**The Anabolic/Androgenic Dosages & Effects of Formestane**
[center][b]**The Anabolic/Androgenic Dosages & Effects of Formestane**[/center][/b]
After receiving numerous PM's about Formestane and proper dosing protocol, I was compelled to create this thread, in which I will outline the proper and effective use of Formestane products.
[b]Formestane(4-Hyroxyandrostenedione) is a steroial aromatase inhibitor and a prohormone to the anabolic steroid 4-Hydroxytestosterone. It is not only effective for estrogen reduction, it is also a mild anabolic steroid.[/b] It was first patented by G.D. Searle & Co. in 1955, but it never hit the commercial market. Structurally, 4-Hydroxytestosterone is simply testosterone with a hydroxy group at the four position, making it most similar to the steroid clostebol, which has a chloro group at the four position. Formestane and Clostebol(and Halodrol/Promagnon) are very similar in effect.
4-Hydroxytestosterone is .65 times as anabolic and .25 times as androgenic as testosterone propionate. The reason that Formestane has such low androgenic activity is that the modification at the 4th position prevents DHT conversion. In vitro, 4-Hydroxytestosterone is actually a weak inhibitor of 5-alpha reductase.
[b][u]Oral Formestane[/b][/u]
Estrogen Reduction: 200-500mg
Anabolic/Androgenic effects: 500-1,000mg(*or higher)
[b][u]Transdermal Formestane[/u][/b]
Estrogen Reduction: 100-200mg
Anabolic/Androgenic effects: 300-500mg(*or higher)
[b]Formestane can be used for the following:[/b]
[i]-As a stand-alone PROHORMONE in higher dosages.
-While on cycle to reduce estrogen levels while increasing gains.
-As a Testosterone Booster.[/i]
[color=red]*[/color]I would not suggest using Formestane during PCT, at this point there is not enough data available to conclude whether or not it will inhibit HPTA recovery.
-Ross Erstling
Owner & CEO of Supreme Sports Enhancements[size=3]([url]http://www.bodybuilding.com/store/supremesports/supremesports.htm[/url])[/size]