Fenugreek = Growth hormone
This is my first post, but been bodybuilding for years. I am interested in the supplement side like most folks but have yet to find anything really hot.
I have found this article on fenugreek in an experiment with rats that states that fenugreek releases lots of growth hormone.
What do you think?
Rat growth-hormone release stimulators from fenugreek seeds.
Shim SH, Lee EJ, Kim JS, Kang SS, Ha H, Lee HY, Kim C, Lee JH, Son KH.
Source
School of Biotechnology, Yeungnam University, Gyeongsan 712-749, Korea.
Abstract
Bioassay-guided fractionation of MeOH extract from fenugreek (Trigonella foenum-graecum L.) seeds resulted in the isolation of two rat growth-hormone release stimulators in vitro, fenugreek saponin I (1) and dioscin (9), along with two new, i.e., 2 and 3, and five known analogues, i.e., 4-8. The structures of the new steroidal saponins, fenugreek saponins I, II, and III (1-3, resp.), were determined as gitogenin 3-O-beta-D-xylopyranosyl-(1-->6)-beta-D-glucopyranoside, sarsasapogenin 3-O-beta-D-xylopyranosyl-(1-->6)-beta-D-glucopyranoside, and gitogenin 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside, respectively. Fenugreek saponin I (1) and dioscin (9) caused ca. 12.5- and 17.7-fold stimulation of release, respectively, of rat growth hormone from rat pituitary cells, whereas gitogenin (5) showed moderate activity. To our knowledge, this is the first study to demonstrate that steroidal saponins stimulate rat growth-hormone release in rat pituitary cells.
PMID:
18816528
[PubMed - indexed for MEDLINE]
I am thinking about using an extract for a while to see what happens, I've tried the powder before and it does make you quite smelly.
I would like to know dosages and standardised values.