[QUOTE=GableGrip;1029644293]Any need for choline bitartrate in an ALCAR+Noopept stack?[/QUOTE]
Try without it first. If it's working for you then no need to add it.
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[QUOTE=GableGrip;1029644293]Any need for choline bitartrate in an ALCAR+Noopept stack?[/QUOTE]
Try without it first. If it's working for you then no need to add it.
[QUOTE=PotatosGonPotat;1029642173]No reason to lower the dose. Also I don't think it was the 5 hours of sleep. Most likely the reason for your foggy and blurred vision was due the fact of taking choline and piracetam together. You ingest choline prior to piracetam for absorption purposes and timing to build up in your body. Consuming Piracetam makes your body use more choline therefore you start noticing foggy and blurred vision. Pretty much the opposite of it's intention. (Taking them together at once defeats the purpose) I don't know your schedule but you could take it first thing waking up, then take Piracetam right before going to work or school or whatever you have to do. So an hour to two spacing time.
Another thing you should know. Not everyone works the same. You have to find what works best for you. Some people do not need choline because they already have enough in their body from diet and the foods that they eat. If you're lacking choline in your diet then you start seeing the effects you noticed.
Follow my previous post and report back[/QUOTE]
Blurry vision is typically associated with excessive mAChR stimulation, which would occur in the opposite scenario that you're describing. Fogginess is almost certainly due to the lack of sleep. Piracetam may modulate the cholinergic system, but 2 grams is not going to deplete it, especially in conjunction with two ingredients that upregulate the activities of choline acetyltransferase.
You are grossly overstating the importance of timing with respect to piracetam and choline. It is also unlikely that he lacks choline via diet unless he is from a third-world country or malnourished, especially since only marginal amounts of dietary choline are actually needed for the synthesis of acetylcholine.
[QUOTE=PotatosGonPotat;1029649053]Try without it first. If it's working for you then no need to add it.[/QUOTE]
This. Its pretty much all trial and error until you get the dosing down. It all depends on the individual
[QUOTE=FullerPotato;1029654963]Blurry vision is typically associated with excessive mAChR stimulation, which would occur in the opposite scenario that you're describing. Fogginess is almost certainly due to the lack of sleep. Piracetam may modulate the cholinergic system, but 2 grams is not going to deplete it, especially in conjunction with two ingredients that upregulate the activities of choline acetyltransferase.
You are grossly overstating the importance of timing with respect to piracetam and choline. It is also unlikely that he lacks choline via diet unless he is from a third-world country or malnourished, especially since only marginal amounts of dietary choline are actually needed for the synthesis of acetylcholine.[/QUOTE]
Nice username.
I've had the same experience as he had and found the timing scheme to work best for me. Almost always had the blurry vision and fogginess taking piracetam with choline at the same time.
[QUOTE=FullerPotato;1029654963]Piracetam may modulate the cholinergic system, but 2 grams is not going to deplete it, especially in conjunction with two ingredients that upregulate the activities of choline acetyltransferase.[/QUOTE]
Moreover, when considering the fact that he only just started, the 2-grams [even as a standalone] wouldn't do chit in terms of inducing any pyrrolidone-mediated decrements in ACh.
[QUOTE=FullerPotato;1029654963]You are grossly overstating the importance of timing with respect to piracetam and choline.[/QUOTE]
Precisely Mr. Potato. Nothing wrong with coadministering the two whatsoever.
[img]http://ernstchan.com/b/src/1360944035750248.jpg[/img]
[QUOTE=PotatosGonPotat;1029662823]Almost always had the blurry vision and fogginess taking piracetam with choline at the same time.[/QUOTE]
How much choline were you taking? I ask because choline in and of itself has been anecdotally-reported to elicit brain fog with many individuals.
[QUOTE=NO HYPE;1029673783]How much choline were you taking? I ask because choline in and of itself has been anecdotally-reported to elicit brain fog with many individuals.[/QUOTE]
500 mg but you're actually right about choline's action. Although I believe the same result could be with piracetam as well.
[QUOTE=PotatosGonPotat;1029677603]500 mg but you're actually right about choline's action.[/QUOTE]
If you think I was right about this one.... do yourself a favor and get your hands on some phenylpiracetam [at least once, as it's cost prohibitive]. But yes.... it's that friggin' good. The phenyl group really opens up it's pharmacodynamic potential. It's basically piracetam on steroids.
[QUOTE=PotatosGonPotat;1029677603]Although I believe the same result could be with piracetam as well.[/QUOTE]
Well you've done assloads of piracetam, and I don't recall you mentioning that being an effect, but maybe you did.
I don't feel like thumbing through this entire thread looking for ambiguity and unanswered questions, but if anything needs clarifying you have my full attention for the next like 4 minutes. Then you have... like... some of it.
[QUOTE=PinchTheBear;1029715173]I don't feel like thumbing through this entire thread looking for ambiguity and unanswered questions, but if anything needs clarifying you have my full attention for the next like 4 minutes. Then you have... like... some of it.[/QUOTE]
Pramiracetam vs Noopept for Mood enhancement?
[QUOTE=Madevilz;1029718473]Pramiracetam vs Noopept for Mood enhancement?[/QUOTE]
Don't expect that effect from either
[QUOTE=Madevilz;1029718473]Pramiracetam vs Noopept for Mood enhancement?[/QUOTE]
From both experience and pharmacological intuition, definitely noopept, although neither is really ideal. Neurotrophic factors are a hot topic in neuropharmacology these days and potential neurotrophics are going to get a lot of attention in coming years.
