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Also, the 2 gram study seems dodgy as meat eaters have higher creatine stores then vegetarians. Meat eaters on average consume 1-1.2 grams a day.

So 2 grams or lower should make a difference to...

So 3 grams without a loading phase is fine?

Following an initial loading phase, yes.[/QUOTE]

The following study states that 3 grams a day has the same effect as a loading dose

http://www.ncbi.nlm.nih.gov/pubmed/8828669

Will 2 grams a...

Thanks

Does this mean you advise a loading phase? It is known that 3 grams a day will cause maximal pcr saturation.

Is this study is a load of rubbish?

Here is the full article. Look at table 7

http://www.udel.edu/PT/PT%20Clinical%20Services/journalclub/sojc/99_00/feb00/volek.pdf

So whats left is

Increase acne, body hair
Increases aggression/antisocial behavior
Improve sex life
Reduce estrogen
Up-regulates the gene expression of hypocretin (also called orexin),...

NO HYPE, The following studies suggest 2 grams per day isn't enough

Reference 1: no increase in muscle creatine concentration using two grams of creatine per day even after six weeks: ...

What do you make of these studies NO HYPE? The two studies use low doses and don't increase muscle creatine stores?

NO HYPE, The following studies suggest 2 grams per day isn't enough

Reference 1: no increase in muscle creatine concentration using two grams of creatine per day even after six weeks: ...

The testicular atrophy doesn't happen, as creatine doesn't reduce testosterone.

Also, it increases DHT:T ratio which makes you a homo - http://www.ncbi.nlm.nih.gov/pubmed/15677419

DHT doesn't...

It wasn't stabilised, it went down from 56% to 40%. I accept that a 40% increase is not the 6-700% increase that a DHT injection causes.

I still think it is reasonable to assume that some of...

Should I be worried by this increase in DHT? I've looked through pubmed for effects of DHT.

Increases aggression/antisocial behavior
Improve sex life
Causes reversible testicular atrophy...

3 grams, 3 times a week is 1.28 grams a day. If creatine synthesis was to go down by 30% (0.6g), this would mean we only need 0.68 grams per day. This seems really low. Is the 0.6 grams figure a poor...

NO HYPE, you say 3-5 gram, 3x a week. Could I go with the 3 gram estimate? Or is 5 grams a safer bet?

30% less precursors surely reduces endogenous synthesis by a significant amount. If endogenous...

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NO HYPE, the following study from an earlier page, indicates that creatine affects endogenous synthesis.

whttp://jap.physiology.org/content/97/3/852.full

Doesn't this mean you need to take in...

So should it be cycled?

Never mind

I can now fully rebuff this. Atp doesn't deplete at daytime. It stays the same from morning to bedtime. So, I needn't worry about creatine supplementation postponing depletion.