aromasin vs arimidex: better AI?

[torinalth]

I've been reading some small things here and there that I can't seem to find an answer to. If someone can point me in the right direction I'd appreciate it.

The last thing I need for my cycle is my AI to have on hand just in case. I was origionally going to go with arimidex, however I have seen people mention here and there that aromasin is better. The question I have is why? one person said it was stronger, but that is not what I was interested in. the other posts seemed to be entailing about better for the body, and for "Other" reasons that I could never seem to track down.

So was I just reading crap? or is there a reason for aromasin being chosen over Arimidex? or is Arimidex the better call? For the purpose both will be equally as strong for my needs, it's more of a finding out what the unknown the aromasin seems to be holding that I can't find.

T

[javin86]

adex= stronger, but more side effect ie: hard on lipids, joints, can cause rebound etc.

aromasin= not as strong, but far less side effects.

[Drumkid20]

"strong" is dose dependent. Try 50mg a day of Aromasin - you'll start to get those good old joint problems.

My vote is for aromasin. Your not comparing apples to apples though, ones a steroidal inhibitor (aromasin) and ones just an inhibitor.

[JpRus]

Originally Posted by Drumkid20

"strong" is dose dependent. Try 50mg a day of Aromasin - you'll start to get those good old joint problems.

My vote is for aromasin. Your not comparing apples to apples though, ones a steroidal inhibitor (aromasin) and ones just an inhibitor.

so why do some ppl swear adex is better for estrogen control.

[Troy_Trinity]

it depends how strong of an ai you need...

[ThisBigBastard]

Interested as well...

Would 50mg/day of Proviron be effective at keeping estrogen under control or does it have no effect on estrogen at all?

[Drumkid20]

Originally Posted by ThisBigBastard

Interested as well...

Would 50mg/day of Proviron be effective at keeping estrogen under control or does it have no effect on estrogen at all?

Probably not a high enough dose.

People who swear adex is better are just people who swear adex is better, nothing more. I walked into a dodge dealer the other day he told me a challenger was the best car money can buy today bar none. People always have opinions.

Its a dosage game, mg for mg sure arimidex is much more powerful.

[JpRus]

Originally Posted by Drumkid20

Probably not a high enough dose.

People who swear adex is better are just people who swear adex is better, nothing more. I walked into a dodge dealer the other day he told me a challenger was the best car money can buy today bar none. People always have opinions.

Its a dosage game, mg for mg sure arimidex is much more powerful.

Yeah I assumed the same.

[Drumkid20]

Whatever works for you, if you have extensive experience with adex and aromasin just isn't the same I'm not going to sit here and type that one is somehow 'scientifically' better than the other, but I feel somehow 'stronger' on aromasin and fuller. It's better on my liver not that I'm overly concerned but lots of these things over long term use can lead to tumor growth in the liver.

[ilalin]

Some argue that Aromasin has less of an effect on lipid inversion. Thus, it might be a better choice during a cycle of moderate dosage of aromatizable steroids.

[SpanishLEGS]

To me is Aromasin hands down... With arimidex you feel like crap and with aromasin its just the opposite...
Anyway, to my friends with test at high dosages arimidex is better option to supress unwanted estrogen. To someone using moderate doses like me (350-500mg) aromasin is the way to go
I know even some people who do "bridge cycles" with aromasin+var+2 test patches daily (yes, I know var is supressive even in low dosages) but they have never complain about any problems, bad bloodwork or even dry joints...

[ralph4u2c]

proviron is always my choice in any and every cycle. if it is not enough i always have nolva and aromasin on hand to help combat the problem but it typically is. out of the two i would opt for aromasin EOD or even E3D depending on cycle and individual potentials. just remember to control estrogen and not suppress it. if i didnt have proviron always on hand i wouldnt even use an AI until/if need be.

[Kraftydog]

they are different and the way that they suppress estrogen levels, including the extent to which the suppress estrogen within tissue types as well as the profile of suppression.

for example, normal doses of aromasin do not significantly affect testicular synthesis of estrone, doses of dex do. Doses of letrozole significantly suppress testicular aromastase (and because of that estrone synthesis). Now this only really matters in people that are not suppressed, but they extend to other tissues.


exemestane is actually more potent at suppressing plasma estradiol, than dex, even at full dose. Of course the full dose of dex, suppresses estrone synthesis completely (well within tested models).

