Glycolysis & Oxygen,

[Croaker]

Hey does anyone have any studies that show the actual influence of oxygen on glycolysis? I could have sworn I read some a couple months ago that found that the presence of oxygen didn't actually influence whether or not the pyruvate was used by the Krebs cycle or converted to lactic acid but I can't find them now.

If anyone knows of any studies relating to this, it would be greatly appreciated.

[yeungconrad]

From what I learned from my bcem course this semester...If I remember correctly...Glucose goes initially goes through glycolysis in order to make a high energy 3 carbon compound pyruvate which then can either go into the krebs cycle to make NADH, FADH2, & GTP. Krebs cycle only happens in the PRESENCE of oxygen because oxygen acts as a final electron acceptor to produce water and form ATP through a proton motive force.

In the absence of oxygen lactic acid is produced using lactate dehydrogenase I believe...(if I remember)..... to convert pyruvate into lactic acid. It all has to do with whether oxygen is present to be a final electron acceptor. If it isn't present then it will use something else. Hope that helps. I might be wrong.

[bloodsimple1234]

krebs cycle is fun stuff! you did pretty good conrad!