppliments already don't??

[kincaid82]

Originally Posted by DRR32890

so would you say you prefer the new max performance over the carb free?

I like having the carb free version, and in fact plan to buy both, but if i can figure the max performance in with my cals, then it really is a great option.

[DRR32890]

Originally Posted by kincaid82

I like having the carb free version, and in fact plan to buy both, but if i can figure the max performance in with my cals, then it really is a great option.

sweet man, thanks

[triplewhammy]

Originally Posted by deserusan

Well I can tell you we don't include ffAA's or creatine in our protein totals which is a clear FDA labeling violation like some companies do.

I've always wondered about that...

[jphansen]

Originally Posted by I_Enigma_I

What Does SizeOn V2 offer that all the other suppliments already don't??
also when does it come out?? Exact date

SizeOn v2 yesterday gave me great results. I'd have to do a few more workouts on it to be sure, though. (By "great" I mean not distinguishable from my usual IntraBolic + SizeOn.)

The big differences I see are the carb matrix (I normally go with malto/dex, not sure about the efficacy of those new sugars), creatine matrix, and the additions seem to be the good forms of b vits, whey peptides, and leucine + valine + isovaline.

Overall to me it looks similar to IntraBolic + SizeOn1 minus BA, plus b vits. Not sure of the quality of the hydrolysate. But overall it kept me going and tasted good.

As great as it is, I expect it will be too pricey for me, and plan on going with IntraBolic w/creatine mono and malto/dex.

[deserusan]

Originally Posted by NO HYPE

It is well known throughout the supplement industry that R-- K------

Why did you leave out all the bad...lol? I'll start answering your questions when you tell me how creatine nitrate is better or more cost effective than creatine monohydrate ($20 retail for a 1KG) and a nitrate donor (sodium nitrate is $25 for 50KG). According to Neuron, it ionizes in solution so bonding doesn't seem to do much eh?

[GeneGnomeX]

Originally Posted by NO HYPE

Does enhanced nitric oxide production, [not] enhance skeletal muscle and growth?

Please show me convincing evidence that enhancing nitric oxide at still physiological levels will do so.

Originally Posted by NO HYPE

How so, if time-to-exhaustion is extended? I agree more research is needed however, the following abstract seems to contradict your statement.

Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans
J Appl Physiol 107: 1144-1155, 2009. First published August 6, 2009; doi:10.1152/japplphysiol.00722.2009. 8750-7587/09
Stephen J. Bailey,1 Paul Winyard,2 Anni Vanhatalo,1 Jamie R. Blackwell,1 Fred J. DiMenna,1 Daryl P. Wilkerson,1 Joanna Tarr,2 Nigel Benjamin,2 and Andrew M. Jones1

Pharmacological sodium nitrate supplementation has been reported to reduce the O2 cost of submaximal exercise in humans. In this study, we hypothesized that dietary supplementation with inorganic nitrate in the form of beetroot juice (BR) would reduce the O2 cost of submaximal exercise and enhance the tolerance to high-intensity exercise. In a double-blind, placebo (PL)-controlled, crossover study, eight men (aged 19?38 yr) consumed 500 ml/day of either BR (containing 11.2 ? 0.6 mM of nitrate) or blackcurrant cordial (as a PL, with negligible nitrate content) for 6 consecutive days and completed a series of "step" moderate-intensity and severe-intensity exercise tests on the last 3 days. On days 4?6, plasma nitrite concentration was significantly greater following dietary nitrate supplementation compared with PL (BR: 273 ? 44 vs. PL: 140 ? 50 nM; P < 0.05), and systolic blood pressure was significantly reduced (BR: 124 ? 2 vs. PL: 132 ? 5 mmHg; P < 0.01). During moderate exercise, nitrate supplementation reduced muscle fractional O2 extraction (as estimated using near-infrared spectroscopy). The gain of the increase in pulmonary O2 uptake following the onset of moderate exercise was reduced by 19% in the BR condition (BR: 8.6 ? 0.7 vs. PL: 10.8 ? 1.6 ml?min?1?W?1; P < 0.05). During severe exercise, the O2 uptake slow component was reduced (BR: 0.57 ? 0.20 vs. PL: 0.74 ? 0.24 l/min; P < 0.05), and the time-to-exhaustion was extended (BR: 675 ? 203 vs. PL: 583 ? 145 s; P < 0.05). The reduced O2 cost of exercise following increased dietary nitrate intake has important implications for our understanding of the factors that regulate mitochondrial respiration and muscle contractile energetics in humans. http://jap.physiology.org/cgi/conten...act/107/4/1144

From the full text:

We wish to stress here that while the 16% improvement in the time to task failure during severe constant-work-rate exercise is impressive, the magnitude of effect would be expected to be much smaller during time-trial exercise tasks in which a given distance is completed in the shortest possible time (34).