[Camel_Toad]

Originally Posted by SpanishLEGS

To me is Aromasin hands down... With arimidex you feel like crap and with aromasin its just the opposite...

Feel like crap? Are you talking mood wise or joint pain wise or what?

[PapaSmirf]

Aromasin is stronger, superior at estrogen reduction, and virtually side free.

25mg ED FTW, just be sure to get liquid anchillaries for true potency. Tabs are far less potent IME.

[car00]

I've used both and aromasin gets my vote...no rebound effect when you come off

[HumpStrap]

bump for quality thread

[GTLifter]

if i ran test e at 500mg for 12weeks with Dbol at 40mg for 6 weeks would 10mg of aromasin ED be enough on cycle to keep E levels in check?

[car00]

Originally Posted by GTLifter

if i ran test e at 500mg for 12weeks with Dbol at 40mg for 6 weeks would 10mg of aromasin ED be enough on cycle to keep E levels in check?

Aromasin comes in 12.5 or 25mg, but 12.5 ED would be enough! Some bump it a little higher while taking the Dbol, but that is really dependent on you.

[GTLifter]

Originally Posted by car00

Aromasin comes in 12.5 or 25mg, but 12.5 ED would be enough! Some bump it a little higher while taking the Dbol, but that is really dependent on you.

well i found some in liquid form thats 10mg per ml packaged as a research chem

[BrianEE93]

You have to be careful with Aromasin(Exemestane) because it is a aromatase inactivator which knocks the aromatase out completely. If you go too low on E2, it will take a while to get it back up because your body will have to produce new aromatase.

Arimidex on the other hand is a aromatase inhibitor. It binds up the aromatase receptors and slows down the conversion T-->E2. Once lowering the dose or stopping, E2 will come back up fairly quickly.

Either works well so whatever works good for you is best.

[Camel_Toad]

Originally Posted by PapaSmirf

just be sure to get liquid anchillaries for true potency. Tabs are far less potent IME.

really? I would think the odds of getting a completely bunk or improper amount of active ingredient would be higher with liquids. Mine is manufactured and packaged by a pharma manufacturer that starts with a G and also has a Z in it.. I read from at least one anonymous person that they think their aromasin tabs are spot on. :/

[Cape1]

Adex vs. aromsin is not really a good argument/comparison because you're talking about two different drugs that can have two different impacts.

"Adex highly suppresses estrone (weak estrogen) since it is almost entirely produced in the central tissues most easily saturated by these compounds. Since estradiol is generally produced by peripheral aromatization, exemestane tends to be the better option for most people, especially those with even moderate bodyfat (since such is a high level source of peripheral aromatase production)." Macro, PM

"but as mentioned, exemestane is generally the best option for long term use. its not the best option for everyone or for every situation, sometimes the high level central and peripheral suppression that full dose letrozole provides is needed (in active treatment of gynecomastia)--- though as also stated generally exemestane is effective there as well (but not always)." Macro, PM

I actually summarized this and posted the question and the response I'm getting from those who know this stuff is that if you're taking Testosterone, you really want to target peripheral Aromatization and Aromasin is better at that task. People feel like **** on Adex because even a small dose obliterates an already weak estrogen (estrone - centrally produced).

At least this is how I understand it. I'm no expert here so take it for what it's worth.

[mikialjan]

Originally Posted by Cape1

Adex vs. aromsin is not really a good argument/comparison because you're talking about two different drugs that can have two different impacts.

"Adex highly suppresses estrone (weak estrogen) since it is almost entirely produced in the central tissues most easily saturated by these compounds. Since estradiol is generally produced by peripheral aromatization, exemestane tends to be the better option for most people, especially those with even moderate bodyfat (since such is a high level source of peripheral aromatase production)." Macro, PM

"but as mentioned, exemestane is generally the best option for long term use. its not the best option for everyone or for every situation, sometimes the high level central and peripheral suppression that full dose letrozole provides is needed (in active treatment of gynecomastia)--- though as also stated generally exemestane is effective there as well (but not always)." Macro, PM

I actually summarized this and posted the question and the response I'm getting from those who know this stuff is that if you're taking Testosterone, you really want to target peripheral Aromatization and Aromasin is better at that task. People feel like **** on Adex because even a small dose obliterates an already weak estrogen (estrone - centrally produced).