[QUOTE=PinchTheBear;1029725653]From both experience and pharmacological intuition, definitely noopept, although neither is really ideal. Neurotrophic factors are a hot topic in neuropharmacology these days and potential neurotrophics are going to get a lot of attention in coming years.[/QUOTE]
Thanks. Id also like to know your thoughts on allopregnanolone. A certain company is bringing it out to the supplement market, and is hyping it up to be one of the strongest nootropic.
[QUOTE=Madevilz;1029728563]Thanks. Id also like to know your thoughts on allopregnanolone. A certain company is bringing it out to the supplement market, and is hyping it up to be one of the strongest nootropic.[/QUOTE]
Definitely definitely NOT a nootropic. Would not recommend, certainly would not use.
[QUOTE=PinchTheBear;1029730413]Definitely definitely NOT a nootropic. Would not recommend, certainly would not use.[/QUOTE]
Really? Why? Is it dangerous?
That company is also thinking about releasing it as a nasal spray.
[QUOTE=Madevilz;1029731063]Really? Why? Is it dangerous?
That company is also thinking about releasing it as a nasal spray.[/QUOTE]
I wouldn't call it dangerous, no, but I (under Synapsin's supervision) have completed a substantial body of work on GABAa and GABAb agonism and the former isn't something healthy adults should be targeting under any circumstances, in my opinion.
[QUOTE=PinchTheBear;1029715173]I don't feel like thumbing through this entire thread looking for ambiguity and unanswered questions, but if anything needs clarifying you have my full attention for the next like 4 minutes. Then you have... like... some of it.[/QUOTE]
What nootropics can you take year round without cycling?
Thanks
[QUOTE=PinchTheBear;1029732013]I wouldn't call it dangerous, no, but I (under Synapsin's supervision) have completed a substantial body of work on GABAa and GABAb agonism and the former isn't something healthy adults should be targeting under any circumstances, in my opinion.[/QUOTE]
Pinch give us your thoughts and experience using noopept. What benefits did you find from using it and at what mg?
[QUOTE=ISurfNudeBrah;1029735003]Pinch give us your thoughts and experience using noopept. What benefits did you find from using it and at what mg?[/QUOTE]
Well first of all I've used pramiracetam in high doses for as many as 30 consecutive days and felt absolutely nothing. Very disappointing. Noopept I've used at 20mg for a few weeks (in progress) and it's definitely something special, but it won't get a fair shake until I give it at least another week. I'll have more to say at the Arnold if you'd like to speak more about it in person.
[QUOTE=PinchTheBear;1029738703]Well first of all I've used pramiracetam in high doses for as many as 30 consecutive days and felt absolutely nothing. Very disappointing. Noopept I've used at 20mg for a few weeks (in progress) and it's definitely something special, but it won't get a fair shake until I give it at least another week. I'll have more to say at the Arnold if you'd like to speak more about it in person.[/QUOTE]
I would like to do that, unfortunately, I won't be at the Arnold. Maybe the Mr. O though.
For kicks, during the synthesis of t-butyl chloride (from t-butyl alcohol with concentrated HCl), what would be the purpose of washing my distallate with 10 % NaHCO3 solution after performing the initial simple distillation, and had put the distallate into a separatory funnel?
Would anyone be willing to send a sample of the stim-free Focus XT? I have Piracetam or hard cash that I could trade haha.. just don't want to buy a full tub, my mind tends to react different than everyone else's with these things.
[QUOTE=PinchTheBear;1029715173]I don't feel like thumbing through this entire thread looking for ambiguity and unanswered questions, but if anything needs clarifying you have my full attention for the next like 4 minutes. Then you have... like... some of it.[/QUOTE]
From your experience, how many lickes does it take to get to the center of a Tootsie Pop?
[QUOTE=ISurfNudeBrah;1029743103]For kicks, during the synthesis of t-butyl chloride (from t-butyl alcohol with concentrated HCl), what would be the purpose of washing my distallate with 10 % NaHCO3 solution after performing the initial simple distillation, and had put the distallate into a separatory funnel?[/QUOTE]
why are you distilling anything lol that's a 1-2 shake'n'bake wash with base to neutralize and extract unreacted agents suspended in the organic layer
LOL @ FullerPotato
[QUOTE=PinchTheBear;1029747523]why are you distilling anything lol that's a 1-2 shake'n'bake wash with base to neutralize and extract unreacted agents suspended in the organic layer[/QUOTE]
Cuz my lab instructions told me too :D, I'm doing a lab report from several weeks ago.. been procrastinating.
[QUOTE=NO HYPE;1029680613]If you think I was right about this one.... do yourself a favor and get your hands on some phenylpiracetam [at least once, as it's cost prohibitive]. But yes.... it's that friggin' good. The phenyl group really opens up it's pharmacodynamic potential. It's basically piracetam on steroids.
[/QUOTE]
Have considered it and will probably get it sometimes soon. Don't really like messing with dopamine receptors too much.
[QUOTE=Madevilz;1029718473]Pramiracetam vs Noopept for Mood enhancement?[/QUOTE]
Never tried Noopept, but Pramiracetam never really gave me much of a Mood enhancement, at least nothing noticeable. I would recommend Aniracetam, personally it always seemed to help brighten my mood in a slight way.
I've recently added Neuro Breeze - L-Theanine to my nootropic stack, and pre-workout stack. I did so because of the various claims it has concerning GABA, and am wondering if anyone else has tried this or if they know whether L-Theanine is a worthwhile addition to my pre-workout stack? Thanks in advance!
Consensus on PEA? I just picked some up, any good? tips for dosing?
[QUOTE=Goryeo;1030455233]Consensus on PEA? I just picked some up, any good? tips for dosing?[/QUOTE]
PEA is not a nootropic