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  • How much Fin are using ? Aromatase Inhibitors can...

    How much Fin are using ? Aromatase Inhibitors can have a negative impact on HDL lipoproteins .
  • what concentration are you armidex pills ? 100mcg...

    what concentration are you armidex pills ? 100mcg would be hard to determine from my 1mg concentration armidex.
  • its basically a endogenous steroid bio-synthesis...

    its basically a endogenous steroid bio-synthesis pathway and the enzymes that convert one compound to another. main problem is blocking 5areducatase with FIN or DUT also disrupts other bio-synthetic...
  • i have used about 0.5 mg Arimidex 2x per month....

    i have used about 0.5 mg Arimidex 2x per month. seems to help a little bit with short term memory / cognition
  • I have been using 100mg of exogenous pregnenolone...

    I have been using 100mg of exogenous pregnenolone to sort of counteract the lowered endogenous neurosteroid levels. I only 0.5 mg of fin 2x/week and I am on 200mg of exogenous C19H28O2/week....
  • the impaired synthesis of CNS neurosteroids I...

    the impaired synthesis of CNS neurosteroids I think is the worst side effect of taking Fin.
  • fin being lipophilic crosses the cell membrane...

    fin being lipophilic crosses the cell membrane and goes to the nucleus where it inhibits transcription of DNA to mRNA. in the medical physiology text books it's always mentioned that the genes...
  • started oral Pregnenolone at 50 mg/day to...

    started oral Pregnenolone at 50 mg/day to counteract the fin induced brain fog / memory loss. will see if it works.
  • Going to start supplementing with exogenous...

    Going to start supplementing with exogenous allopregnanolone. Hope it can ameliorate some of the 5ARI side effects .
  • Is there any exogenous pharmacologic form of...

    Is there any exogenous pharmacologic form of 5α-reduced neurosteroids that Finasteride users can supplement with to counteract the "brain fog" / stress / anxiety / GABA ?
  • been on Fin since 2013 EOD 1.25 mg been off Fin...

    been on Fin since 2013 EOD 1.25 mg
    been off Fin for 11-12 days now. Buzzed hair down. will see what happens


    https://i.imgur.com/aEg1vij.jpg
    https://i.imgur.com/n7b0UdI.jpg
  • I'll be applying for a psychiatry residency...

    I'll be applying for a psychiatry residency program lol.
  • DHT binds to Androgen Receptors in the CNS. For...

    DHT binds to Androgen Receptors in the CNS. For me Finasteride impairs my short term memory, cognition, ability to articulate my thoughts, motivation / aggression , also my anxiety is worse on Fin.
    ...
  • can you explain the Sympathetic nervous system...

    can you explain the Sympathetic nervous system activity and Fin/DHT relationship.
  • I can attest to this as well. It impairs your...

    I can attest to this as well. It impairs your immediate short term memory.
  • oh man sorry to hear that, step 1 is nothing to...

    oh man sorry to hear that, step 1 is nothing to mess around with. good luck on the boards!

    Here is my blood work on finasteride and anastrozole 0.5-1mg 2x week. as you can see the estradiol is...
  • Same here. When I speak I used to have like a big...

    Same here. When I speak I used to have like a big vocabulary bank in my head now my sentences don't "flow" like they once did pre - fin .
  • yeah the AI definitely helps. Keeps my thinking...

    yeah the AI definitely helps. Keeps my thinking and mind sharp, memory, cognition, articulation of words etc. I am in medical school, and for me recall of information, and critical thinking is really...
  • The articulating words and cognition side effect...

    The articulating words and cognition side effect really bothers me as well. I take 1mg of Anastrozole twice a week now and I think now I can speak more clearly, and I have a better short term memory,...
  • I figured since fin increases estradiol I would...

    I figured since fin increases estradiol I would take an aromatase inhibitor to lower the estradiol . It seems to be working for the cognition/ thinking / memory etc.
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