Myostatin blockers

[bodybob]

Maybe soon...

http://cnn.netscape.cnn.com/ns/news/story.jsp?flok=FF-APO-1500&idq=/ff/story/0001%2F20040623%2F2027180029.htm&sc=1500&photoid=20040623NY192

[Stagger]

http://www.nytimes.com/2004/06/24/science/24muscle.html



Dr. Schuelke cited one concern: Muscle cells are surrounded by immature satellite cells that lie dormant until the muscle is injured. Then they migrate into the muscle, replacing injured or dead cells. A recent paper indicated that myostatin might normally function to keep satellite cells quiescent. Without myostatin, he said, the satellite cells might be so active building muscle that they become depleted early in life.

[nicesocks]

yeah i've read a couple articles on this today from different sources.

Really interesting stuff but I'd like to see the long term effects it has on this toddler. I hope hes okay.

[footballjunior]

what exactly is myostatin?

[nicesocks]

A protein that inhibits muscle tissue growth

[footballjunior]

thanx

[Zachattack43]

So guys we should be looking for something John Hopkins University and not Bio-test to have suitable myostatin product. Although the product will be sold to a bio/pharm company

[Big Cat]

There are two viable myostatin blockers currently available. One human recombinant propeptide and one replicant of Piedmontese myostatin. The pricetag of each is roughly 1200 dollars per mg.

[KARLMAN]

Originally posted by Big Cat
There are two viable myostatin blockers currently available. One human recombinant propeptide and one replicant of Piedmontese myostatin. The pricetag of each is roughly 1200 dollars per mg.

whats your source on this and where can i get some?

[Big Cat]

Most sources for recombinant products and research materials have it. The propeptide that is.

[gregxy]

Scientific american has an article on gene doping in the latest
issue. They talk some about myostantin. There is a picture
of a really muscular cow with a similar defect in the myostantin
gene.


Reasearchers are using a virus to introduce a new gene into
cells to increase protien production in people who have
muscular distrophy and similar illnesses.

Apparently gene doping to increase athletic preformance
may not far off. Although I can't see supliment companies
comming out with anything until years after the drug giants
do.

[codiejenkins]

Originally posted by Big Cat
Most sources for recombinant products and research materials have it. The propeptide that is.

How about a specific source?

[cardsfall]

Guys why spend ALL that money when you can just buy Pinnacle Juiced Protein with MYOZAP?

Zap myostatin with PINNACLE JUICED PROTEIN TODAY!

Stupid myostatin blocking 86 lbs of lean, mean, muscle?

PINNACLE JUICED PROTEIN with MYOZAP will turn you in a lean, mean MYOSTATIN BLOCKIN INSANE FREAK BITCH *******.





at least...that's what the ad would look like.

http://www.bodybuilding.com/store/pin/juiced.html

[sikboy]

Originally posted by cardsfall
Guys why spend ALL that money when you can just buy Pinnacle Juiced Protein with MYOZAP?
Some people do.


[i]Zap myostatin with PINNACLE JUICED PROTEIN TODAY!


Stupid myostatin blocking 86 lbs of lean, mean, muscle?

PINNACLE JUICED PROTEIN with MYOZAP will turn you in a lean, mean MYOSTATIN BLOCKIN INSANE FREAK BITCH *******.





at least...that's what the ad would look like.

http://www.bodybuilding.com/store/pin/juiced.html [/B]

^^ LOL!!!

[CaptainCode]

Originally posted by cardsfall
Guys why spend ALL that money when you can just buy Pinnacle Juiced Protein with MYOZAP?

Zap myostatin with PINNACLE JUICED PROTEIN TODAY!

Stupid myostatin blocking 86 lbs of lean, mean, muscle?

PINNACLE JUICED PROTEIN with MYOZAP will turn you in a lean, mean MYOSTATIN BLOCKIN INSANE FREAK BITCH *******.





at least...that's what the ad would look like.

http://www.bodybuilding.com/store/pin/juiced.html

Most people have found that those supplements that state they block myostatin are a complete waste of money and do nothing.

The true myostatin blocking protein seems viable at least with what research has been done. There are some people that have one gene missing or inactive and aren't producing as much myostatin as a normal person and they are fine.

They have those big cows in Europe that are surviving fine as well. I don't know how long they keep them alive though so I guess you can't base the research on cows that are killed for meat :D

[ccmhcky88]

Originally posted by Big Cat
Most sources for recombinant products and research materials have it. The propeptide that is.

So is that juiced protien with the "myozap" in is completley useless???

[Zachattack43]

Originally posted by ccmhcky88
So is that juiced protien with the "myozap" in is completley useless??? **** yea!! every product with Myostatin in does not work. do you seriously think some supplement company would beat a pharm company to come out with such a product??? Myostatin blockers are still being researched.

[Hermanito]

Originally posted by nicesocks
Dr. Schuelke cited one concern: Muscle cells are surrounded by immature satellite cells that lie dormant until the muscle is injured. Then they migrate into the muscle, replacing injured or dead cells. A recent paper indicated that myostatin might normally function to keep satellite cells quiescent. Without myostatin, he said, the satellite cells might be so active building muscle that they become depleted early in life.