At least this is how I understand it. I'm no expert here so take it for what it's worth.

good post bro

[Iron_E]

As much as I'd like to have Aromasin, all I could get my hands on was Arimidex

I'm running 16 weeks of Test/EQ @ 600/600
I'll be using HCG on and off throughout the cycle, Nolva/Clomid for PCT

My question is should I run the Aromasin throughout the cycle (EOD or E3D), or just keep it on hand in case of estrogen sides?

[nixon08]

Originally Posted by BrianEE93

You have to be careful with Aromasin(Exemestane) because it is a aromatase inactivator which knocks the aromatase out completely. If you go too low on E2, it will take a while to get it back up because your body will have to produce new aromatase.

Arimidex on the other hand is a aromatase inhibitor. It binds up the aromatase receptors and slows down the conversion T-->E2. Once lowering the dose or stopping, E2 will come back up fairly quickly.

Either works well so whatever works good for you is best.

Yeah I created a thread about this awhile ago. What scares me about Aromasin is that it irreversibly binds to the aromatase, therefore preventing each particular aromatase enzyme from ever completing their task of converting androgens into estrogens.


Now yeah at some point I'm sure the body can return itself to normal estrogen levels by creating new aromatase, but who knows how long that can actually take. Can anyone produce any studies showing how quickly the body produces new aromatase? I'm very curious.


Nixon

[Cape1]

Originally Posted by Iron_E

As much as I'd like to have Aromasin, all I could get my hands on was Arimidex

I'm running 16 weeks of Test/EQ @ 600/600
I'll be using HCG on and off throughout the cycle, Nolva/Clomid for PCT

My question is should I run the Aromasin throughout the cycle (EOD or E3D), or just keep it on hand in case of estrogen sides?

You'll get different responses on this but my way of thinking is along the lines of "an oz. of prevention......."

It's much easier to prevent Estrogen related problems than it is to reverse them once they manifest themselves in nasty side effects.

NOt sure about Adex dosing because I have never used it and wont. For Aromasin, 6.25 - 12.5 mg ED is plenty to keep E under control but not crush it. For Adex, again check it out first, but I'm given to understand that even .125mg ED is more than enough to keep things under control.

[strength777]

Originally Posted by torinalth

I've been reading some small things here and there that I can't seem to find an answer to. If someone can point me in the right direction I'd appreciate it.

The last thing I need for my cycle is my AI to have on hand just in case. I was origionally going to go with arimidex, however I have seen people mention here and there that aromasin is better. The question I have is why? one person said it was stronger, but that is not what I was interested in. the other posts seemed to be entailing about better for the body, and for "Other" reasons that I could never seem to track down.

So was I just reading crap? or is there a reason for aromasin being chosen over Arimidex? or is Arimidex the better call? For the purpose both will be equally as strong for my needs, it's more of a finding out what the unknown the aromasin seems to be holding that I can't find.

T

well

I posted lab results that you saw and still didn't believe me when I said that aromasin raised my igf over 100 points after dropping adex. So what more do you want me to say?? It has been well documented that adex can negatively affect lipids and more recently has been shown to have a negative impact on serum igf-1 levels in some people. After getting labs done for my trt therapy and showing almost out of range on the low side of igf. I switched to aromasin. almost 4 weeks later my igf-1 levels went up over 100 points. No other changes in doseages or medications took place.. Also my estradiol levels went down further, by about 6 points.

[strength777]

my lipids also improved 20 points

[Cape1]

Originally Posted by strength_77

my lipids also improved 20 points

This is great! I mean, you're lipids can take a hit anyway during most cycles so there is no sense in adding an ancillary that is known to crush them.

The more I read about this topic, the more I think Adex is useless as an AI for cycle purposes.