[deserusan]

Originally Posted by NO HYPE

Wow. Alert the presses and scientific journals. A [brand new] novel/patent pending creatine has not yet been peer-reviewed! Looks like anyone interested in the potential effects of creatine nitrate will have to use the science-based evidence on creatine monohydrate and nitrates, in order to put 2 & 2 together.

Thanks for avoiding the question.

Originally Posted by NO HYPE

How about an [all-in-one], HPLC verified product which comes in a 6 capsule dose of creatine nitrate, creatine HCL, creatine anhydrous, orotic acid, vitamin C, NAC, magnesium gluconate, ect. Did I mention the fact that creatine HCL has been demonstrated to aquire a 47% increase in plasma AUC than that of creatine monohydrate [Donald W. Miller, The 6th Annual ISSN Conference and Expo, June 2009]? Additionally, creatine HCL aquires a [significantly] greater aqueous solubility than does creatine monohydrate/pyruvate/and/or dicitrate.

I asked you about creatine nitrate and thanks again for avoiding the question. However, this brings up another questions, if creatine nitrate is superior, why does it need to be stack with other forms of creatine?

Originally Posted by NO HYPE

In terms of the initial stages of intramuscular PCr saturation.... yes, absolutely. Significantly improving the solubility and/or plasma AUC than that of creatine monohydrate results in significantly improved bioavailability [via smaller doses] in the initial stages of saturation.

Over what time period? Over 28 days it doesn't seem to. Do you have a study showing a saturation point achieved in less than 28 days?

Originally Posted by NO HYPE

Nitrate tolerance is not an issue with the addition of vitamin C and NAC, accompanied by occasional nitrate-free intervals.

Study on your product showing this?

Originally Posted by NO HYPE

It was a suggestion.... get over it. I see no reason why every NO product should [not] utilize nitrates, as their efficacy in enhancing systemic NO production is irrefutable.

Broad strokes kill folks my friend as does lack of clinical data. If the L-arginine/NO synthase pathway is dysfunctional I would agree. Too much nitrate/nitrite is not a good thing and research certainly agrees that a diet with adequate amounts of vegetables offers plenty nitrates in levels that are healthy.

Originally Posted by NO HYPE

No "rudeness" here.... just facts. Take your drama somewhere else.

lol..I think just about every member who has read this thread knows who incited the drama.

Originally Posted by NO HYPE

Speaking of avoiding previous statements, why don't you elaborate on the following?

http://forum.bodybuilding.com/showpo...1&postcount=77

As I've said numerous times, answer my question and I'll answer yours.

Originally Posted by NO HYPE

I just figured Gaspari might be a bit more interested in compounds as novel as creatine nitrate. Oh well.

Not really, no offense.

Originally Posted by NO HYPE

Does enhanced nitric oxide production, [not] enhance skeletal muscle and growth?

It can, but too much is cytotoxic. Care to share the threshold of creatine nitrate with some clinical research on it? Lastly, I'd like to thank you for avoiding the question as to how ionized creatine and ionized nitrate which is what happens to creatine nitrate (according to a former Thermo rep who is quite bright) is any "better" or cost effective [just added that] than creatine monohydrate ($20KG) and sodium nitrate ($0.50KG)?

[deserusan]

Originally Posted by GeneGnomeX

From the full text:

I remember once upon a time some guy on the forum stressed the importance of reading the full text vs. just an abstract. You're blog entry was great by the way.

[deserusan]

Originally Posted by blixmpi

Sounds reasonable to me - thanks for the response - I didn't know it had to be dosed that high and that the ingredient was so expensive.

Looking forward to giving Size-On V2 a go!

Anytime man.