So what does that mean exactly?
Does it mean that the body cannot make more satellite cells that become depleted? I can see someone taking a myostatin inhibitor and then depleting his satellite cells and then going off so the body can make new ones.

This needs a lot more research.

[Hermanito]

I found an article about myostatin and big ass cows.

http://www.piedmontese-napa.com/websitegraphics/myos%20brochure.pdf

[Big Cat]

Originally posted by Hermanito
So what does that mean exactly?
Does it mean that the body cannot make more satellite cells that become depleted? I can see someone taking a myostatin inhibitor and then depleting his satellite cells and then going off so the body can make new ones.

This needs a lot more research.

The process of creating more sattelite cells is one of clonal expansion, which means there has to be at least one undifferentiated sattelite cell to divide in order to create a new one. If they are depleted there is nothing to replicate, hence the term "depleted".

[Vinnie Bobarino]

Originally posted by zachattack43
**** yea!! every product with Myostatin in does not work. do you seriously think some supplement company would beat a pharm company to come out with such a product??? Myostatin blockers are still being researched.

Who knows anything is possible. It is possible that a supplement company can come out with a good myostatin blocker. I know it does not seem very probable, but it is possible.

There are things like M1T, Creatine, ECA, etc...

So why not Myostatin?

[sikboy]

Originally posted by Vinnie Bobarino
Who knows anything is possible. It is possible that a supplement company can come out with a good myostatin blocker. I know it does not seem very probable, but it is possible.

There are things like M1T, Creatine, ECA, etc...

So why not Myostatin?

Maybe, one day, when myostatin blockers are developed into drugs ,we may see a supplement company come out with a genuine myostatin blocker, but dont hold your breath waiting.

[RBEliminator]

Originally posted by Vinnie Bobarino
Who knows anything is possible. It is possible that a supplement company can come out with a good myostatin blocker. I know it does not seem very probable, but it is possible.

There are things like M1T, Creatine, ECA, etc...

So why not Myostatin?




Supplement companies don't have 100+ million dollars too spend in a research attempt of finding an acute myostatin blocker. Hence why it will not happen until one is discovered they can go after.

[Olliviadoc]

FYI: I have been diagnosed to have a myostatin excess. No matter how hard I exercise I cannot build muscles, I only injure myself. I have tried a couple of the supplements. (According to my massage therapist) my muscles have changed from hard and stringy to round & spongy.

[Zachattack43]

FYI: I have been diagnosed to have a myostatin excess. No matter how hard I exercise I cannot build muscles, I only injure myself. I have tried a couple of the supplements. (According to my massage therapist) my muscles have changed from hard and stringy to round & spongy.

myostatin supps dont work, simple as that

[GeneGnomeX]

myostatin supps dont work, simple as that

actually there is an OTC coming out soon by a pharma company that may actually work

[aoba]

a pharma company with an OTC? are you sure your not talking about the fertilized egg thing? I don't think thats legit to the extent people are talking about here if thats what you're thinking.

[Juic3]

interesting topic

[entrepreneur8]

http :// www .ergo-log. com/creatinemyostatin .html

had to separate link to post

[nicesocks]

http :// www .ergo-log. com/creatinemyostatin .html

had to separate link to post

That's an awesome site

[Dr.Dave1]

http :// www .ergo-log. com/creatinemyostatin .html

had to separate link to post

Interesting article but far from convincing. If you look at the original article I think you will appreciate that the website skews what the authors concluded as well. Myostatin levels dropped in strength training group compared to the no exercise group(duh); the strength training + creatinine group had a larger drop in myostatin than the strength training alone group (this would be expected with the larger increase in strength but could be a secondary effect). There was not a no exercise + creatinine group to see if creatinine alone decreased myostatin. The ergo folks put emphasis on GASP-1 levels increasing with resistance + creatinine which they did go up but not significantly more than resistance exercise alone . . . so this increase could be related to resistance training alone augmented by creatinine supplementation.

[nicesocks]

Interesting article but far from convincing. If you look at the original article I think you will appreciate that the website skews what the authors concluded as well. Myostatin levels dropped in strength training group compared to the no exercise group(duh); the strength training + creatinine group had a larger drop in myostatin than the strength training alone group (this would be expected with the larger increase in strength but could be a secondary effect). There was not a no exercise + creatinine group to see if creatinine alone decreased myostatin. The ergo folks put emphasis on GASP-1 levels increasing with resistance + creatinine which they did go up but not significantly more than resistance exercise alone . . . so this increase could be related to resistance training alone augmented by creatinine supplementation.

Good point.

I can't tell if that ergo website is legitimately unbiased or not...

[gspsilva]

I got chosen to do a log for Myo t-12.............that was in the summer, still waitin for it to be sent

[PaleoAyo]

any update lol

genetic doping is the future!!!!!