My thoughts- L-Dopa in itself can actually lower BP in hypertensive subjects, and in vitro (kidney tubular cells) ephedrine can actually decrease the uptake of L-Dopa and production of dopamine in...
During the Baseline period, all three patients had minor fluctuations in GH levels, within the 0.2-2.5 ng/mL range, with a 2.5 ng/mL reading being the outlier, with the next largest value at 1.4...
There were two separate days of testing: Testing Day 1 (1), where each subject received a dosage of HGH-UP™, and Testing Day 2 (2), where none of the subjects received a dosage...
To answer your question, yes, the one posted was the greatest, but the average peak GH was around 11.8 ng/mL from an average baseline of 0.496 ng/mL This is the pilot research we did back in 2009...
correct- the functionals are different, but the ring structure is similar- I do see what you are saying- the methoxy groups are more similar to reticuline (the inhibitory metabolite), and colchicine...
Nope- higenamine and colchicine share structural characteristics in common- higenamine is really unlikely to have adjunct studies on drug-drug interactions, but Colchicine does, since it is a...
Meh- no time- you raised some good points, and there is quite a bit of overlap amongst some other components- this is a separate thread anyway. You can make the argument that p-gp will have some...
Most companies use very similar channels- but the thing is, most of these guys use contract manufacturers, who are sourcing the raw materials for them; this is almost, but not 100% always, I can...
Most likely- probably hit you a lot harder- kind of scared to try this, but it will "up the ante" so to speak when it comes to creating a front-end onset (rush)
To finish my thought from earlier- you have high blood levels of naringenin (the aglycone of naringin) post-cleavage; the modulation of p-gp/MDR (the MDRI gene encompasses an entire family) is what...
Oh yeah- here is some info on P-Gly and P450-3A4- may help you guys out if you are a little confused on some of the terminology...... this is from Honda et al 2004......
OK- interesting that you come to this conclusion, but based on polyphenol metabolism, I don't think this is a stretch at all- I have read through Park's study, but based on the data about stucture...
Gotcha- this is a valid concern, and I tried to be as mindful as possible concerning half-life when it comes the components and their metabolites, and I tried to control the theoretical AUC for the...
